Zobrazeno 1 - 10
of 17
pro vyhledávání: '"L H, Philipson"'
Autor:
I. D. Dukes, L. H. Philipson
Publikováno v:
Diabetes. 45:845-853
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::584ee7c375aa1d89fe5a6384156ee84f
https://doi.org/10.2337/diabetes.45.7.845
https://doi.org/10.2337/diabetes.45.7.845
Publikováno v:
Pediatric diabetes. 14(2)
Recent results of genome wide association study (GWAS) for diabetes genes, while reaching impressive technical milestones and implicating new findings for research, have been uniformly disappointing in terms of immediate clinical utility. The relativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b79527f522a9bc94288caae7b8d5ca76
https://pubmed.ncbi.nlm.nih.gov/23350725
https://pubmed.ncbi.nlm.nih.gov/23350725
Autor:
D A, Jacobson, L H, Philipson
Publikováno v:
Handbook of experimental pharmacology. (179)
Orchestrated ion fluctuations within pancreatic islets regulate hormone secretion and maybe essential to processes such as apoptosis. A diverse set of ion channels allows for islet cells to respond to a variety of signals and dynamically regulate hor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f948920c00f72f5e4f5d3baefcf5ba4
https://pubmed.ncbi.nlm.nih.gov/17217070
https://pubmed.ncbi.nlm.nih.gov/17217070
Autor:
Christopher J. Rhodes, L H Philipson, J M Edwardson, B Wicksteed, J F McCuaig, Lori B. Hays, Y Wang
Publikováno v:
The Journal of endocrinology. 185(1)
Several proteins play a role in the mechanism of insulin exocytosis. However, these ‘exocytotic proteins’ have yet to account for the regulated aspect of insulin exocytosis, and other factors are involved. In pancreatic exocrine cells, the intral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0a061949d09f48479869e769af6e1d
https://pubmed.ncbi.nlm.nih.gov/15817827
https://pubmed.ncbi.nlm.nih.gov/15817827
Autor:
L H, Philipson
Publikováno v:
The Journal of allergy and clinical immunology. 110
This review presents recent concepts of how beta-agonists affect glucose homeostasis by modulating insulin secretion, liver metabolism, and uptake of glucose into muscle, with attention to the influence of hypoglycemia on beta-agonist sensitivity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fdc48fb8154acebe651dc6bbc7ed5579
https://pubmed.ncbi.nlm.nih.gov/12464941
https://pubmed.ncbi.nlm.nih.gov/12464941
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(2)
We examined the ability of rat Y1, Y2 and Y4 neuropeptide Y (NPY) receptors to regulate K+ and Ca++ channels expressed in Xenopus oocytes and HEK 293 cells, respectively. Stimulation of all three receptors with NPY or related peptides activated inwar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12e2250866eb9261bf6b6c3ef0616d43
https://pubmed.ncbi.nlm.nih.gov/9454807
https://pubmed.ncbi.nlm.nih.gov/9454807
Autor:
M W, Roe, J F, Worley, A A, Mittal, A, Kuznetsov, S, DasGupta, R J, Mertz, S M, Witherspoon, N, Blair, M E, Lancaster, M S, McIntyre, W R, Shehee, I D, Dukes, L H, Philipson
Publikováno v:
The Journal of biological chemistry. 271(50)
Voltage-dependent delayed rectifier K+ channels regulate aspects of both stimulus-secretion and excitation-contraction coupling, but assigning specific roles to these channels has proved problematic. Using transgenically derived insulinoma cells (bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::723326b060f01dedebfff1b11c2ad0bc
https://pubmed.ncbi.nlm.nih.gov/8943282
https://pubmed.ncbi.nlm.nih.gov/8943282
Publikováno v:
Receptorschannels. 4(4)
The alpha 1E voltage-dependent calcium channel has not been clearly identified with a specific neuronal calcium current. To help identify the role of alpha 1E, we examined differential expression of alpha 1E splice variants in mouse brain and culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08ad17a000b18f98fc75f586f8bd5576
https://pubmed.ncbi.nlm.nih.gov/9065972
https://pubmed.ncbi.nlm.nih.gov/9065972
Publikováno v:
Molecular pharmacology. 47(5)
cRNAs encoding the kappa-opioid receptor and an inwardly rectifying, G protein-coupled, K+ channel were coinjected into Xenopus oocytes. The effects of kappa-opioid receptor agonists and antagonists on the membrane currents in these oocytes were stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0276087e19410a5e111749a307c43be
https://pubmed.ncbi.nlm.nih.gov/7746270
https://pubmed.ncbi.nlm.nih.gov/7746270
Publikováno v:
Molecular pharmacology. 47(1)
The effect of clofilium on potassium conductance was studied in excised membrane patches from Chinese hamster ovary cells stably transfected with the Kv1.5/hPCN1 delayed rectifier K+ channel gene. Bath application of clofilium resulted in current inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58e453a49894675b1aa3d01309350a02
https://pubmed.ncbi.nlm.nih.gov/7838129
https://pubmed.ncbi.nlm.nih.gov/7838129