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pro vyhledávání: '"L E Donnelly"'
Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in COPD
Autor:
R. Singh, K. B. R. Belchamber, P. S. Fenwick, K. Chana, G. Donaldson, J. A. Wedzicha, P. J. Barnes, L. E. Donnelly, COPDMAP consortium
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Lower airway bacterial colonisation (LABC) in COPD patients is associated with increased exacerbation frequency and faster lung function decline. Defective macrophage phagocytosis in COPD drives inflammation, but how defective mac
Externí odkaz:
https://doaj.org/article/100d24a891c14ece8c0df68509288966
Publikováno v:
03.02 - Airway cell biology and immunopathology.
Autor:
L E, Donnelly
Publikováno v:
Methods in molecular medicine. 56
The cells lining the airway consist of epithelial cells, of which there are several types including columnar cells, basal cells, and secretory/goblet cells. It is these cells which are the first lines of defense against airborne inflammatory agents.