Zobrazeno 1 - 10
of 1 371
pro vyhledávání: '"L Decker"'
Autor:
Christine Rempfer, Sebastian N.W. Hoernstein, Nico van Gessel, Andreas W. Graf, Roxane P. Spiegelhalder, Anne Bertolini, Lennard L. Bohlender, Juliana Parsons, Eva L. Decker, Ralf Reski
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2580-2594 (2024)
Hydroxylation of prolines to 4-trans-hydroxyproline (Hyp) is mediated by prolyl-4 hydroxylases (P4Hs). In plants, Hyps occur in Hydroxyproline-rich glycoproteins (HRGPs), and are frequently O-glycosylated. While both modifications are important, e.g.
Externí odkaz:
https://doaj.org/article/498a1b01e65e490cb7f194d15b8df6ee
Autor:
C. Llaó-Cid, B. Peguera, P. Kobialka, L. Decker, J. Vogenstahl, N. Alivodej, S. Srivastava, J. Jin, B. C. Kirchmaier, C. Milla, H. Schlierbach, A. Schänzer, T. Acker, M. Segarra, A. Acker-Palmer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Veins have emerged as the origin of all other endothelial cell subtypes needed to expand vascular networks during developmental and pathological neoangiogenesis. Here, we uncover the role of the angioneurin Fibronectin Leucine Rich Transmemb
Externí odkaz:
https://doaj.org/article/14fba98695504c01a262fd5e817240f8
Autor:
Rodney L. Decker, C. Steven Ernest II, David B. Radtke, Rona Wang, Joana Araújo, Stuart Y. Keller, Xin Zhang
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 6, Pp 970-981 (2024)
Abstract Baricitinib is approved for the treatment of rheumatoid arthritis (RA) in more than 70 countries, and juvenile idiopathic arthritis (JIA) in the European Union. Population pharmacokinetic (PK) models were developed in a phase 3 trial to char
Externí odkaz:
https://doaj.org/article/cabc28d70a48442d8a69bd4e181985ce
Autor:
Sarah R. Vavrek, Elif Kayaalp Nalbant, PhD, Nicholas Konopek, Nicole L. Decker, Amani A. Fawzi, MD, William F. Mieler, MD, Kenneth M. Tichauer, PhD, Jennifer J. Kang-Mieler, PhD
Publikováno v:
Ophthalmology Science, Vol 5, Iss 2, Pp 100636- (2025)
Objective: To investigate retinal vascular permeability mapping as a potential biomarker for diabetic retinopathy in subjects with diabetes with no signs of retinopathy and with mild nonproliferative retinopathy. Design: This is a case-control study.
Externí odkaz:
https://doaj.org/article/4677d062899a4e32aafc5d432246dd56
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 36, Iss 11, Pp 682-692 (2023)
Oxidative burst, the rapid production of high levels of reactive oxygen species in response to external stimuli, is an early defense reaction against pathogens. The fungal elicitor chitosan causes an oxidative burst in the moss Physcomitrium patens (
Externí odkaz:
https://doaj.org/article/c7a69768f61e4816afcddedf7d7f6325
Autor:
Sherry S. Chesak, Patrick L. Decker-Tonnesen, Ashok Kumbamu, Ivana Croghan, Barbara L. Jordan, Cathryn H. Fraser, John D. Halamka, Charanjit S. Rihal, Gianrico Farrugia, Anjali Bhagra
Publikováno v:
Social Sciences and Humanities Open, Vol 10, Iss , Pp 100881- (2024)
Objective: To evaluate the impact of the Mayo Clinic Reflect, Inspire, Strengthen and Empower (RISE) for Equity national conference on participant healthcare professionals’ knowledge, skills, and attitudes (KSA) related to diversity, equity, and in
Externí odkaz:
https://doaj.org/article/a2966706cebd4831bccf6ebb1acf926e
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1473-1486 (2023)
Human complement is the first line of defence against invading pathogens and is involved in tissue homeostasis. Complement-targeted therapies to treat several diseases caused by a dysregulated complement are highly desirable. Despite huge efforts inv
Externí odkaz:
https://doaj.org/article/1cb2749bacb5487f8b7c32eb72d5cf63
Autor:
Patrick Webb, Kara Livingston Staffier, Hyomin Lee, Brian Howell, Kyra Battaglia, Brooke M. Bell, Julia Matteson, Nicola M. McKeown, Sean B. Cash, Fang Fang Zhang, Jessica L. Decker Sparks, Nicole Tichenor Blackstone
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
IntroductionResearch on the impacts of dietary patterns on human and planetary health is a rapidly growing field. A wide range of metrics, datasets, and analytical techniques has been used to explore the role of dietary choices/constraints in driving
Externí odkaz:
https://doaj.org/article/c800ddb4174142d0ba4dc3d99032a8b6
Autor:
Elizabeth R. Selig, Shinnosuke Nakayama, Colette C. C. Wabnitz, Henrik Österblom, Jessica Spijkers, Nathan A. Miller, Jan Bebbington, Jessica L. Decker Sparks
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Taking action to reduce risks of labor abuse and illegal, unreported, and unregulated (IUU) fishing in the fishing sector is hindered by a lack of spatially explicit data and an understanding of different drivers of risks. Here the authors combine ex
Externí odkaz:
https://doaj.org/article/28f260005000435ea76fdc2a875c1b1e
Autor:
Natalia Ruiz-Molina, Juliana Parsons, Madeleine Müller, Sebastian N. W. Hoernstein, Lennard L. Bohlender, Steffen Pumple, Peter F. Zipfel, Karsten Häffner, Ralf Reski, Eva L. Decker
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Ruiz-Molina et al. design a synthetic protein, MFHR13, as a multi-target complement regulator. They demonstrate that it protects sheep erythrocytes from complement attack exhibiting 26 and 4-fold the regulatory activity of eculizumab and human Factor
Externí odkaz:
https://doaj.org/article/0d939a14797d46a4b48d77263b3814c8