Zobrazeno 1 - 10
of 701
pro vyhledávání: '"L Herzog"'
Autor:
D Kyburz, C Gabay, A Finckh, C Tellenbach, L Herzog, A Scherer, B Moeller, A Ciurea, I von Muehlenen, L Brulhart, R Müller, P Hasler, P Zufferey
Publikováno v:
RMD Open, Vol 6, Iss 1 (2020)
Background Multiple biologic and targeted synthetic disease-modifying rheumatic drugs (b/tsDMARDs) are approved for the management of rheumatoid arthritis (RA), including TNF inhibitors (TNFi), bDMARDs with other modes of action (bDMARD-OMA) and Janu
Externí odkaz:
https://doaj.org/article/906fd45ef6ec438caabfcd5bb094e2ad
Autor:
Sophia C. Morandi, Elio L. Herzog, Marion Munk, Marco Kreuzer, Carlo R. Largiadèr, Sebastian Wolf, Martin Zinkernagel, Denise C. Zysset-Burri
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background The human gut microbiome (GM) is involved in inflammation and immune response regulation. Dysbiosis, an imbalance in this ecosystem, facilitates pathogenic invasion, disrupts immune equilibrium, and potentially triggers diseases i
Externí odkaz:
https://doaj.org/article/4d7b3210704e4093b71376e158c6a45d
Autor:
Beate Steiner, Christian Leitner, David Stadler, Eva-Maria Prugger, Christoph Magnes, Peter L. Herzog
Publikováno v:
Practical Laboratory Medicine, Vol 40, Iss , Pp e00398- (2024)
Aim: The metabolite α-hydroxybutyrate (α-HB) is an important marker of insulin resistance and impaired glucose tolerance allowing to identify patients at risk of developing diabetes and related metabolic disorders before any symptoms become apparen
Externí odkaz:
https://doaj.org/article/de48c72bc27d41e5b55a3f0756b7ee2f
Publikováno v:
Journal of Orthopaedic Surgery, Vol 12 (2004)
Purpose. To study high-energy phosphates in cortical bone through experiments on inbred white New Zealand rabbits. Methods. Tibial fractures were induced in 80 rabbits and then stabilised by screw osteosynthesis. After 3 (group A; n=40) or 7 days (gr
Externí odkaz:
https://doaj.org/article/8d7428e8fc46453d85cf4d20071aa3d2
Publikováno v:
Journal of Orthopaedic Surgery, Vol 10 (2002)
Purpose. Open lower leg fractures are frequently associated with severe soft tissue damage, followed by osteomyelitis. Using an animal experimental model, we investigated the effect of timing of coverage of a tibial fracture with a local muscle flap.
Externí odkaz:
https://doaj.org/article/924a0a3b4dde4b4888c11ef3c0e6d4e6
Autor:
Livia Spörri, Anne-Christine Uldry, Marco Kreuzer, Elio L. Herzog, Martin S. Zinkernagel, Jan D. Unterlauft, Denise C. Zysset-Burri
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6257 (2024)
Although glaucoma is a leading cause of irreversible blindness worldwide, its pathogenesis is incompletely understood, and intraocular pressure (IOP) is the only modifiable risk factor to target the disease. Several associations between the gut micro
Externí odkaz:
https://doaj.org/article/8470a9edab8747c091bb14b814c11cd3
Autor:
Rachana R. Chandran, Yi Xie, Eunate Gallardo-Vara, Taylor Adams, Rolando Garcia-Milian, Inamul Kabir, Abdul Q. Sheikh, Naftali Kaminski, Kathleen A. Martin, Erica L. Herzog, Daniel M. Greif
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The pluripotency factor KLF4 has been described as pro-fibrotic or anti-fibrotic in various diseases. Herein, the authors show that during lung fibrosis, these distinct effects can be attributed to mesenchymal cell-type specific functions of KLF4.
Externí odkaz:
https://doaj.org/article/bfacbe42ada44a45abedd4f53adc3c31
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Cellular interactions with the extracellular matrix (ECM) play a key role in modulating biological processes. While studies have identified key molecular factors of these interactions, the mechanical regulation associated with these interact
Externí odkaz:
https://doaj.org/article/2a1a073e5be449128718a57ccb25c785
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Distinct patient characteristics have been proposed for ischaemic stroke in the anterior versus posterior circulation. However, data on functional outcome according to stroke territory in patients with acute stroke treatment are conflicting
Externí odkaz:
https://doaj.org/article/84aaadb6ae064dfba8c16e36dd17a8c2
Autor:
Genta Ishikawa, Xueyan Peng, John McGovern, Sam Woo, Carrighan Perry, Angela Liu, Sheeline Yu, Alexander Ghincea, Aliaksandr Kishchanka, Vitória Fiorini, Buqu Hu, Ying Sun, Huanxing Sun, Changwan Ryu, Erica L. Herzog
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L639-L651
Idiopathic pulmonary fibrosis is increasingly associated with nerve-driven processes and endogenous innate immune ligands such as mitochondrial DNA (mtDNA). Interestingly, a connection between these entities has not been explored. Here, we report tha