Zobrazeno 1 - 10
of 31
pro vyhledávání: '"L G, Lomax"'
Publikováno v:
Biomaterials. 21:1947-1957
The implantation of biomaterials elicits a host response that influences the long-term behavior of implanted medical devices. This foreign body response is governed by cells of the immune system. Because sexual dimorphism in the immune system is well
Publikováno v:
Environmental and Molecular Mutagenesis. 35:336-342
In this study, the rodent air pouch model was used to examine the production and processing of oxidative DNA damage in two strains of rats commonly used in toxicity testing. An inflammatory response was induced by injecting zymosan A (50 mg) into an
Publikováno v:
International Journal of Toxicology. 17:1-22
These studies were conducted to evaluate the potential for repeated subchronic administration of triethylene glycol monomethyl ether (TGME) to produce systemic toxicity in the rat following dermal application, and neurotoxicity in the rat following p
Autor:
Victor J. Feron, L. G. Lomax, Josje H.E. Arts, M. H. M. Kuijpers, C.F. Kuper, P.G.J. Reuzel, C. Gembardt, E. Löser
Publikováno v:
Toxicological Sciences. 22:195-210
Four groups of 60 Wistar rats of each sex were exposed by inhalation to 0, 0.2, 1.0, or 6.0 mg/m3 respirable polymeric methylene diphenyl diisocyanate (polymeric MDI) aerosol (93.5% < 4.2 microns) for 6 hr a day, 5 days a week for up to 24 months. In
Publikováno v:
Neurotoxicology and Teratology. 15:313-326
Large evoked potential and EEG changes occurred in a pilot study in Fischer 344 rats during exposure to 2000 ppm of 1,1,1-trichloroethane (1,1,1-T; a cleaning solvent with anesthetic properties). In the main study, rats were evaluated for persistent
Autor:
R.R. Miller, D. A. Dittenber, L. G. Lomax, J. E. Phillips, William J. Breslin, Michael J. Bartels, L. L. Calhoun
Publikováno v:
Fundamental and Applied Toxicology. 17:466-481
Studies were conducted to characterize the hemolytic effects of EGPE in rabbits following oral and dermal exposure, and to evaluate the in vitro hemolytic potential of EGPE and its major metabolite using rabbit red blood cells (RBC). Gavage administr
Publikováno v:
American Industrial Hygiene Association Journal. 52:192-197
4-Phenylcyclohexene (4-PCH) is a by-product formed in trace amounts during the production of styrene-butadiene latexes, which are used in carpet manufacturing. The dermal sensitization potential of 4-PCH was evaluated by using a modification of the B
Autor:
W. J. BRESLIN, J. E. PHILLIPS, L. G. LOMAX, M. J. BARTELS, D. A. DITTENBER, L. L. CALHOUN, R. R. MILLER
Publikováno v:
Toxicological Sciences. 17:466-481
Publikováno v:
Environmental and molecular mutagenesis. 35(4)
In this study, the rodent air pouch model was used to examine the production and processing of oxidative DNA damage in two strains of rats commonly used in toxicity testing. An inflammatory response was induced by injecting zymosan A (50 mg) into an
Autor:
W J, Breslin, J E, Phillips, L G, Lomax, M J, Bartels, D A, Dittenber, L L, Calhoun, R R, Miller
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 17(3)
Studies were conducted to characterize the hemolytic effects of EGPE in rabbits following oral and dermal exposure, and to evaluate the in vitro hemolytic potential of EGPE and its major metabolite using rabbit red blood cells (RBC). Gavage administr