Zobrazeno 1 - 10
of 133
pro vyhledávání: '"L Fothergill"'
Autor:
Eleri A. Ashworth, Rosanna C. T. Wright, Rebecca K. Shears, Janet K. L. Wong, Akram Hassan, James P. J. Hall, Aras Kadioglu, Joanne L. Fothergill
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Pseudomonas aeruginosa is a major nosocomial pathogen that causes severe disease including sepsis. Carbapenem-resistant P. aeruginosa is recognised by the World Health Organisation as a priority 1 pathogen, with urgent need for new therapeut
Externí odkaz:
https://doaj.org/article/d7674a4d2b9846549863382aa65c4b86
Autor:
H. Blake, S. Carlisle, L. Fothergill, J. Hassard, A. Favier, J. Corner, J. K. Ball, C. Denning
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-26 (2022)
Abstract Background Regular testing for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is an important strategy for controlling virus outbreaks on university campuses during the COVID-19 pandemic but testing participation rates can be l
Externí odkaz:
https://doaj.org/article/d937225310354669bcd270014610c8dc
Autor:
Chowdhury M. Hasan, Sian Pottenger, Angharad E. Green, Adrienne A. Cox, Jack S. White, Trevor Jones, Craig Winstanley, Aras Kadioglu, Megan H. Wright, Daniel R. Neill, Joanne L. Fothergill
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
Pseudomonas aeruginosa undergoes diversification during infection of the cystic fibrosis (CF) lung. Understanding these changes requires model systems that capture the complexity of the CF lung environment. We previously identified loss-of-function m
Externí odkaz:
https://doaj.org/article/22204499f90d4a298bfea430f8163726
Publikováno v:
F1000Research, Vol 11 (2022)
The respiratory tract is a compartmentalised and heterogenous environment. The nasopharynx and sinuses of the upper airways have distinct properties from the lungs and these differences may shape bacterial adaptation and evolution. Upper airway niche
Externí odkaz:
https://doaj.org/article/1f11b0ff41484b5da4e2637771e27865
Autor:
May S. Thu, Thunnicha Ondee, Tanawin Nopsopon, Izzati A. K. Farzana, Joanne L. Fothergill, Nattiya Hirankarn, Barry J. Campbell, Krit Pongpirul
Publikováno v:
Biology, Vol 12, Iss 2, p 280 (2023)
Probiotics may have the potential to protect against breast cancer, partly through systemic immunomodulatory action and active impact upon intestinal microbiota. Given a few clinical studies on their curative role, we conducted a systematic review of
Externí odkaz:
https://doaj.org/article/24433bb34b1848458861d8c229f44b8d
Autor:
Adrian Cazares, Matthew P. Moore, James P. J. Hall, Laura L. Wright, Macauley Grimes, Jean-Guillaume Emond-Rhéault, Pisut Pongchaikul, Pitak Santanirand, Roger C. Levesque, Joanne L. Fothergill, Craig Winstanley
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The emergence of multidrug resistance (MDR) in bacteria represents a global threat to human health. Here, Cazares et al. identify a family of MDR megaplasmids carrying large arrays of antibiotic resistance genes in Pseudomonas strains from various so
Externí odkaz:
https://doaj.org/article/b3e3a6e492364cb59fec9c6d1a7c089f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
P. aeruginosa is classified as a priority one pathogen by the World Health Organisation, and new drugs are urgently needed, due to the emergence of multidrug-resistant (MDR) strains. Antimicrobial-resistant nosocomial pathogens such as P. aeruginosa
Externí odkaz:
https://doaj.org/article/3258fe7fab244c2fa9168b384328561f
Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa
Autor:
Laura Bricio-Moreno, Victoria H. Sheridan, Ian Goodhead, Stuart Armstrong, Janet K.L. Wong, Elaine M. Waters, Joscelyn Sarsby, Stavros Panagiotou, James Dunn, Adrita Chakraborty, Yongliang Fang, Karl E. Griswold, Craig Winstanley, Joanne L. Fothergill, Aras Kadioglu, Daniel R. Neill
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Mutations in gene pmrB are found in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Here, Bricio-Moreno et al. show in a mouse model of respiratory infection that the mutations enhance bacterial adherence to epithelial cells and resist
Externí odkaz:
https://doaj.org/article/dc57b3200e764343a7284314e6587068
Publikováno v:
Journal of Medical Microbiology. 71
Chronic respiratory infection is the primary driver of mortality in individuals with cystic fibrosis (CF). Existing drug screening models utilised in preclinical antimicrobial development are unable to mimic the complex CF respiratory environment. Co
Autor:
Eshwar Mahenthiralingam, Rebecca Weiser, R. Andres Floto, Jane C. Davies, Joanne L. Fothergill
Purpose of ReviewPeople with cystic fibrosis (CF) suffer chronic lung infections with a range of antimicrobial-resistant bacterial pathogens. There is an urgent need for researchers to develop novel anti-infectives to treat these problematic infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5ca62883c56bb22692c114865d7d84