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STAT3 Inhibits Autocrine IFN Signaling in Type I Conventional Dendritic Cells

Autor: Taylor T. Chrisikos, Yifan Zhou, Laura M. Kahn, Bhakti Patel, Nina L. Denne, Athena Brooks, Li Shen, Jing Wang, Stephanie S. Watowich

Publikováno v: The Journal of Immunology. 209:1286-1299

Type I conventional dendritic cells (cDC1s) are an essential Ag-presenting population required for generating adaptive immunity against intracellular pathogens and tumors. While the transcriptional control of cDC1 development is well understood, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f5eb3f3848ba750f27c9ba736167b7
https://doi.org/10.4049/jimmunol.2101104

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Ralstonia solanacearum Effectors Localize to Diverse Organelles in Solanum Hosts

Autor: Raka M. Mitra, Anjali S. Iyer-Pascuzzi, Oleksandr Kyrysyuk, Rachel R Hiles, Nina L Denne

Publikováno v: Phytopathology®. 111:2213-2226

Phytopathogenic bacteria secrete type III effector (T3E) proteins directly into host plant cells. T3Es can interact with plant proteins and frequently manipulate plant host physiological or developmental processes. The proper subcellular localization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e105cb360d472890352e5c3c0380985c
https://doi.org/10.1094/phyto-10-20-0483-r

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Akademický článek

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Contemporary epidemiology of infective endocarditis in patients with congenital heart disease: A UK prospective study

Autor: L Denne, Thomas J. Cahill, A Frigiola, RC Franklin, E Orchard, P D Jewell, Bernard Prendergast

Publikováno v: American heart journal. 215

Infective endocarditis is a life-threatening complication of congenital heart disease (CHD), but there are few studies concerning the contemporary risk profile, preceding invasive procedures and outcomes in this patient population. The aim of this st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1f9fe1f71bfa0e8eddff6346165073
https://pubmed.ncbi.nlm.nih.gov/31299559

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P2470Contemporary epidemiology of infective endocarditis in patients with congenital heart disease: outcomes from a national prospective study

Autor: Bernard Prendergast, RC Franklin, L Denne, Thomas J. Cahill, D Cunningham, P D Jewell, Alessandra Frigiola

Publikováno v: European Heart Journal. 39

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5b8858c7b66ae5c201cf28734ef9d34
https://doi.org/10.1093/eurheartj/ehy565.p2470

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Abstract P2-09-05: The potent anti-androgen enzalutamide demonstrates broad anti-tumour activity across all androgen receptor-positive triple-negative breast cancer subtypes

Autor: V. Haley, Karen O’Leary, F. Cavicchioli, Peter Schmid, E Komulainen, A Shia, L Denne, Catherine Lenihan

Publikováno v: Cancer Research. 73:P2-09

Background: Up to 30% of triple-negative breast cancers (TNBC) show expression of the androgen receptor (AR) and may therefore be candidates for AR-targeted therapy. Molecular profiling of TNBC has identified the luminal AR (LAR) subset, which shares

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::613c4e5070f21dbf3cf2a90c2cf725f7
https://doi.org/10.1158/0008-5472.sabcs13-p2-09-05

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Acellular cadaveric dermis (Alloderm) for ventricular coverage after a gunshot wound

Autor: Carlos R. Medina, Mark J. Seamon, Thomas A. Santora, Jennifer L Denne, Amy J. Goldberg, Mahender Macha, Abhijit Pathak, Paola Pieri, Tolupe Akinyemi, Kevin M. Bradley

Publikováno v: Injury Extra. 39:123-126

Firearm injuries of the left ventricle are often fatal. Successful outcome depends on the rapid identification of all injuries and development of a well-organised, effective treatment plan. We report the case of a patient that sustained multiple thor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c11795e6ee6cfe7b5f50ccc68cb8b73
https://doi.org/10.1016/j.injury.2007.10.001

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