Zobrazeno 1 - 10
of 21
pro vyhledávání: '"L Iu, Alfeeva"'
Autor:
Iu A Zolotarev, E M Dorokhova, L. A. Andreeva, Igor A. Grivennikov, O. V. Dolotov, Miasoedov Nf, L Iu Alfeeva
Publikováno v:
Russian Journal of Bioorganic Chemistry. 30:213-217
The binding characteristics of the peptide Semax (Met-Glu-His-Phe-Pro-Gly-Pro) to plasma membranes of basal nuclei of the rat forebrain and the dynamics of its degradation during its incubation with these membranes were studied. Binding of the homoge
Autor:
L. A. Andreeva, Miasoedov Nf, Kamenskiĭ Aa, A.P. Bonartsev, L. S. Guzevatykh, Emel'ianova Tg, L Iu Alfeeva, A. B. Usenko
Publikováno v:
Biology Bulletin of the Russian Academy of Sciences. 29:284-289
We studied the influence of dermorphin (dermorphin) analogs with stereochemical modification of the amino acid residue proline in position 6 (Pro6), Tyr-D-Ala-Phe-Gly-Tyr-Hyp-Ser-NH2, Tyr-D-Ala-Phe-Gly-Tyr-[D-Pro]-Ser-NH2, Tyr-D-Ala-Phe-Gly-Tyr-[dehy
Publikováno v:
Bioorganicheskaia khimiia. 37(4)
Proteolysis of semax (Met-Glu-His-Phe-Pro-Gly-Pro, Sem) and its analogues ([Ala1]Sem, [Gly1]Sem, [Thr1]Sem, [Trp1]Sem) that are differ from semax in substitution of N-terminal Met residue were studied. It is shown that such replacement changes the ra
Publikováno v:
Izvestiia Akademii nauk. Seriia biologicheskaia. (6)
The effect of structural modifications in the molecule of dermorphin on the functional state of thermoregulation of rats under cold, neutral, and hot environment has been studied. Thermoregulatory and vasomotor activities of 43 peptides (fragments an
Autor:
I P, Ashmarin, K E, Baglikova, S E, Edeeva, Iu A, Zolotarev, V S, Kozik, A K, Dadaian, E M, Dorokhova, L Iu, Alfeeva, L A, Andreeva, G N, Kopylova, T S, Pavlov, B V, Vas'kovskiĭ, V K, Meshavkin, O Iu, Sokolov, N V, Kost, A A, Zozulia, G E, Samonina, N F, Miasoedov
Publikováno v:
Bioorganicheskaia khimiia. 34(4)
The distribution of the glyprolines Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selanc) was analyzed and compared in tissues of rat organs after different ways of their administration using the peptides uniformly labeled with tritium. Comparative da
Autor:
L S, Guzevatykh, T A, Voronina, T G, Emel'ianova, L A, Andreeva, L Iu, Alfeeva, S B, Seredenin, N F, Miasoedov
Publikováno v:
Izvestiia Akademii nauk. Seriia biologicheskaia. (1)
The effect of dipeptide Tyr-Pro, present in representatives of most families of opioid peptides, and two its analogs, Tyr-Pro-NH2 and Tyr-Pro-OMe, on analgesic activity was studied in different tests (tail-flick test, tail pinch (Haffner's) test, for
Autor:
D A, Vilenskiĭ, N G, Levitskaia, L A, Andreeva, L Iu, Alfeeva, A A, Kamenskiĭ, N F, Miasoedov
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 93(6)
Effects of chronic intranasal administration of ACTH(4-10) analog Semax (MEHFPGP) on exploratory activity, anxiety level, and depression-like behaviour were studied in white rats. The peptide was injected daily in dose 0.05 mg/kg during 10 or 14 days
Autor:
D M, Ivanova, D A, Vilenskiĭ, N G, Levitskaia, L A, Andreeva, L Iu, Alfeeva, A A, Kamenskiĭ, N F, Miasoedov
Publikováno v:
Izvestiia Akademii nauk. Seriia biologicheskaia. (2)
Melanocortins, peptides of the family of adrenocorticotropic (ACTH) and melanocyte-stimulating (MSH) hormones, have a wide range of physiological activity. Heptapeptide semax (MEHFPGP) is an analog of the ACTH4-10 fragment. Previously, pronounced noo
Autor:
N Iu, Glazova, E A, Sebentsova, N G, Levitskaia, L A, Andreeva, L Iu, Alfeeva, A A, Kamenskiĭ, N F, Miasoedov
Publikováno v:
Izvestiia Akademii nauk. Seriia biologicheskaia. (4)
A comparative study of neotropic activity of semax (MEHFPGP), an analogue of the ACTH(4-10), and some of its derivatives in which the N-terminal methionine was modified or substituted with other amino acid residues was performed. The effect of these
Autor:
L S, Guzevatykh, D V, Valuĭskikh, T A, Voronina, T G, Emel'ianova, L A, Andreeva, L Iu, Alfeeva, N F, Miasoedov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 68(3)
On the model of acute physical dependence, naloxone treatment of animals dependent on D-Pro6 peptide ([D-Pro6]DM) (a demorphin analog) led to tremor, shaking, convulsions, and rare jumps typical of morphine-dependent animals. The variety and intensit