Zobrazeno 1 - 2
of 2
pro vyhledávání: '"L E, Randle"'
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0275788 (2022)
Precision cut liver slices represent an encouraging ex vivo method to understand the pathogenesis of liver disease alongside drug induced liver injury. Despite being more physiologically relevant compared to in vitro models, precision cut liver slice
Externí odkaz:
https://doaj.org/article/6a64cdb531b54d569ef6025762b8d4ef
Publikováno v:
British journal of pharmacology. 153(4)
Paracetamol, a major cause of acute liver failure (ALF) represents a significant clinical problem. Adrenoceptor stimulation or antagonism can modulate chemical-induced hepatotoxicity. We investigated the role of endogenous catecholamines and alpha(1)