Zobrazeno 1 - 10
of 78
pro vyhledávání: '"L Hubler"'
Autor:
M Violet Lee, Scott E Topper, Shane L Hubler, James Hose, Craig D Wenger, Joshua J Coon, Audrey P Gasch
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-12 (2011)
Abstract The transcriptome and proteome change dynamically as cells respond to environmental stress; however, prior proteomic studies reported poor correlation between mRNA and protein, rendering their relationships unclear. To address this, we combi
Externí odkaz:
https://doaj.org/article/b781cc2aee754377a36fca0dc42dfafe
Autor:
Colleen Elizabeth Hayes, Shane L. Hubler, Jerott R. Moore, Lauren E. Barta, Corinne E. Praska, Faye E. Nashold
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
This review summarizes and integrates research on vitamin D and CD4+ T lymphocyte biology to develop new mechanistic insights into the molecular etiology of autoimmune disease. A deep understanding of molecular mechanisms relevant to gene-environment
Externí odkaz:
https://doaj.org/article/71d08dd81c3e43bcb63c5c8c48909fc1
Autor:
Subina Mehta, Pratik D. Jagtap, Praveen Kumar, Timothy J. Griffin, James E. Johnson, Caleb Easterly, Shane L. Hubler
Publikováno v:
Journal of Proteome Research. 19:161-173
Workflows for large-scale (MS)-based shotgun proteomics can potentially lead to costly errors in the form of incorrect peptide-spectrum matches (PSMs). To improve the robustness of these workflows, we have investigated the use of the precursor mass d
Autor:
James R. Johnson, Shane L. Hubler, Joel D. Rudney, Timothy J. Griffin, Pratik D. Jagtap, Ray Sajulga, Subina Mehta, Caleb Easterly, Bart Mesuere, Praveen Kumar
Publikováno v:
MOLECULAR & CELLULAR PROTEOMICS
Microbiome research offers promising insights into the impact of microorganisms on biological systems. Metaproteomics, the study of microbial proteins at the community level, integrates genomic, transcriptomic, and proteomic data to determine the tax
Autor:
Jerott R. Moore, Corwin D. Nelson, Colleen E. Hayes, Faye E. Nashold, Shane L. Hubler, Justin A. Spanier
Publikováno v:
Journal of Neuroimmunology. 324:100-114
We investigated how one calcitriol dose plus vitamin D3 reverses experimental autoimmune encephalomyelitis (EAE), a multiple sclerosis model. This protocol rapidly increased CD4+ T cell Ikzf2 transcripts, Helios protein, and CD4+Helios+FoxP3+ T regul
Autor:
Shiva Kumar Shanmukhappa, Jeffrey S. Huo, Adam A. Margolin, Shane L. Hubler, Punam Malik, Robin Schroll, Carolyn Lutzko, Elias T. Zambidis, James A. Wells, Kenneth Daily, Winston Hide, Christopher N. Mayhew, Stacy Bush, Yuliang Wang, Bruce J. Aronow, Nathan Salomonis, Phillip J. Dexheimer, Mehdi Keddache, Antonis K. Hatzopoulos, Shannan J. Ho Sui, Jose A. Cancelas, Larsson Omberg, Lynn M. Schriml
Publikováno v:
Stem Cell Reports, Vol 7, Iss 1, Pp 110-125 (2016)
Stem Cell Reports
Stem Cell Reports
Summary The rigorous characterization of distinct induced pluripotent stem cells (iPSC) derived from multiple reprogramming technologies, somatic sources, and donors is required to understand potential sources of variability and downstream potential.
Autor:
Jerott R, Moore, Shane L, Hubler, Corwin D, Nelson, Faye E, Nashold, Justin A, Spanier, Colleen E, Hayes
Publikováno v:
Journal of neuroimmunology. 324
We investigated how one calcitriol dose plus vitamin D
Autor:
Thérèse C. Rytz, Marcus J. Miller, Richard D. Vierstra, Lloyd M. Smith, Shane L. Hubler, Mark Scalf
Publikováno v:
Molecular & Cellular Proteomics. 12:449-463
The stress-induced attachment of small ubiquitin-like modifier (SUMO) to a diverse collection of nuclear proteins regulating chromatin architecture, transcription, and RNA biology has been implicated in protecting plants and animals against numerous
Autor:
Michael S. Westphall, Derek J. Bailey, Donald S. Stapleton, Brian S. Yandell, Natalie M. Niemi, Alan D. Attie, Shane L. Hubler, Paul A. Grimsrud, Joshua J. Coon, Adam Jochem, David J. Pagliarini, Joshua J. Carson, Alexander S. Hebert, Mark P. Keller
Publikováno v:
Cell Metabolism. 16(5):672-683
SummaryMitochondria are dynamic organelles that play a central role in a diverse array of metabolic processes. Elucidating mitochondrial adaptations to changing metabolic demands and the pathogenic alterations that underlie metabolic disorders repres
Autor:
Gheorghe Craciun, Shane L. Hubler
Publikováno v:
Journal of Mathematical Chemistry. 50:2446-2470
To count the number of chemical compositions of a particular mass, we consider an alphabet \({\mathop{\bf a}}\) with a mass function which assigns a mass to each letter in \({\mathop{\bf a}}\) . We then compute the mass of a word (an ordered sequence