Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously

Autor: S W, Dow, L G, Fradkin, D H, Liggitt, A P, Willson, T D, Heath, T A, Potter

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(3)

Cationic lipid-DNA complexes (CLDC) are reported to be safe and effective for systemic gene delivery, particularly to the lungs. However, we observed that i.v. injection of CLDC induced immunologic effects not previously reported. We found that even

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9f1a4b6afe657056f733abe8ba9a0f1b
https://pubmed.ncbi.nlm.nih.gov/10415059

Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys.

Autor: Abbink, Peter¹ (AUTHOR), Larocca, Rafael A.¹ (AUTHOR), De La Barrera, Rafael A.² (AUTHOR), Bricault, Christine A.¹ (AUTHOR), Moseley, Edward T.¹ (AUTHOR), Boyd, Michael¹ (AUTHOR), Kirilova, Marinela¹ (AUTHOR), Zhenfeng Li¹ (AUTHOR), Ng’ang’a, David¹ (AUTHOR), Nanayakkara, Ovini¹ (AUTHOR), Nityanandam, Ramya¹ (AUTHOR), Mercado, Noe B.¹ (AUTHOR), Borducchi, Erica N.¹ (AUTHOR), Agarwal, Arshi¹ (AUTHOR), Brinkman, Amanda L.¹ (AUTHOR), Cabral, Crystal¹ (AUTHOR), Chandrashekar, Abishek¹ (AUTHOR), Giglio, Patricia B.¹ (AUTHOR), Jetton, David¹ (AUTHOR), Jimenez, Jessica¹ (AUTHOR)

Publikováno v: Science. 9/9/2016, Vol. 353 Issue 6304, p1129-1132. 4p. 6 Graphs.

Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning.

Autor: Yu Z; School of Artificial Intelligence, Jilin University, Jilin, 130012, China., Yang Y; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Chen X; Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, USA., Wong KC; Department of Computer Science, City University of Hong Kong, Hong Kong, SAR, 999077, Hong Kong., Zhang Z; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Zhao Y; College of Computer and Control Engineering, Northeast Forestry University, Harbin, 150040, China., Li X; School of Artificial Intelligence, Jilin University, Jilin, 130012, China.; Department of Computer Science, City University of Hong Kong, Hong Kong, SAR, 999077, Hong Kong.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Nov 28, pp. e2410081. Date of Electronic Publication: 2024 Nov 28.

Biomimetic cell culture for cell adhesive propagation for tissue engineering strategies.

Autor: Luo, Qiuchen, Shang, Keyuan, Zhu, Jing, Wu, Zhaoying, Cao, Tiefeng, Ahmed, Abeer Ahmed Qaed, Huang, Chixiang, Xiao, Lin

Publikováno v: Materials Horizons; Nov2023, Vol. 10 Issue 11, p4662-4685, 24p

Advances in Cell-Rich Inks for Biofabricating Living Architectures.

Autor: Almeida-Pinto J; Department of Chemistry, CICECO - Aveiro Institute of Materials, University of Aveiro, Campus Universitário de Santiago, Aveiro, 3810-193, Portugal., Moura BS; Department of Chemistry, CICECO - Aveiro Institute of Materials, University of Aveiro, Campus Universitário de Santiago, Aveiro, 3810-193, Portugal., Gaspar VM; Department of Chemistry, CICECO - Aveiro Institute of Materials, University of Aveiro, Campus Universitário de Santiago, Aveiro, 3810-193, Portugal., Mano JF; Department of Chemistry, CICECO - Aveiro Institute of Materials, University of Aveiro, Campus Universitário de Santiago, Aveiro, 3810-193, Portugal.

Publikováno v: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Jul; Vol. 36 (27), pp. e2313776. Date of Electronic Publication: 2024 May 01.