Zobrazeno 1 - 10
of 155
pro vyhledávání: '"L H, Brown"'
This book reviews recently developed theoretical and numerical approaches to deal with optical and mechanical signals from individual molecules. The character of data generated by single molecules, and more generally by single nano-objects, qualitati
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Dynamic processes on membrane surfaces are essential for biological function. Traditionally, quantitative measurements of lipid/protein motion have been interpreted in the framework of membrane hydrodynamics. However, some recent single-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c044d83f78b1eaba8203b4b43d24e0
https://doi.org/10.1073/pnas.2113202118
https://doi.org/10.1073/pnas.2113202118
Publikováno v:
The Journal of Chemical Physics. 158:044112
Recent single-molecule measurements [Schoch et al., Proc. Natl. Acad. Sci. U. S. A. 118, e2113202118 (2021)] have observed dynamic lipid–lipid correlations in membranes with submicrometer spatial resolution and submillisecond temporal resolution. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::221aba58c99b2027caffb6c5dce36fc1
https://doi.org/10.1063/5.0129130
https://doi.org/10.1063/5.0129130
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69436 (2013)
The repulsive interaction between oppositely charged macroions is investigated using Grand Canonical Monte Carlo simulations of an unrestricted primitive model, including the effect of inhomogeneous surface charge and its density, the depth of surfac
Externí odkaz:
https://doaj.org/article/0aa50e48f880442081e3c81401e4bc35
Publikováno v:
The Journal of Physical Chemistry B. 122:1112-1120
A detailed analysis is carried out on both published experimental results and new experiments for the methylation kinetics of two-site DNA substrates (with site separations between 100 and 800 bp) catalyzed by bacterial DNA adenine methyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195b38a48fe57df98c7c824c1aae671e
https://doi.org/10.1021/acs.jpcb.7b10349
https://doi.org/10.1021/acs.jpcb.7b10349
Publikováno v:
Chemistry and Physics of Lipids. 192:60-74
Lipid areas (Aℓ), bilayer area compressibilities (KA), bilayer bending constants (KC), and monolayer spontaneous curvatures (c0) from simulations using the CHARMM36 force field are reported for 12 representative homogenous lipid bilayers. Aℓ (or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4912a141a2f812d106b17e83c51867
https://doi.org/10.1016/j.chemphyslip.2015.07.014
https://doi.org/10.1016/j.chemphyslip.2015.07.014
Publikováno v:
The Journal of Physical Chemistry B. 118:8420-8432
The aggregation of peptides on a lipid bilayer is studied using coarse-grained molecular dynamics in implicit solvent. Peptides bind to and self-assemble on the membrane surface into β-rich fibrillar aggregates, even under conditions where only diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f261d452c075df3817e52a74394e3fa8
https://doi.org/10.1021/jp502871m
https://doi.org/10.1021/jp502871m
Autor:
Frank L. H. Brown, Brian A. Camley
Publikováno v:
The Journal of Chemical Physics. 151:124104
An interfacial regularized Stokeslet scheme is presented to predict the motion of solid bodies (e.g. proteins or gel-phase domains) embedded within flowing lipid bilayer membranes. The approach provides a numerical route to calculate velocities and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a469813472b48262072914de4320c4f
https://doi.org/10.1063/1.5121418
https://doi.org/10.1063/1.5121418
Publikováno v:
The Journal of Chemical Physics. 150:244120
Recently derived steady-state differential rate laws for the catalytic turnover of molecules containing two substrate sites are reformulated as integrated rate laws. The analysis applies to a broad class of Markovian dynamic models, motivated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4f6a5bf5daf775d0d7d3fbcef6b1c8
https://doi.org/10.1063/1.5097576
https://doi.org/10.1063/1.5097576
Publikováno v:
Journal of Computational Physics. 252:65-85
Biological membranes contain many types of embedded proteins whose collective organization and functions depend importantly on the mechanical interplay with the lipid bilayer. We introduce new methods at the level of individual proteins embedded with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc4bb0138f0fb51150dbda0d045e3180
https://doi.org/10.1016/j.jcp.2013.06.016
https://doi.org/10.1016/j.jcp.2013.06.016