Zobrazeno 1 - 10
of 58
pro vyhledávání: '"L E. Mather"'
Publikováno v:
European Respiratory Journal. 10:2270-2274
Systemic opiates may relieve dyspnoea and improve exercise tolerance in patients with chronic obstructive pulmonary disease (COPD). Small doses of inhaled opiates may have similar effects; however, recent studies have shown no benefit. We studied hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90efa7abab2e71dbd05bab5721bfa76f
https://doi.org/10.1183/09031936.97.10102270
https://doi.org/10.1183/09031936.97.10102270
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 688:79-85
A method was devised to determine fentanyl plasma concentrations by GC-MS using selected-ion monitoring (SIM) with sufentanil as internal standard. This was compared with a commonly used commercial radioimmunoassay (RIA). Sample preparation for GC-MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3259b8fc3200207c3e8be5428b98d160
https://doi.org/10.1016/s0378-4347(97)88058-9
https://doi.org/10.1016/s0378-4347(97)88058-9
Autor:
L E, Mather
Publikováno v:
Minerva anestesiologica. 71(9)
Isomers are molecules that have the same number of the same kind of atoms arranged in different ways. There are two major categories of isomers: constitutional (or structural) isomers and stereoisomers. Stereoisomers have identical sets of atoms that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f7dbf75b18ee255fdd9f6bc1e305d28
https://pubmed.ncbi.nlm.nih.gov/16166909
https://pubmed.ncbi.nlm.nih.gov/16166909
Publikováno v:
Life sciences. 69(4)
In humans, hydromorphone (HMOR) is metabolised principally by conjugation with glucuronic acid to form hydromorphone-3-glucuronide (H3G), a close structural analogue of morphine-3-glucuronide (M3G), the major metabolite of morphine. In a previous stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57de4c855c00cf668f5f7363ac42f05e
https://pubmed.ncbi.nlm.nih.gov/11459432
https://pubmed.ncbi.nlm.nih.gov/11459432
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 297(1)
This study investigated possible sex-related differences in levels of antinociception and the rate of development of tolerance to the antinociceptive effects following prolonged (48 h) intravenous (i.v.) morphine administration in the rat. Groups of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b38ba930cbeb07c61d4ab133a641a800
https://pubmed.ncbi.nlm.nih.gov/11259573
https://pubmed.ncbi.nlm.nih.gov/11259573
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(2)
The myocardial kinetics of meperidine and the relationship between these kinetics and the effect of meperidine on myocardial contractility (maximum positive rate of change of left ventricular pressure) were examined by analysis of previously publishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e64dc422a1f314f46fedf618d8a6fda0
https://pubmed.ncbi.nlm.nih.gov/10411580
https://pubmed.ncbi.nlm.nih.gov/10411580
Publikováno v:
Anesthesia and analgesia. 87(5)
N-methyl-D-aspartate (NMDA) antagonists combined with opioids are thought to be effective in the control of pain states. We evaluated morphine use and analgesia in 37 patients postlaparotomy. Patients received 60 mg of oral dextromethorphan or placeb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a00129b615fa6a8444081f1f27bda36
https://pubmed.ncbi.nlm.nih.gov/9806696
https://pubmed.ncbi.nlm.nih.gov/9806696
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(2)
The influence of experimentally induced renal failure on the disposition of morphine, morphine-3-glucuronide (M3G) and morphine-6-glucuronide (M6G) was examined in seven sheep infused intravenously with morphine for 6 hr. Between 5 and 6 hr, blood wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3536777586cee282d6480805e1400c9b
https://pubmed.ncbi.nlm.nih.gov/9262341
https://pubmed.ncbi.nlm.nih.gov/9262341
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 279(1)
Thiopental is used as a racemate (rac-thiopental). Enantiomeric pharmacokinetic differences could therefore influence the onset and duration of anesthesia of rac-thiopental. We studied the systemic and cerebral kinetics of R(+)- and S(-)-thiopental i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58ac40a69d4b7fbd9c0aa24e53fb55be
https://pubmed.ncbi.nlm.nih.gov/8859006
https://pubmed.ncbi.nlm.nih.gov/8859006
Autor:
L E, Mather
Publikováno v:
Clinical and experimental pharmacologyphysiology. 22(11)
1. Opioids, in one form or another, have been used for their pain-relieving properties from prehistoric times: they are still the first line medication for the treatment of severe nociceptive pain and are likely to remain so for the foreseeable futur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::355411dceeb04af3fa83c1964d064d3e
https://pubmed.ncbi.nlm.nih.gov/8593739
https://pubmed.ncbi.nlm.nih.gov/8593739