Zobrazeno 1 - 10
of 188
pro vyhledávání: '"L F Prescott"'
Autor:
L F Prescott, John Nimmo
Publikováno v:
Acta Pharmacologica et Toxicologica. 29:288-303
Different preparations of a drug containing the same amount of active chemical in stable form are “chemically equivalent”. Unless they have identical biological activity under clinical conditions, however, they cannot be considered generic equiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c6fba5d0d2f46e1955cd5e187bd178
https://doi.org/10.1111/j.1600-0773.1971.tb03308.x
https://doi.org/10.1111/j.1600-0773.1971.tb03308.x
Autor:
L F Prescott
Publikováno v:
Annals of Emergency Medicine. 45:409-413
Acetaminophen (paracetamol, N-acetyl-p-aminophenol) is an effective, mild analgesic, antipyretic agent and is probably the most widely used of all drugs in the world. It does not share the formidable prostaglandin-dependent toxicity of aspirin and ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f1a2d29fdd22ec61d299d1f4a037b1
https://doi.org/10.1016/j.annemergmed.2004.09.028
https://doi.org/10.1016/j.annemergmed.2004.09.028
Autor:
L F Prescott
Publikováno v:
Drugs. 63:47-51
Paracetamol (acetaminophen) is well established as a leading non-prescription antipyretic analgesic drug. Future developments are likely to include new formulations to achieve rapid absorption for a fast onset of action, and prolonged absorption to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab9bd2c25e15118446171cdc1ea1e409
https://doi.org/10.2165/00003495-200363992-00008
https://doi.org/10.2165/00003495-200363992-00008
Publikováno v:
European Journal of Clinical Pharmacology. 57:853-856
Objective: To evaluate the disposition of paracetamol in renal allograft recipients. Method: Eight fasting renal allograft recipients were given 1 g soluble paracetamol orally. Results: Paracetamol was absorbed rapidly, and the mean plasma half-life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253a3a5283c9894e83098f1aac08ce06
https://doi.org/10.1007/s00228-001-0409-2
https://doi.org/10.1007/s00228-001-0409-2
Autor:
L F Prescott
Publikováno v:
British Journal of Clinical Pharmacology. 49:291-301
It is claimed that chronic alcoholics are at increased risk of paracetamol (acetaminophen) hepatotoxicity not only following overdosage but also with its therapeutic use. Increased susceptibility is supposed to be due to induction of liver microsomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9ceb88b61f501658dcc90140e26761e
https://doi.org/10.1046/j.1365-2125.2000.00167.x
https://doi.org/10.1046/j.1365-2125.2000.00167.x
Autor:
L F Prescott
Publikováno v:
American Journal of Therapeutics. 7:143-148
Paracetamol (acetaminophen) is one of the most widely used of all drugs, with a wealth of experience clearly establishing it as the standard antipyretic and analgesic for mild to moderate pain states. First used clinically by von Mering in 1893, para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc229802723b49c8e0d6b50124c3b85a
https://doi.org/10.1097/00045391-200007020-00011
https://doi.org/10.1097/00045391-200007020-00011
Publikováno v:
Anesthesiology. 87:765-770
Background Opioids delay gastric emptying, which in turn may increase the risk of vomiting and pulmonary aspiration. Naloxone reverses this opiate action on gastric emptying, but it is not known whether this effect in humans is mediated by central or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::047c51cfbd7323ca773263fa0d18aea1
https://doi.org/10.1097/00000542-199710000-00008
https://doi.org/10.1097/00000542-199710000-00008
Publikováno v:
Alimentary Pharmacology and Therapeutics. 11:787-791
Background: The threshold plasma paracetamol concentration at which N-acetylcysteine (NAC) treatment is recommended to treat paracetamol poisoning in a patient with induced liver enzymes (for example, with chronic liver disease or taking anticonvulsa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97e90013838132441aa964891943624
https://doi.org/10.1046/j.1365-2036.1997.00209.x
https://doi.org/10.1046/j.1365-2036.1997.00209.x
Publikováno v:
British Journal of Clinical Pharmacology. 32:495-500
1. The effects of tenoxicam on renal function were studied in 10 patients with chronic renal failure (creatinine clearance 46.7 +/- 11.9 ml min-1 1.73 m-2) and eight healthy volunteers. A parallel treatment control group of eight healthy volunteers r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2875857319510b47cf97dbe2ba1f6e6e
https://doi.org/10.1111/j.1365-2125.1991.tb03937.x
https://doi.org/10.1111/j.1365-2125.1991.tb03937.x
Publikováno v:
Emergency Medicine Journal. 8:165-168
There are few complications associated with intravenous regional anaesthesia but convulsions with loss of consciousness induced by local anaesthetic toxicity may result in pulmonary aspiration. In many hospitals, patients are fasted prior to the proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167f9ad5108ae944402ee5330a67833d
https://doi.org/10.1136/emj.8.3.165
https://doi.org/10.1136/emj.8.3.165