Zobrazeno 1 - 10
of 46
pro vyhledávání: '"L Drell"'
Autor:
Corinna Weidt, Bernd Niggemann, Benjamin Kasenda, Theodore Drell, Kurt Zanker, Thomas Dittmar, Theodore L. Drell, Kurt S. Zanker
Publikováno v:
Current Stem Cell Research & Therapy. 2:89-103
Migration is an innate and fundamental cellular function that enables hematopoietic stem cells (HSCs) and endothelial progenitors (EPCs) to leave the bone marrow, relocate to distant tissue, and to return to the bone marrow. An increasing number of s
Autor:
Kerstin Lang, Bernd Niggemann, Theodore L. Drell, Frank Entschladen, Kai Masur, Daniel Palm, Kurt S. Zaenker
Publikováno v:
International Journal of Cancer. 118:2744-2749
The development of metastases is a decisive step in the course of a cancer disease. The detection of metastases in cancer patients is correlated with a poor prognosis, and over 90% of all deaths from cancer are not due to the primary tumor, which oft
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 1:69-80
A leading cause of death, cancer remains the bane of modern society and one of the most challenging research fields. Cancer is initially a localized disease that can be often treated well at a very early stage. However the vast majority of cancer dea
Autor:
Daniel Palm, Frank Entschladen, Philipp Bastian, Kerstin Lang, Kurt S. Zaenker, Bernd Niggemann, Theodore L. Drell, Kai Masur
Publikováno v:
Experimental Cell Research. 307:418-426
The autonomous migration of specialized cells is an essential characteristic in both physiological and pathological functions in the adult human organism. Leukocytes, fibroblasts, and stem cells, but also tumor cells, are thus the subject of intense
Publikováno v:
Current Pharmaceutical Design. 11:403-411
The migration of tumor cells is a prerequisite for tumor cell invasion and metastasis development, which accounts for over 90% of cancer mortality. Therefore a major focus of current tumor biological research is the study of those factors that regula
Autor:
Theodore L. Drell, Frank Entschladen, Philipp Bastian, Daniel Palm, Stefanie Potthoff, Kerstin Lang, Kurt S. Zänker
Publikováno v:
Signal Transduction. 5:9-18
Migration is an essential function of cells; it is involved in reproduction and embryogenesis, as well as in the cellular, immunological defense of an organism against pathogens. On the pathological site, migration of tumor cells represents a pernici
Autor:
Bernd Niggemann, Theodore L. Drell, Kurt S. Zaenker, Kerstin Lang, Frank Entschladen, Corinna Weidt, Jan Joseph
Publikováno v:
Experimental Cell Research. 298:178-187
Although great strides have recently been made in elucidating the factors initiating tumor cell migration and the relevant cellular pathways involved, the constituent components of migratory dynamics for individual tumor cell motion have still not be
Autor:
S B Tunick, A J Salerian, W Byrd, L Drell, W E Deibler, S P Geyer, S Fleisher, M Wax, J A Mirczak, B J Vittone, N Mirmirani
Publikováno v:
Journal of Sex & Marital Therapy. 26:133-140
Ninety-two outpatients (31 women, 61 men) who were treated with oral sildenafil for psychotropic-induced sexual dysfunction (PISD) completed ratings of their sexual functioning pre- and posttreatment. Both women and men reported significant improveme
Publikováno v:
Current pharmaceutical design. 18(23)
Cancer remains one of the leading causes of death in the Western world. Despite bold advances in therapeutic oncology, new drug development is infamously ineffective due to the lack of predictive in vitro models. Most patients that suffer from cancer
Publikováno v:
Current pharmaceutical design. 13(33)
Tumor cells are not only susceptible to signals from the environment, but they likewise release signal substances. It is well known that tumor cells secrete angiogenic factors - most prominently the vascular endothelial growth factor - which initiate