Zobrazeno 1 - 10
of 710
pro vyhledávání: '"L Dent"'
Autor:
Josephina A. N. Meester, Anne Hebert, Maaike Bastiaansen, Laura Rabaut, Jarl Bastianen, Nele Boeckx, Kathryn Ashcroft, Paldeep S. Atwal, Antoine Benichou, Clarisse Billon, Jan D. Blankensteijn, Paul Brennan, Stephanie A. Bucks, Ian M. Campbell, Solène Conrad, Stephanie L. Curtis, Majed Dasouki, Carolyn L. Dent, James Eden, Himanshu Goel, Verity Hartill, Arjan C. Houweling, Bertrand Isidor, Nicola Jackson, Pieter Koopman, Anita Korpioja, Minna Kraatari-Tiri, Liina Kuulavainen, Kelvin Lee, Karen J. Low, Alan C. Lu, Morgan L. McManus, Stephen P. Oakley, James Oliver, Nicole M. Organ, Eline Overwater, Nicole Revencu, Alison H. Trainer, Bhavya Trivedi, Claire L. S. Turner, Rebecca Whittington, Andreas Zankl, Dominica Zentner, Lut Van Laer, Aline Verstraeten, Bart L. Loeys
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Pathogenic loss-of-function variants in BGN, an X-linked gene encoding biglycan, are associated with Meester-Loeys syndrome (MRLS), a thoracic aortic aneurysm/dissection syndrome. Since the initial publication of five probands in 2017, we ha
Externí odkaz:
https://doaj.org/article/59c29ea90e714804ab5f4038f2662271
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundProblematic cannabis use is highly prevalent among people with mood disorders. This underscores the need to understand the effects of cannabis and cannabinoids in this population, especially considering legalization of recreational cannabis
Externí odkaz:
https://doaj.org/article/24def20bb19e4224bfe77958eeb78e12
Autor:
Elizabeth P Scherer, Erika Paola Brigmon, Susannah Nicholson, Angelo Ciaraglia, Deborah L Schwartz, Daniel L Dent
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 9, Iss 1 (2024)
The practice of surgical critical care (SCC) has traditionally necessitated additional in-house, extended night and weekend clinical commitments, which can be viewed as less desirable for many surgeons. Therefore, the authors have observed that some
Externí odkaz:
https://doaj.org/article/6da0d4a853df428d8e5eacffb9a842d7
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionObesity during childhood is a serious and growing chronic disease with consequences for lifelong health. In an effort to advance research into the preclinical indicators of pediatric obesity, we examined longitudinal assessments of uric a
Externí odkaz:
https://doaj.org/article/0d93d44c5fff429da5ecf3e47699668d
Autor:
Alexis Lin, Gelonia L. Dent, Suzy Davies, Zarena M. Dominguez, Leigh-Anne Cioffredi, Gabrielle L. McLemore, Jessie R. Maxwell
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Cannabinoid use in all populations is increasing as legalization across the United States continues. Concerningly, there is a lack of caution provided by medical providers to pregnant individuals as to the impact the use of cannabinoids could have on
Externí odkaz:
https://doaj.org/article/cf115c21a82c456bb673a73e29395e44
Autor:
Alexis S Dadelahi, Mostafa F N Abushahba, Bárbara Ponzilacqua-Silva, Catherine A Chambers, Charles R Moley, Carolyn A Lacey, Alexander L Dent, Jerod A Skyberg
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011672 (2023)
Brucellosis, caused by facultative, intracellular Brucella spp., often results in chronic and/or lifelong infection. Therefore, Brucella must employ mechanisms to subvert adaptive immunity to cause chronic infection. B lymphocytes enhance susceptibil
Externí odkaz:
https://doaj.org/article/44ea05f424284566a1173f4ca08e2b85
Autor:
Fang Ke, Zachary L Benet, Mitra P Maz, Jianhua Liu, Alexander L Dent, Joanne Michelle Kahlenberg, Irina L Grigorova
Publikováno v:
eLife, Vol 12 (2023)
Follicular regulatory T cells (Tfr) restrict development of autoantibodies and autoimmunity while supporting high-affinity foreign antigen-specific humoral response. However, whether Tfr can directly repress germinal center (GC) B cells that acquire
Externí odkaz:
https://doaj.org/article/859bb3259706499e8d6e931c50a4ed50
Autor:
D. Alejandro Canaria, Maia G. Clare, Bingyu Yan, Charlotte B. Campbell, Zachariah A. Ismaio, Nicole L. Anderson, Sungtae Park, Alexander L. Dent, Majid Kazemian, Matthew R. Olson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IL-9-producing CD4+ T helper cells, termed Th9 cells, differentiate from naïve precursor cells in response to a combination of cytokine and cell surface receptor signals that are elevated in inflamed tissues. After differentiation, Th9 cells accumul
Externí odkaz:
https://doaj.org/article/f8a357bbff2a4fd8819701a96855a258
Autor:
Mustafa Tamim Alam Khan, Ronit Patnaik, Allison N. Laffoon, Lucijana Krokar, Spencer R. Ince, Estefania Hurtado, Mio Kitano, Danielle M. Fritze, Daniel L. Dent
Publikováno v:
Journal of Surgical Research. 288:43-50
Autor:
Yuhong Chen, Mei Yu, Yongwei Zheng, Guoping Fu, Gang Xin, Wen Zhu, Lan Luo, Robert Burns, Quan-Zhen Li, Alexander L. Dent, Nan Zhu, Weiguo Cui, Laurent Malherbe, Renren Wen, Demin Wang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
B cell response and antibody production are generally facilitated by CD4+ follicular helper (Tfh) cells. Here the authors identify a subset of CXCR5+PD1+CD8+ Tfh cells that is normally suppressed by STAT5 signaling, so that STAT5 deficiency in mice i
Externí odkaz:
https://doaj.org/article/3b58b83ee76b4ab8925812d290639692