Zobrazeno 1 - 10
of 124
pro vyhledávání: '"L Delahaye"'
Autor:
Sara B. Cohen, Courtney R. Plumlee, Lindsay Engels, Dat Mai, Tara A. Murray, Ana N. Jahn, Bridget Alexander, Jared L. Delahaye, Lauren M. Cross, Karolina Maciag, Sam Schrader, Kaitlin Durga, Elizabeth S. Gold, Alan Aderem, Michael Y. Gerner, Benjamin H. Gern, Alan H. Diercks, Kevin B. Urdahl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
To investigate how host and pathogen diversity govern immunity against Mycobacterium tuberculosis (Mtb), we performed a large-scale screen of vaccine-mediated protection against aerosol Mtb infection using three inbred mouse strains [C57BL/6 (B6), C3
Externí odkaz:
https://doaj.org/article/8f1d5d9be6814725a222414224aa913c
Autor:
Johannes Nemeth, Gregory S Olson, Alissa C Rothchild, Ana N Jahn, Dat Mai, Fergal J Duffy, Jared L Delahaye, Sanjay Srivatsan, Courtney R Plumlee, Kevin B Urdahl, Elizabeth S Gold, Alan Aderem, Alan H Diercks
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008655 (2020)
Progress in tuberculosis vaccine development is hampered by an incomplete understanding of the immune mechanisms that protect against infection with Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis. Although the M72/ASOE1 trial y
Externí odkaz:
https://doaj.org/article/8b125e515468469890da614482c96ca1
Autor:
Shahin Shafiani, Kevin B. Urdahl, Michael Y. Gerner, Benjamin H. Gern, Jared L. Delahaye, Sara B. Cohen, Courtney R. Plumlee
Publikováno v:
The Journal of Immunology. 203:807-812
Growing evidence suggests the outcome of Mycobacterium tuberculosis infection is established rapidly after exposure, but how the current tuberculosis vaccine, bacillus Calmette–Guérin (BCG), impacts early immunity is poorly understood. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e8f607f0213323277850d325abbfc2d
https://doi.org/10.4049/jimmunol.1900108
https://doi.org/10.4049/jimmunol.1900108
Autor:
Tige R. Rustad, Courtney R. Plumlee, John D. Aitchison, David R. Sherman, Michael K. Axthelm, Vitaly V. Ganusov, Sara B. Cohen, Caleb R. Stoltzfus, Benjamin H. Gern, Michael Y. Gerner, Fergal J. Duffy, Kevin B. Urdahl, Daniel E. Zak, Scott G. Hansen, Jared L. Delahaye, Louis J. Picker
Publikováno v:
SSRN Electronic Journal.
Tuberculosis (TB) is a highly heterogeneous disease that develops in a subset of individuals infected with aerosolized Mycobacterium tuberculosis (Mtb). We sought to develop an improved experimental model by infecting mice with an ultra-low dose (ULD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42f31bf1ebaa8890d47b4c762972eabc
https://doi.org/10.2139/ssrn.3541362
https://doi.org/10.2139/ssrn.3541362
Autor:
Jared L. Delahaye, Michael Y. Gerner, Kevin B. Urdahl, Benjamin H. Gern, Sara B. Cohen, Courtney R. Plumlee, Shahin Shafiani
Growing evidence suggests the outcome of Mycobacterium tuberculosis (Mtb) infection is established rapidly after exposure, but how the current tuberculosis vaccine, BCG, impacts early immunity is poorly understood. Here we found that murine BCG immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533a1f0857e7885bc6804ad04b599d19
https://doi.org/10.1101/590554
https://doi.org/10.1101/590554
Autor:
Alan Aderem, Alan H. Diercks, Ana N. Jahn, Elizabeth S. Gold, Alissa C. Rothchild, Dat Mai, Johannes Nemeth, Gregory S. Olson, Kevin B. Urdahl, Fergal J. Duffy, Courtney R. Plumlee, Jared L. Delahaye, Sanjay Srivatsan
An efficacious vaccine against adult tuberculosis (TB) remains elusive. Progress is hampered by an incomplete understanding of the immune mechanisms that protect against infection with Mycobacterium tuberculosis (Mtb), the causative agent of TB1. Ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80efa779f5e76e0f8528c8693a51006
Autor:
Jared L, Delahaye, Benjamin H, Gern, Sara B, Cohen, Courtney R, Plumlee, Shahin, Shafiani, Michael Y, Gerner, Kevin B, Urdahl
Publikováno v:
J Immunol
Growing evidence suggests the outcome of Mycobacterium tuberculosis (Mtb) infection is established rapidly after exposure, but how the current tuberculosis vaccine, BCG, impacts early immunity is poorly understood. Here we found that murine BCG immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86566b710ef88693dbf720450ae8b973
https://pubmed.ncbi.nlm.nih.gov/31308091
https://pubmed.ncbi.nlm.nih.gov/31308091
Autor:
Courtney R. Plumlee, John D. Aitchison, Louis J. Picker, Jared L. Delahaye, Michael Y. Gerner, Scott G. Hansen, Tige R. Rustad, Kevin B. Urdahl, Caleb R. Stoltzfus, Benjamin H. Gern, Vitaly V. Ganusov, Sara B. Cohen, Michael K. Axthelm, Daniel E. Zak, David R. Sherman, Fergal J. Duffy
Publikováno v:
Cell Host Microbe
Tuberculosis (TB) is a heterogeneous disease manifesting in a subset of individuals infected with aerosolized Mycobacterium tuberculosis (Mtb). Unlike human TB, murine infection results in uniformly high lung bacterial burdens and poorly organized gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a817e260587633f81dff1bf473e5f665
https://doi.org/10.1016/j.chom.2020.10.003
https://doi.org/10.1016/j.chom.2020.10.003
Autor:
Courtney R Plumlee, Fergal J Duffy, Benjamin H Gern, Jared L Delahaye, Sara B Cohen, Tige R Rustad, John D Aitchison, David R Sherman, Daniel E Zak, Michael Y Gerner, Kevin B Urdahl
Publikováno v:
The Journal of Immunology. 204:231.25-231.25
Tuberculosis (TB) is a highly heterogeneous disease that develops in a subset of individuals infected with aerosolized Mycobacterium tuberculosis (Mtb). To improve upon the standard experimental mouse model, we infected mice with an ultra-low Mtb dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f56a6b35a2bd8668ca41808434d1eeaf
https://doi.org/10.4049/jimmunol.204.supp.231.25
https://doi.org/10.4049/jimmunol.204.supp.231.25
Autor:
Jared L Delahaye, Sara B Cohen, Eliza Peterson, Kristin Adams, Courtney R Plumlee, Christopher Plaisier, Nitin Baliga, Kevin B Urdahl
Publikováno v:
The Journal of Immunology. 204:156.3-156.3
During Mycobacterium tuberculosis (Mtb) infection, bacteria are inhaled into the lung where they first infect resident, alveolar macrophages (AM). The majority of the infection remains in AM until D14, when other cells, including recruited monocyte-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d04696b66967c5304468e21c7d70418
https://doi.org/10.4049/jimmunol.204.supp.156.3
https://doi.org/10.4049/jimmunol.204.supp.156.3