Zobrazeno 1 - 10 of 233 pro vyhledávání: '"L E, SUTTON"'
1
Metallo-β-lactamase: Inhibitors and reporter substrates
Autor: L. E. Sutton, Walter L Fast
Publikováno v: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1834:1648-1659
Metallo-β-lactamases represent an emerging clinical threat due to their ability to render ineffective an entire class of antibiotics. Accordingly, this family of enzymes has been suggested as an attractive target for drug design. Progress toward dev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da1d974bfb9337ac292d35b4e85ba01
https://doi.org/10.1016/j.bbapap.2013.04.024
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2
Targeting metallo-carbapenemases via modulation of electronic properties of cephalosporins
Autor: Hao Yang, Michael W. Crowder, L. E. Sutton, Sophia Yu, Heather Young
Publikováno v: The Biochemical journal. 464(2)
The global proliferation of metallo-carbapenemase-producing Enterobacteriaceae has created an unmet need for inhibitors of these enzymes. The rational design of metallo-carbapenemase inhibitors requires detailed knowledge of their catalytic mechanism
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c759ac4f8f41dfae3d1d138d084943
https://pubmed.ncbi.nlm.nih.gov/25220027
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3
A chromogenic cephalosporin for β-lactamase inhibitor screening assays
Autor: Jacob Schesser, L. E. Sutton, Katherine Corbella, Amy Vosbeek, Sophia Yu, Jonathan Severson
Publikováno v: Analytical biochemistry. 428(2)
Production of β-lactamases is the primary mechanism of antibiotic resistance employed by gram-negative pathogens. Chromogenic β-lactams are important reagents for detection and assay of β-lactamases, but limited commercial availability and exorbit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908d9223a6bc4a7c36a44a3be9acd70c
https://pubmed.ncbi.nlm.nih.gov/22709853
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6
Elektronická kniha
Molecular Structure by Diffraction Methods : Volume 1
Autor: G A Sim, L E Sutton
Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supp
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