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Two distinct nuclear transcription factors recognize loop and bulge residues of the HIV-1 TAR RNA hairpin

Autor: L H Milocco, Katherine A. Jones, Christian T. Sheline

Publikováno v: Genes & Development. 5:2508-2520

Transcriptional activation by the HIV-1 Tat protein requires specific residues in the hexanucleotide loop and trinucleotide bulge of the TAR RNA stem-loop structure found in the 5'-untranslated leader of all viral transcripts. Tat directly contacts r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7e505c613a647f512849becac385bd
https://doi.org/10.1101/gad.5.12b.2508

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STAT protein complexes activated by interferon-gamma and gp130 signaling molecules differ in their sequence preferences and transcriptional induction properties

Autor: L H Milocco, Linda Kessler, J Haslam, P Lamb, Jeffrey Rosen, H M Seidel, R.B. Stein

Publikováno v: Nucleic acids research. 23(16)

Activation of members of the STAT (signal transducers and activators of transcription) family of latent transcription factors is an early event following the binding of many cytokines to their cognate receptors. Although the patterns of STATs activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ec614df655da6ef58af014570c824c
https://pubmed.ncbi.nlm.nih.gov/7667105

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Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity

Autor: Jon Rosen, P Lamb, J E Darnell, R.B. Stein, H M Seidel, L H Milocco

Signal transducers and activators of transcription (STAT proteins) bind to palindromic sequence elements related to interferon gamma (IFN-gamma) activation sites, which were first identified in the promoters of IFN-gamma-inducible genes. Although the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c341e762742e51e6574f3d87b520d307
https://europepmc.org/articles/PMC42355/

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