Zobrazeno 1 - 10
of 330
pro vyhledávání: '"L Elliot Hong"'
Publikováno v:
PLoS Biology, Vol 18, Iss 10, p e3000883 (2020)
Humans are remarkably skilled at listening to one speaker out of an acoustic mixture of several speech sources. Two speakers are easily segregated, even without binaural cues, but the neural mechanisms underlying this ability are not well understood.
Externí odkaz:
https://doaj.org/article/c1f2f771b5cd4a0e8b19a25747d4ebc8
Autor:
Veronica eMerelo, Dante eDurand, Adam R Lescallette, Kent E Vrana, L Elliot Hong, Mohammad Ali Faghihi, Alfredo eBellon
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2015)
Several lines of evidence indicate that schizophrenia has a strong genetic component. But the exact nature and functional role of this genetic component in the pathophysiology of this mental illness remains a mystery. Long non-coding RNAs (lncRNAs) a
Externí odkaz:
https://doaj.org/article/a7448b974a7d4b168cd4bce08bbb94fc
Autor:
Yi Yin, Chen Lin, Lijing Wei, Jinghui Tong, Junchao Huang, Baopeng Tian, Shuping Tan, Zhiren Wang, Fude Yang, Yongsheng Tong, Song Chen, L. Elliot Hong, Yunlong Tan
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Clozapine is an off-label drug used in most countries to prevent suicide in individuals with schizophrenia. However, few studies have reported real-world prescription practices. This study aimed to explore the association between
Externí odkaz:
https://doaj.org/article/7586f9b9413441a69b8cad3a8f1ba75d
Autor:
Xiaoming Du, Fow-Sen Choa, Joshua Chiappelli, Heather Bruce, Mark Kvarta, Ann Summerfelt, Yizhou Ma, William T. Regenold, Kevin Walton, George F. Wittenberg, Stephanie Hare, Si Gao, Andrew van der Vaart, Zhiwei Zhao, Shuo Chen, Peter Kochunov, L. Elliot Hong
Publikováno v:
Brain Stimulation, Vol 17, Iss 2, Pp 324-332 (2024)
The smoking rate is high in patients with schizophrenia. Brain stimulation targeting conventional brain circuits associated with nicotine addiction has also yielded mixed results. We aimed to identify alternative circuitries associated with nicotine
Externí odkaz:
https://doaj.org/article/19a62d0c0d86446e9e5578dccda7a876
Publikováno v:
Sensors, Vol 24, Iss 23, p 7742 (2024)
Brain connectivity represents the functional organization of the brain, which is an important indicator for evaluating neuropsychiatric disorders and treatment effects. Schizophrenia is associated with impaired functional connectivity but characteriz
Externí odkaz:
https://doaj.org/article/c1e1bb2612de44da9102f5861d8dab4c
Autor:
Yanli Li, Leilei Wang, Junchao Huang, Ping Zhang, Yanfang Zhou, Jinghui Tong, Wenjin Chen, Mengzhuang Gou, Baopeng Tian, Wei Li, Xingguang Luo, Li Tian, L. Elliot Hong, Chiang-Shan R. Li, Yunlong Tan
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundMany studies showed disrupted tryptophan metabolism in patients with affective disorders. The aims of this study were to explore the differences in the metabolites of tryptophan pathway (TP) and the relationships between TP metabolites and
Externí odkaz:
https://doaj.org/article/172995bb0031487ca4805e06da8ea12b
Autor:
Yizhou Ma, Joshua Chiappelli, Mark D. Kvarta, Heather Bruce, Andrew van der Vaart, Eric L. Goldwaser, Xiaoming Du, Hemalatha Sampath, Samantha Lightner, Jane Endres, Akram Yusuf, Alexa Yuen, Samantha Narvaez, Danny Campos-Saravia, Peter Kochunov, L. Elliot Hong
Publikováno v:
Schizophrenia, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract We evaluated two models to link stressful life events (SLEs) with the psychopathology of schizophrenia spectrum disorders (SSD). We separated SLEs into independent (iSLEs, unlikely influenced by one’s behavior) and dependent (dSLEs, likely
Externí odkaz:
https://doaj.org/article/73e77d3ee4264ab1ac7459673a99692d
Autor:
Ling Yan, Yanli Li, Fengmei Fan, Mengzhuang Gou, Fangling Xuan, Wei Feng, Keerthana Chithanathan, Wei Li, Junchao Huang, Hongna Li, Wenjin Chen, Baopeng Tian, Zhiren Wang, Shuping Tan, Alexander Zharkovsky, L. Elliot Hong, Yunlong Tan, Li Tian
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Microglia are known to regulate stress and anxiety in both humans and animal models. Psychosocial stress is the most common risk factor for the development of schizophrenia. However, how microglia/brain macrophages contribute to s
Externí odkaz:
https://doaj.org/article/3688731ab7f54d3e93ad89bc88e2f32a
Autor:
Cheng Tian, Zhenyao Ye, Rozalina G. McCoy, Yezhi Pan, Chuan Bi, Si Gao, Yizhou Ma, Mo Chen, Jiaao Yu, Tong Lu, L. Elliot Hong, Peter Kochunov, Tianzhou Ma, Shuo Chen, Song Liu
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
BackgroundPoor glycemic control with elevated levels of hemoglobin A1c (HbA1c) is associated with increased risk of cognitive impairment, with potentially varying effects between sexes. However, the causal impact of poor glycemic control on white mat
Externí odkaz:
https://doaj.org/article/cc547b1548e64017bbec797e74fac68b
Autor:
Xiaoming Du, Stephanie Hare, Ann Summerfelt, Bhim M. Adhikari, Laura Garcia, Wyatt Marshall, Peng Zan, Mark Kvarta, Eric Goldwaser, Heather Bruce, Si Gao, Hemalatha Sampath, Peter Kochunov, Jonathan Z. Simon, L. Elliot Hong
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Aberrant gamma frequency neural oscillations in schizophrenia have been well demonstrated using auditory steady-state responses (ASSR). However, the neural circuits underlying 40 Hz ASSR deficits in schizophrenia remain poorly understood. Si
Externí odkaz:
https://doaj.org/article/5af5ae085cfe4fa19d64a2635f262793