Zobrazeno 1 - 10
of 273
pro vyhledávání: '"L Hageman"'
Autor:
M. A. Zouache, B. T. Richards, C. M. Pappas, R. A. Anstadt, J. Liu, T. Corsetti, S. Matthews, N. A. Seager, S. Schmitz-Valckenberg, M. Fleckenstein, W. C. Hubbard, J. Thomas, J. L. Hageman, B. L. Williams, G. S. Hageman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Dysregulation of the alternative pathway (AP) of the complement system is a significant contributor to age-related macular degeneration (AMD), a primary cause of irreversible vision loss worldwide. Here, we assess the contribution of the liv
Externí odkaz:
https://doaj.org/article/5509274071cb4770a0b493d6e99eb582
Autor:
Mohammed Ghiboub, Jan Koster, Peter D. Craggs, Andrew Y. F. Li Yim, Anthony Shillings, Sue Hutchinson, Ryan P. Bingham, Kelly Gatfield, Ishtu L. Hageman, Gang Yao, Heather P. O’Keefe, Aaron Coffin, Amish Patel, Lisa A. Sloan, Darren J. Mitchell, Thomas G. Hayhow, Laurent Lunven, Robert J. Watson, Christopher E. Blunt, Lee A. Harrison, Gordon Bruton, Umesh Kumar, Natalie Hamer, John R. Spaull, Danny A. Zwijnenburg, Olaf Welting, Theodorus B. M. Hakvoort, Anje A. te Velde, Johan van Limbergen, Peter Henneman, Rab K. Prinjha, Menno P. J. de Winther, Nicola R. Harker, David F. Tough, Wouter J. de Jonge
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-27 (2022)
Abstract Background SP140 is a bromodomain-containing protein expressed predominantly in immune cells. Genetic polymorphisms and epigenetic modifications in the SP140 locus have been linked to Crohn’s disease (CD), suggesting a role in inflammation
Externí odkaz:
https://doaj.org/article/9421aa4ae34c4942a0bffbd856768807
Autor:
Chris M. Pappas, Moussa A. Zouache, Stacie Matthews, Caitlin D. Faust, Jill L. Hageman, Brandi L. Williams, Burt T. Richards, Gregory S. Hageman
Publikováno v:
Human Genomics, Vol 15, Iss 1, Pp 1-15 (2021)
Abstract Background Single-variant associations with age-related macular degeneration (AMD), one of the most prevalent causes of irreversible vision loss worldwide, have been studied extensively. However, because of a lack of refinement of these asso
Externí odkaz:
https://doaj.org/article/b770e6f69a7d40b394cde71ed55256da
Autor:
Manon de Krijger, Ishtu L. Hageman, Andrew Y. F. Li Yim, Jan Verhoeff, Juan J. Garcia Vallejo, Patricia H. P. van Hamersveld, Evgeni Levin, Theodorus B. M. Hakvoort, Manon E. Wildenberg, Peter Henneman, Cyriel Y. Ponsioen, Wouter J. de Jonge
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPrimary sclerosing cholangitis (PSC) is a chronic inflammatory liver disease affecting the intra- and extrahepatic bile ducts, and is strongly associated with ulcerative colitis (UC). In this study, we explored the peripheral blood DNA meth
Externí odkaz:
https://doaj.org/article/ecb2a98c38e74c07ac01f6e645bbf90b
Autor:
Ahmed M. I. Elfiky, Ishtu L. Hageman, Marte A. J. Becker, Jan Verhoeff, Andrew Y. F. Li Yim, Vincent W. Joustra, Lieven Mulders, Ivan Fung, Inmaculada Rioja, Rab K. Prinjha, Nicholas N. Smithers, Rebecca C. Furze, Palwinder K. Mander, Matthew J. Bell, Christianne J. Buskens, Geert R. D’Haens, Manon E. Wildenberg, Wouter J. de Jonge
Publikováno v:
Cells, Vol 11, Iss 18, p 2846 (2022)
Background: Myeloid cells are critical determinants of the sustained inflammation in Crohn’s Disease (CD). Targeting such cells may be an effective therapeutic approach for refractory CD patients. Bromodomain and extra-terminal domain protein inhib
Externí odkaz:
https://doaj.org/article/006cf9b280ac4952bda401939457b659
Autor:
Vincent W. Joustra, Andrew Y. F. Li Yim, Jessica R. de Bruyn, Marjolijn Duijvestein, Ishtu L. Hageman, Wouter J. de Jonge, Peter Henneman, Manon Wildenberg, Geert D’Haens
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10467 (2022)
Prediction of endoscopic post-operative recurrence (POR) in Crohn’s disease (CD) patients following ileocolonic resection (ICR) using clinical risk factors alone has thus far been inadequate. While peripheral blood leukocyte (PBL) DNA methylation h
Externí odkaz:
https://doaj.org/article/7db02ab23c0c44aea4813b64d0c0967d
Autor:
Moussa A. Zouache, Alex Bennion, Jill L. Hageman, Christian Pappas, Burt T. Richards, Gregory S. Hageman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/d705d2137905443487362e8861dc4ddb
Autor:
W. Huisman, M. C. J. Roex, L. Hageman, E. A. S. Koster, S. A. J. Veld, C. Hoogstraten, P. van Balen, H. M. van Egmond, C. A. M. van Bergen, H. Einsele, L. Germeroth, D. Amsen, J. H. F. Falkenburg, I. Jedema
Publikováno v:
Blood advances, 7(5), 812-827. American Society of Hematology
Adoptive cellular therapies with T cells are increasingly used to treat a variety of conditions. For instance, in a recent phase 1/2 trial, we prophylactically administered multivirus-specific T-cell products to protect recipients of T-cell–deplete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfa91810cbb072d6f5015de5688f40a
https://pure.amc.nl/en/publications/tracking-the-progeny-of-adoptively-transferred-virusspecific-t-cells-in-patients-posttransplant-using-tcr-sequencing(9d44c25f-7adc-422d-bb70-a36d15c2d289).html
https://pure.amc.nl/en/publications/tracking-the-progeny-of-adoptively-transferred-virusspecific-t-cells-in-patients-posttransplant-using-tcr-sequencing(9d44c25f-7adc-422d-bb70-a36d15c2d289).html
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