Zobrazeno 1 - 9 of 9 pro vyhledávání: '"L E, Scudder"'
1
Structure and function of murine alphaIIbbeta3 (GPIIb/IIIa): studies using monoclonal antibodies and beta3-null mice
Autor: S S, Smyth, D A, Tsakiris, L E, Scudder, B S, Coller
Publikováno v: Thrombosis and haemostasis. 84(6)
The alphaIIbeta3 receptor (GPIIb/IIIa) is the only platelet-specific integrin receptor and the most abundant adhesion/aggregation receptor on the surface of human platelets. Since mice are increasingly being used as models of human disease, we analyz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6b0c3dfcca8817a5d486ef8ba6742854
https://pubmed.ncbi.nlm.nih.gov/11154120
Zobrazit plný text záznamu
2
A Cys374Tyr homozygous mutation of platelet glycoprotein IIIa (beta 3) in a Chinese patient with Glanzmann's thrombasthenia
Autor: C M, Grimaldi, F, Chen, L E, Scudder, B S, Coller, D L, French
Publikováno v: Blood. 88(5)
A 20-year-old woman from a consanguineous family in the Hunan Province of the People's Republic of China was diagnosed as having Glanzmann's thrombasthenia based on (1) nearly a lifelong history of epistaxis, gum bleeding, petechiae, and purpura; (2)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7034343d3d6104fd54a243fcc037fb86
https://pubmed.ncbi.nlm.nih.gov/8781422
Zobrazit plný text záznamu
3
Substituting isoserine for serine in the thrombin receptor activation peptide SFLLRN confers resistance to aminopeptidase M-induced cleavage and inactivation
Autor: B S, Coller, K T, Springer, L E, Scudder, J L, Kutok, M, Ceruso, G D, Prestwich
Publikováno v: The Journal of biological chemistry. 268(28)
Peptides containing sequences derived from the new NH2 terminus of the seven-transmembrane domain thrombin receptor after thrombin cleavage can activate platelets directly. We recently demonstrated that such peptides are readily cleaved and inactivat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::821abf827d795b179facb8563b3f2d9a
https://pubmed.ncbi.nlm.nih.gov/8104935
Zobrazit plný text záznamu
5
Platelet fibrinogen and vitronectin in Glanzmann thrombasthenia: evidence consistent with specific roles for glycoprotein IIb/IIIA and alpha v beta 3 integrins in platelet protein trafficking
Autor: B S, Coller, U, Seligsohn, S M, West, L E, Scudder, K J, Norton
Publikováno v: Blood. 78(10)
To assess the individual contributions of the platelet glycoprotein (GP) IIb/IIIa receptor and the alpha v beta 3 vitronectin receptor to platelet levels of fibrinogen and vitronectin, we analyzed the platelets from two groups of Glanzmann thrombasth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5f2f2f8574fdf70f1893f4beec28106e
https://pubmed.ncbi.nlm.nih.gov/1596579
Zobrazit plný text záznamu
6
Inhibition of dog platelet function by in vivo infusion of F(ab')2 fragments of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor
Autor: B S, Coller, L E, Scudder
Publikováno v: Blood. 66:1456-1459
To assess the potential of monoclonal antibodies that inhibit platelet function in vitro as in vivo therapeutic agents, F(ab')2 fragments (0.17 to 0.81 mg/kg) of a murine monoclonal antibody (7E3) that binds to platelet glycoproteins IIb and/or IIIa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a353a24e1d217b9ee486009b83379ea
https://doi.org/10.1182/blood.v66.6.1456.bloodjournal6661456
Zobrazit plný text záznamu
7
Monoclonal antibody against the platelet glycoprotein (GP) IIb/IIIa receptor prevents coronary artery reocclusion after reperfusion with recombinant tissue-type plasminogen activator in dogs
Autor: Robert C. Leinbach, D. Collen, L E Scudder, J L Guerrero, Michito Kanke, Tsunehiro Yasuda, John T. Fallon, M J Ross, D Shealy, Herman K. Gold
Publikováno v: Journal of Clinical Investigation. 81:1284-1291
Localized thrombosis was produced in the left anterior descending (LAD) coronary artery of open chest dogs by constricting a segment so as to produce greater than 90% stenosis (reducing blood flow to 40 +/- 10% of baseline), and placing a thrombus in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df34959465e24074425e44f753ef8c9
https://doi.org/10.1172/jci113446
Zobrazit plný text záznamu
8
Antithrombotic effect of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor in an experimental animal model
Autor: B S, Coller, J D, Folts, L E, Scudder, S R, Smith
Publikováno v: Blood. 68:783-786
A murine monoclonal antibody directed at the platelet glycoprotein IIb/IIIa complex, which blocks platelet aggregation ex vivo, was tested for its antithrombotic effects in an established animal model of acute platelet thrombus formation in partially
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fc1ce9365fdbfe7c2ddc686dc8b81d
https://doi.org/10.1182/blood.v68.3.783.bloodjournal683783
Zobrazit plný text záznamu
9
Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor
Autor: B S, Coller, E I, Peerschke, L E, Scudder, C A, Sullivan
Publikováno v: Blood. 61(1)
A murine monoclonal antibody directed at or near a platelet membrane receptor for the von Willebrand factor was produced by the hybridoma technique. Purified F(ab')2 fragments and/or intact antibody completely blocked the agglutination of platelets i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e08b6b91c67f7b3a5f6c7ce885357f0
https://pubmed.ncbi.nlm.nih.gov/6336654
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje