Zobrazeno 1 - 10
of 40
pro vyhledávání: '"L I, Nikolaeva"'
Autor:
N. G. Yaroslavtseva, D. S. Tikhomirov, L. I. Nikolaeva, A. V. Dedova, E. N. Ovchinnikova, O. N. Misko, T. Yu. Romanova, P. I. Makhnovskiy, A. E. Grishechkin, T. A. Tupoleva
Publikováno v:
Вопросы вирусологии, Vol 64, Iss 1, Pp 30-35 (2019)
Occult HCV infection (OCI) provides significant interest recently. HCV RNA in this case can be detected not in plasma, but in blood cells and/or in liver tissue. In case of antibody genesis impairment anti-HCV detection may lead to negative or “unc
Externí odkaz:
https://doaj.org/article/afca3725cb6d428391c2575ae6264d2e
Autor:
V. V. Koupriyanov, L. I. Nikolaeva, A. A. Zykova, P. I. Makhnovskiy, R. Y. Kotlyarov, A. V. Vasilyev, N. V. Ravin
Publikováno v:
Вопросы вирусологии, Vol 63, Iss 3, Pp 138-143 (2018)
The aim of the study was to investigate immunogenic properties of mosaic recombinant proteins constructed on the data of hepatitis C virus NS4A and NS4B antigens. Four mosaic recombinant proteins, containing the T and B epitopes of the NS4A and NS4B
Externí odkaz:
https://doaj.org/article/29132cb7aeea4773a8396c90e5ff0154
Autor:
E. A. Leybman, L. I. Nikolaeva, G. V. Sapronov, E. I. Samokhvalov, O. B. Kovalev, V. A. Konev, V. F. Uchaikin
Publikováno v:
Детские инфекции (Москва), Vol 16, Iss 4, Pp 17-21 (2017)
The aim of this study was to investigate the clinical and diagnostic significance of the detection of core-antigen of hepatitis C virus (HCV) in children with chronic hepatitis C (CHC). Sera of 101 patients and 24 non-infected participants were analy
Externí odkaz:
https://doaj.org/article/cd048a52f605433db75f18d137ffe198
Autor:
E. A. Mukasheva, L. I. Nikolaeva, P. I. Makhnovsky, E. S. Kirillova, L. V. Kolobukhina, L. N. Merkulova, I. S. Kruzhkova, N. A. Malyshev, E. I. Burtseva
Publikováno v:
Вопросы вирусологии, Vol 62, Iss 3, Pp 109-114 (2017)
Serologic studies occupy a significant place in influenza diagnosis. The article presents an analysis of the developed experimental version of ELISA test-systems for the detection of specific antibodies to the virus influenza A(H1N1)pdm09, and their
Externí odkaz:
https://doaj.org/article/ac52f8cb5864499e8b4abc9b29ca6460
Publikováno v:
Эпидемиология и вакцинопрофилактика, Vol 16, Iss 1, Pp 69-74 (2017)
The aim of this study was to design promising variants of recombinant proteins based on NS4A antigen of hepatitis C virus (HCV) for subsequent work on the creation of a mosaic recombinant vaccine against hepatitis C. Methods. The recombinant proteins
Externí odkaz:
https://doaj.org/article/c16bb4e4d3584e0ba54699f30a468ec1
Effect of Lipid Components on Immunogenicity of Synthetic Fragment of Hepatitis C Virus NS4A Antigen
Autor:
A. N. Belyavtsev, N. S. Shastina, V. V. Kupriyanov, L. I. Nikolaeva, M. V. Melnikova, E. F. Kolesanova, M. Yu. Shimchishina, I. V. Kapustin
Publikováno v:
Russian Journal of Bioorganic Chemistry. 48:621-627
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc15ad98274a5120657607b47a73ecd0
https://doi.org/10.1134/s1068162022030049
https://doi.org/10.1134/s1068162022030049
THE SIGNIFICANCE OF QUANTITIES DETECTION OF СORE ANTIGEN IN BLOOD SERUM OF CHILDREN WITH HEPATITIS C
Autor:
A. Leybman, L. I. Nikolaeva, G. V. Sapronov, E. I. Shestakova, E. I. Samokhvalov, O. B. Kovalev, A. G. Pisarev, L. I. Konovalova, A. E. Grishechkin, V. F. Uchaikin
Publikováno v:
Детские инфекции (Москва), Vol 13, Iss 2, Pp 8-12 (2015)
The clinical and pathogenetic significance of determining HCV core-antigen (HCV core-Ag) in serum of children with hepatitis C was investigated firstly. A direct correlation between the concentration of HCV core-Ag and viral load (VL) was revealed (r
Externí odkaz:
https://doaj.org/article/49d1d7cb94cf4e8799f60ac0c6c2fe6e
Autor:
S. V. Chuelov, E. A. Leybman, T. V. Cherednychenko, A. L. Rossina, L. I. Nikolaeva, E. I. Samokhvalov
Publikováno v:
Детские инфекции (Москва), Vol 12, Iss 4, Pp 27-30 (2015)
The research presents the analysis of the factors of macro-and microorganism facilitating the formation of liver cirrhosis (LC) in CHC in children. 20 patients with liver cirhossis of hepatitis C virus etiology have been observed. No reliable correla
Externí odkaz:
https://doaj.org/article/c3cdfccb62494c20907b09a8232866b2
Publikováno v:
Эпидемиология и вакцинопрофилактика, Vol 14, Iss 3, Pp 23-30 (2015)
Hepatitis C virus (HCV), which was identified in 1989 - 1990. Later it was included in new genus Hepacivirus of the family Flaviviridae. Due the genetic heterogeneity of HCV, viral isolates was decided to classificate on genotypes and sybtypes in acc
Externí odkaz:
https://doaj.org/article/95edab235c414d28be3c7fbda0eceffd
Autor:
E. A. Leybman, L. I. Nikolaeva, E. I. Samokhvalov, K. K. Kyuregayn, O. V. Isaeva, G. V. Sapronov, T. V. Cherednechenko, A. G. Pisarev, A. E. Grishechkin, M. I. Michailov, V. F. Uchaikin
Publikováno v:
Эпидемиология и вакцинопрофилактика, Vol 14, Iss 1, Pp 49-55 (2015)
Hepatitis C is a serious problem for Russian Federation. Determination of HCV genotype/subtype is needed for epidemic control, development of antiviral drugs, vaccines, and planning expenditures for treatment. The aims of the study were to establish
Externí odkaz:
https://doaj.org/article/293f9b893a2743a69acd670ac4bbe35a