Zobrazeno 1 - 10 of 17 pro vyhledávání: '"L F, Reichardt"'
1
Development and evolution of inner ear sensory epithelia and their innervation
Autor: B, Fritzsch, K W, Beisel, K, Jones, I, Fariñas, A, Maklad, J, Lee, L F, Reichardt
Publikováno v: Journal of neurobiology. 53(2)
The development and evolution of the inner ear sensory patches and their innervation is reviewed. Recent molecular developmental data suggest that development of these sensory patches is a developmental recapitulation of the evolutionary history. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6485b70c6ebf5bb305c060c23e965406
https://pubmed.ncbi.nlm.nih.gov/12382272
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2
Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB
Autor: B, Xu, K, Zang, N L, Ruff, Y A, Zhang, S K, McConnell, M P, Stryker, L F, Reichardt
Publikováno v: Neuron. 26(1)
To examine functions of TrkB in the adult CNS, TrkB has been removed from neurons expressing CaMKII, primarily pyramidal neurons, using Cre-mediated recombination. A floxed trkB allele was designed so that neurons lacking TrkB express tau-beta-galact
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::41a33209b34032fd8ea3f0dec71ab41c
https://pubmed.ncbi.nlm.nih.gov/10798407
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3
Role of neurotrophin receptor TrkB in the maturation of rod photoreceptors and establishment of synaptic transmission to the inner retina
Autor: B, Rohrer, J I, Korenbrot, M M, LaVail, L F, Reichardt, B, Xu
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 19(20)
Brain-derived neurotrophic factor (BDNF) acts through TrkB, a receptor with kinase activity, and mitigates light-induced apoptosis in adult mouse rod photoreceptors. To determine whether TrkB signaling is necessary for rod development and function, w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::276b6c3f25c1bfc4bb36357a4d26a11e
https://pubmed.ncbi.nlm.nih.gov/10516311
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5
Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo
Autor: I, Fariñas, G A, Wilkinson, C, Backus, L F, Reichardt, A, Patapoutian
Publikováno v: Neuron. 21(2)
Spinal sensory ganglia have been shown to contain neuronal subpopulations with different functions and neurotrophin dependencies. Neurotrophins act, in large part, through Trk receptor tyrosine kinases: nerve growth factor (NGF) via TrkA, brain-deriv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a75e63d760415f832c5b2c3c139deb5c
https://pubmed.ncbi.nlm.nih.gov/9728914
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6
Neurotrophin-3 promotes the differentiation of muscle spindle afferents in the absence of peripheral targets
Autor: R A, Oakley, F B, Lefcort, D O, Clary, L F, Reichardt, D, Prevette, R W, Oppenheim, E, Frank
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 17(11)
The neurons of the dorsal root ganglia (DRG) that supply muscle spindles require target-derived factors for survival. One necessary factor for these neurons is neurotrophin-3 (NT3). To determine whether NT3 can promote the survival of these neurons i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa984b4b7ef70fd217ef3f8cd2cd8961
https://pubmed.ncbi.nlm.nih.gov/9151743
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7
Retrograde transport of neurotrophins from the eye to the brain in chick embryos: roles of the p75NTR and trkB receptors
Autor: C S, von Bartheld, R, Williams, F, Lefcort, D O, Clary, L F, Reichardt, M, Bothwell
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 16(9)
The receptors involved in retrograde transport of neurotrophins from the retina to the isthmo-optic nucleus (ION) of chick embryos were characterized using antibodies to the p75 neurotrophin receptor and trkB receptors. Survival of neurons in the ION
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::27b9a7cc17e674da2e7f00022ac30968
https://pubmed.ncbi.nlm.nih.gov/8622129
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8
TrkA expression in the CNS: evidence for the existence of several novel NGF-responsive CNS neurons
Autor: D M, Holtzman, J, Kilbridge, Y, Li, E T, Cunningham, N J, Lenn, D O, Clary, L F, Reichardt, W C, Mobley
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 15(2)
NGF acts as a neurotrophic factor by binding and activating its receptor on certain neuronal populations in the CNS and PNS. TrkA is a receptor for NGF. Recent findings in vitro indicate that this NGF-activated receptor tyrosine kinase transduces the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::556f7f1b1e57553ba54fe4cdcb73c126
https://pubmed.ncbi.nlm.nih.gov/7869118
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10
A neuronal cell line (PC12) expresses two beta 1-class integrins-alpha 1 beta 1 and alpha 3 beta 1-that recognize different neurite outgrowth-promoting domains in laminin
Autor: K J, Tomaselli, D E, Hall, L A, Flier, K R, Gehlsen, D C, Turner, S, Carbonetto, L F, Reichardt
Publikováno v: Neuron. 5(5)
Integrins mediate neuronal process outgrowth on components of the ECM. Integrin alpha subunit-specific antibodies have been used to examine the roles of individual beta 1 integrins in attachment and neurite outgrowth by the neuronal cell line, PC12,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::abfe94d97083dd14024690d9654bb764
https://pubmed.ncbi.nlm.nih.gov/2223092
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