Zobrazeno 1 - 10
of 36
pro vyhledávání: '"L G Littlefield"'
Autor:
D. Blakey, A. T. Natarajan, L. G. Littlefield, W. F. Morgan, James D. Tucker, Michael N. Cornforth, C. Shasserre, M. Bauchinger, A. A. Awa
Publikováno v:
Cytogenetic and Genome Research. 68:211-221
The advent of chromosome painting has brought the realization that structural aberrations can be far more complicated than previously imagined. Various investigators have devised their own nomenclature systems to deal with this difficulty, with the r
Autor:
E. D. Thompson, J. L. Seymour, M. J. Aardema, R. A. Leboeuf, B. L. B. Evans, D. B. Cody, L. G. Littlefield
Publikováno v:
Environmental and Molecular Mutagenesis. 18:184-199
Three cross-linked polyacrylate polymers containing either methylenebis-acrylamide (MBA), trimethylolpropane triacrylate (TMPTA), or triallylamine (TAA) cross-linkers were tested for genotoxicity with the Salmonella mammalian microsome assay, the L51
Publikováno v:
Environmental and Molecular Mutagenesis. 17:152-154
The nitrosourea mustard MeCCNU is the most recent organic chemical to be classified as a human carcinogen by IARC. MeCCNU gave a strong positive response when tested in the mouse bone marrow micronucleus assay. Activity was evident using either ip in
Publikováno v:
Environmental and molecular mutagenesis. 33(2)
The induction, distribution, and persistence of chromosome aberrations in human lymphocytes exposed to X-rays in G0 were analyzed in 48-, 70-, and 94-hr cultures by conventional metaphase analysis and painting of chromosomes 1, 2, and 4 by FISH. All
Autor:
N, Nakamura, J D, Tucker, M, Bauchinger, L G, Littlefield, D C, Lloyd, R J, Preston, M S, Sasaki, A A, Awa, S, Wolff
Publikováno v:
Radiation research. 150(4)
Autor:
L G, Littlefield, A F, McFee, S I, Salomaa, J D, Tucker, P D, Inskip, A M, Sayer, C, Lindholm, S, Mäkinen, R, Mustonen, K, Sorensen, M, Tekkel, T, Veidebaum, A, Auvinen, J D, Boice
Publikováno v:
Radiation research. 150(2)
Studies of workers who were sent to Chernobyl after the 1986 reactor accident are being conducted to provide a better understanding of the effects of chronic low-dose radiation exposures. A crucial component to these investigations is an accurate ass
Publikováno v:
Radiation research. 148(2)
Thorotrast, a colloidal suspension of the long-lived radionuclide, thorium-232, was widely used as a radiographic contrast medium for several decades. Due to the poor excretion of the sol, however, Thorotrast would deposit in the liver, bone marrow a
Autor:
P D, Inskip, M F, Hartshorne, M, Tekkel, M, Rahu, T, Veidebaum, A, Auvinen, L A, Crooks, L G, Littlefield, A F, McFee, S, Salomaa, S, Makinen, J D, Tucker, K J, Sorensen, W L, Bigbee, J D, Boice
Publikováno v:
Radiation research. 147(2)
Thyroid examinations, including palpation, ultrasound and, selectively, fine-needle aspiration biopsy, were conducted on nearly 2,000 Chernobyl cleanup workers from Estonia to evaluate the occurrence of thyroid cancer and nodular thyroid disease amon
Publikováno v:
Environmental and molecular mutagenesis. 29(1)
Procedures are described for the in vitro culture of human lymphocytes, which have been concentrated by density gradient centrifugation, and for a modified slide-making technique for the fixed cells. The method yields improved percentages of mitotic
Publikováno v:
IARC scientific publications. (142)
Cytogenetic end-points have been successfully used in epidemiological studies for many years. Conventional end-points are now being replaced by procedures that utilize molecular methods, with greatly increased sensitivity, specificity and precision.