Zobrazeno 1 - 10
of 83
pro vyhledávání: '"L H Glimcher"'
Publikováno v:
The Journal of Immunology. 159:5914-5920
Class II MHC molecules are heterodimeric transmembrane glycoproteins that function in the presentation of Ag to CD4+ T cells. Deletion of the cytoplasmic domains of the murine class II A alpha- and A beta-chains has previously been shown to diminish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffa21b7819813b4b9fc1a10fc457e041
https://doi.org/10.4049/jimmunol.159.12.5914
https://doi.org/10.4049/jimmunol.159.12.5914
Publikováno v:
The Journal of Immunology. 158:4741-4749
The MHC class II transactivator gene (CIITA) coordinately controls the expression of the three major human class II genes, HLA-DR, HLA-DQ, and HLA-DP. Indeed, patients with one form of MHC class II immunodeficiency disease, due to defective CIITA gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d02c71f4256676740e5ae0a0d2eb707
https://doi.org/10.4049/jimmunol.158.10.4741
https://doi.org/10.4049/jimmunol.158.10.4741
Publikováno v:
The Journal of Immunology. 156:3821-3827
Many tumor cells that have been transfected with genes encoding B7 costimulatory molecules become effective cellular vaccines against wild-type tumor. The improved immunity is dependent on newly induced tumor-specific CD8+ and/or CD4+ T cells and pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d941ed048209cc0ab2cface1b3ffff38
https://doi.org/10.4049/jimmunol.156.10.3821
https://doi.org/10.4049/jimmunol.156.10.3821
Publikováno v:
The Journal of Immunology. 154:6397-6405
Immune responses to pathogens often lead to the generation of polarized T helper subsets designated Th1 and Th2. Th1 cells, characterized by the production of IL-2 and IFN-gamma, stimulate cellular immune responses important for protection against in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23706497e98518c1b018dde41ed6e7e5
https://doi.org/10.4049/jimmunol.154.12.6397
https://doi.org/10.4049/jimmunol.154.12.6397
Publikováno v:
The Journal of Immunology. 153:4853-4861
The ability of the staphylococcal enterotoxins to stimulate T cells has been thought to depend on their association with class II MHC products. Here, we demonstrate that a subgroup of staphylococcal enterotoxins, which includes staphylococcal enterot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2517e4f866176a02601cbbee098e2fbf
https://doi.org/10.4049/jimmunol.153.11.4853
https://doi.org/10.4049/jimmunol.153.11.4853
Publikováno v:
The Journal of Immunology. 152:3254-3263
Recent evidence suggests that I-E+ thymic epithelium, especially medullary epithelium, can induce partial deletion of superantigen-reactive T cells expressing TcR V beta 5, V beta 11, and V beta 17. To seek further information on this issue, we const
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3380e183f77715ea3fedf8ea0cb9e3c4
https://doi.org/10.4049/jimmunol.152.7.3254
https://doi.org/10.4049/jimmunol.152.7.3254
Publikováno v:
The Journal of Immunology. 152:77-86
We have examined the transcriptional regulation of the Th1-specific IL-2 gene and the Th2-specific IL-4 gene by transient transfection of promoter-chloramphenicol acetyl transferase (CAT) constructs into T cell clones and by electrophoretic mobility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf6f03fe24c54544feb8a2d8b496b24
https://doi.org/10.4049/jimmunol.152.1.77
https://doi.org/10.4049/jimmunol.152.1.77
Autor:
M Bigby, J S Markowitz, P A Bleicher, M J Grusby, S Simha, M Siebrecht, M Wagner, C Nagler-Anderson, L H Glimcher
Publikováno v:
The Journal of Immunology. 151:4465-4475
MHC class I and class II molecules are essential for intrathymic maturation of a normal repertoire of alpha beta T cells. The development of gamma delta T cells may similarly require exposure to conventional MHC or MHC-like molecules for appropriate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58f4726e7dd5205e76d5c86951f3934f
https://doi.org/10.4049/jimmunol.151.9.4465
https://doi.org/10.4049/jimmunol.151.9.4465
Publikováno v:
The Journal of Immunology. 151:4173-4182
Transforming growth factor beta 1 (TGF-beta 1) is a pleiotropic cytokine that decreases the expression of class II MHC Ag in the melanoma cell line Hs294T(c). To investigate the mechanism of this repression, we have examined the effect of TGF-beta 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::091df3824a02c06129bae3dfa72e03db
https://doi.org/10.4049/jimmunol.151.8.4173
https://doi.org/10.4049/jimmunol.151.8.4173
Autor:
C J Kara, L H Glimcher
Publikováno v:
The Journal of Immunology. 150:4934-4942
The class II genes of the major histocompatibility complex are a family of genes whose expression is regulated developmentally in cells of the B lineage and by IFN-gamma in many other cell types. Using the approach of in vivo footprinting, which allo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f1094831a60d1dbbda755e6b0af0dfe
https://doi.org/10.4049/jimmunol.150.11.4934
https://doi.org/10.4049/jimmunol.150.11.4934