Zobrazeno 1 - 6 of 6 pro vyhledávání: '"L G, Remsen"'
1
First evidence of otoprotection against carboplatin-induced hearing loss with a two-compartment system in patients with central nervous system malignancy using sodium thiosulfate
Autor: E A, Neuwelt, R E, Brummett, N D, Doolittle, L L, Muldoon, R A, Kroll, M A, Pagel, R, Dojan, V, Church, L G, Remsen, J S, Bubalo
Publikováno v: The Journal of pharmacology and experimental therapeutics. 286(1)
Sodium thiosulfate (STS) provides protection against carboplatin-induced ototoxicity in an animal model. The purpose of this study was to determine the STS dose required for otoprotection, in patients with malignant brain tumors treated with carbopla
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b73259271638e35d2eea9fc990d683af
https://pubmed.ncbi.nlm.nih.gov/9655844
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2
Differential permeability of a human brain tumor xenograft in the nude rat: impact of tumor size and method of administration on optimizing delivery of biologically diverse agents
Autor: E A, Neuwelt, P A, Barnett, C I, McCormick, L G, Remsen, R A, Kroll, G, Sexton
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 4(6)
To assess how to maximize drug delivery to intracerebral tumors and surrounding brain, this study examined the effects of route and method of administration and tumor size on the distribution of three agents in a nude rat intracerebral tumor xenograf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94d637bc55dd6bdd3e3322e92468e009
https://pubmed.ncbi.nlm.nih.gov/9626476
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3
MR of carcinoma-specific monoclonal antibody conjugated to monocrystalline iron oxide nanoparticles: the potential for noninvasive diagnosis
Autor: L G, Remsen, C I, McCormick, S, Roman-Goldstein, G, Nilaver, R, Weissleder, A, Bogdanov, I, Hellström, R A, Kroll, E A, Neuwelt
Publikováno v: AJNR Am J Neuroradiol
PURPOSE: To determine if tumor-specific monoclonal antibodies conjugated to superparamagnetic monocrystalline iron oxide nanoparticles can be used to yield specific diagnoses with the use of MR imaging. METHODS: Monoclonal antibodies conjugated to mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f91bc9f9cc5b1855c2c0e0bde0627db8
https://pubmed.ncbi.nlm.nih.gov/8881233
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4
In vitro and animal studies of sodium thiosulfate as a potential chemoprotectant against carboplatin-induced ototoxicity
Autor: E A, Neuwelt, R E, Brummett, L G, Remsen, R A, Kroll, M A, Pagel, C I, McCormick, S, Guitjens, L L, Muldoon
Publikováno v: Cancer research. 56(4)
When carboplatin (cis-diammine-1,1-cyclobutane-dicarboxylato-platinum) delivery to brain tumors is optimized with osmotic blood-brain barrier disruption (BBBD), high frequency hearing loss can result. Treatment with sodium thiosulfate (STS) blocked c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf150c32e9542465a6de8533ddf951e0
https://pubmed.ncbi.nlm.nih.gov/8630999
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5
Decreased delivery and acute toxicity of cranial irradiation and chemotherapy given with osmotic blood-brain barrier disruption in a rodent model: the issue of sequence
Autor: L G, Remsen, C I, McCormick, G, Sexton, H D, Pearse, R, Garcia, E A, Neuwelt
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 1(7)
The sequence of chemotherapy administered prior to cranial irradiation rather than the more traditional order of radiation followed by chemotherapy is currently being evaluated. This rodent study was designed to assess the sequencing of radiation the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3640a49f940b2e83d123780838a71599
https://pubmed.ncbi.nlm.nih.gov/9816039
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