Zobrazeno 1 - 10
of 76
pro vyhledávání: '"L G, Magazanik"'
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 102(6)
The intracranial EEG was continuously registered in Krushinskii-Molodkina rats with inherited susceptibility to audiogenic seizures and in Wistar rats, which are resistant to the audiogenic convulsions in the lithium-pilocarpine model of status epile
Autor:
E. E. Nikol’skii, L. G. Magazanik
Publikováno v:
Herald of the Russian Academy of Sciences. 80:208-215
Autor:
D S, Vasiliev, N L, Tumanova, I A, Zhuravin, K Kh, Kim, N Ya, Lukomskaya, L G, Magazanik, A V, Zaitsev
Publikováno v:
Zhurnal evoliutsionnoi biokhimii i fiziologii. 50(6)
Animal models of epilepsy are very diverse and are used to elucidate the mechanisms underlying epileptogenesis and seizures. A single administration of pentylenetetrazole (PTZ) induces seizures, however it does not increase risk of further developmen
Autor:
D S, Vasil'ev, N L, Tumanova, V V, Lavrent'eva, L A, Starshinova, E P, Zhabko, N Ia, Lukomskaia, I A, Zhuravin, L G, Magazanik
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 99(9)
We investigated in mice the relationship between convulsions and morphological changes of hippocampal neurons that arise in the development of pentylentetrazol (PTZ)-induced kindling. The kindling was caused by of 35 mg/kg PTZ i.p. 3 times a week for
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 99(5)
The action of non-competitive glutamate receptor antagonists on the effects of sleep deprivation has been studied on Krushinskii-Molodkina rats having an inherited predisposition to audiogenic seizures and Wistar rats deprived to this respond. Two ty
Autor:
K Kh, Kim, A V, Zaĭtsev, V V, Lavrent'eva, E P, Zhabko, S I, Vataev, N Ia, Lukomskaia, L G, Magazanik
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 98(12)
Krushinsky-Molodkina (KM) rats exhibit inherited susceptibility to audiogenic seizures and auditory stimuli induce generalized tonic-clonic seizures that resemble human epilepsy. The aim of this study was to compare the neurological manifestations of
Autor:
L. G. Magazanik
Publikováno v:
Journal of Toxicology: Toxin Reviews. 15:59-76
Progress in the investigation of glutamate receptors structure and function requires the use of specific chemical tools affecting the responses to glutamate and other excitatory amino acids. Several low molecular weight spider and wasp toxins may be
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 98(4)
The action of noncompetitive blockers of glutamate receptors has been investigated on Krushinski-Molodkina rats genetically-prone to audiogenic seizures. The selective blockers of NMDA receptor channels, memantine and IEM-1921, and their dicationic h
Autor:
D B, Tikhonov, L G, Magazanik
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 96(7)
Dysfunctions of glutamatergic synaptic neurotransmission often accompany various CNS disorders. Action of excessive glutamate, which causes excitotoxic effects by neuron depolarization and massive calcium influx can lead to cell death. Despite obviou
Autor:
D B, Tikhonov, L G, Magazanik
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 94(9)
A review of the main approaches to the revealing molecular evolution of glutamate receptors is presented. Large amount of evidences concerning the homology of glutamate-binding proteins forming the membrane channels has been accumulated. However, the