Zobrazeno 1 - 10
of 24
pro vyhledávání: '"L I Rebhun"'
Publikováno v:
The Journal of Cell Biology
Tubulin was extracted from spindles isolated from embryos of the sea urchin Strongylocentrotus purpuratus and purified through cycles of temperature-dependent assembly and disassembly. At 37 degrees C, the majority of the cycle-purified spindle tubul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1624e56f4d1da52b09a9c04aed59d62f
http://europepmc.org/articles/PMC2112174
http://europepmc.org/articles/PMC2112174
Autor:
K A Suprenant, L I Rebhun
Publikováno v:
Journal of Biological Chemistry. 258:4518-4525
Tubulin was purified from unfertilized eggs of the sea urchin Strongylocentrotus purpuratus by DEAE-column chromatography and cycles of temperature-dependent assembly and disassembly. Tubulin-containing column fractions self-assemble into intact micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c50907c2155784a6e8654769239e002
https://doi.org/10.1016/s0021-9258(18)32654-1
https://doi.org/10.1016/s0021-9258(18)32654-1
Autor:
L I Rebhun, T C Keller
Publikováno v:
The Journal of Cell Biology
Tubulin was extracted from spindles isolated from embryos of the sea urchin Strongylocentrotus purpuratus, repolymerized in vitro, and purified through three cycles of temperature-dependent assembly and disassembly. In addition to the tubulin, these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3ae86c9e8195a03a70c35bb661e4ac
http://europepmc.org/articles/PMC2112172
http://europepmc.org/articles/PMC2112172
Autor:
S. M. Kupchan, L I Rebhun, Albert T. Sneden, G. A. Howie, R W Wang, Alan R. Branfman, W E McIvor, T C Schnaitman
Publikováno v:
Journal of Medicinal Chemistry. 21:31-37
In an effort to determine the structural requirements for the significant antileukemic, cytotoxic, antitubulin, and antimitotic activity exhibited by the novel ansa macrolide, maytansine (1), four new C-3 ester and six new C-9 ether homologues were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48738c8ba61b49ebbff8f3c43d55dec2
https://doi.org/10.1021/jm00199a006
https://doi.org/10.1021/jm00199a006
Publikováno v:
Science. 189:1002-1005
Maytansine, at 6x10(-8)M, irreversibly inhibits cell division in eggs of sea urchins and clams. It causes the disappearance of a mitotic apparatus or prevents one from forming if added at early stages. Maytansine does not affect formation of the mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3e4c127d3d6262f7b03cb3654a6803
https://doi.org/10.1126/science.1241159
https://doi.org/10.1126/science.1241159
Autor:
D A Begg, L I Rebhun
Publikováno v:
The Journal of Cell Biology
The state of actin in the isolated cortex of the unfertilized sea urchin egg can be controlled by experimentally manipulating the pH of the isolation medium. Cortices isolated at the pH of the unfertilized egg (6.5--6.7) do not contain filamentous ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bc8ef6a5cac6a13adb2ae7dc9cd02b
http://europepmc.org/articles/PMC2110437
http://europepmc.org/articles/PMC2110437
Publikováno v:
The Journal of Cell Biology
We have determined the biochemical and immunocytochemical localization of the heterogeneous microtubule-associated protein tau using a monoclonal antibody that binds to all of the tau polypeptides in both bovine and rat brain. Using immunoblot assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533b10a82c66b2d2b43eba2b46bfa761
http://europepmc.org/articles/PMC2113928
http://europepmc.org/articles/PMC2113928
Autor:
Y H Chou, L I Rebhun
Publikováno v:
Journal of Biological Chemistry. 261:5389-5395
The crude actomyosin precipitate from sea urchin (Arbacia punctulata) egg extracts contains Ca2+-sensitive myosin light chain kinase activity. Activity can be further increased by exogenous calmodulin (CaM). Egg myosin light chain kinase activity is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16ed1bbabade15fd70bec5da3867e39f
https://doi.org/10.1016/s0021-9258(19)57228-3
https://doi.org/10.1016/s0021-9258(19)57228-3
Autor:
L. I. Rebhun, G. Sander
Publikováno v:
American Journal of Anatomy. 130:35-53
Eggs of the clam Spisula solidissima were studied by freeze-substitution techniques at the time of the first meiotic division. The mitotic apparatus is organized into regions containing microtubules, endoplasmic reticulum, ribosomes and mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::123b301b25366c719e07d4ff275f4530
https://doi.org/10.1002/aja.1001300104
https://doi.org/10.1002/aja.1001300104
Autor:
L. I. Rebhun, Robert D. Goldman
Publikováno v:
Journal of Cell Science. 4:179-209
The morphology of the isolated sea-urchin mitotic apparatus (MA) was examined by light and electron microscopy. With the polarization microscope and the Nomarski differential interference microscope, the isolated MAs appeared to be similar to in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa99cce2eb1a4d854a4dff07b5b3db4c
https://doi.org/10.1242/jcs.4.1.179
https://doi.org/10.1242/jcs.4.1.179