Zobrazeno 1 - 10
of 21
pro vyhledávání: '"L DeEtte Walker"'
Autor:
Shubin W Shahab, Lilya V Matyunina, Roman Mezencev, L DeEtte Walker, Nathan J Bowen, Benedict B Benigno, John F McDonald
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22508 (2011)
MicroRNAs (miRNAs) are short (∼22 nucleotides) regulatory RNAs that can modulate gene expression and are aberrantly expressed in many diseases including cancer. Previous studies have shown that miRNAs inhibit the translation and facilitate the degr
Externí odkaz:
https://doaj.org/article/b68aae28e5354e80b6533ef8e46bfd42
Autor:
Mengnan Zhang, Lilya V. Matyunina, L. DeEtte Walker, Weixuan Chen, Haopeng Xiao, Benedict B. Benigno, Ronghu Wu, John F. McDonald
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract High-throughput technologies have identified significant changes in patterns of mRNA expression over cancer development but the functional significance of these changes often rests upon the assumption that observed changes in levels of mRNA
Externí odkaz:
https://doaj.org/article/7897ad282e104afabe0c3c6fd98e370c
Autor:
John F. McDonald, Facundo M. Fernández, Alexander Gray, Benedict B. Benigno, Roman Mezencev, L. DeEtte Walker, Wei Guan, Manshui Zhou
Supplementary Figures 1-5, Supplementary Tables 1-2 from Rapid Mass Spectrometric Metabolic Profiling of Blood Sera Detects Ovarian Cancer with High Accuracy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e8839329e0d28d5b5226fc75e3234c
https://doi.org/10.1158/1055-9965.22435762.v1
https://doi.org/10.1158/1055-9965.22435762.v1
Autor:
John F. McDonald, Facundo M. Fernández, Alexander Gray, Benedict B. Benigno, Roman Mezencev, L. DeEtte Walker, Wei Guan, Manshui Zhou
Background: Ovarian cancer diagnosis is problematic because the disease is typically asymptomatic, especially at the early stages of progression and/or recurrence. We report here the integration of a new mass spectrometric technology with a novel sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2acdf759f426654c6a9698290f612d37
https://doi.org/10.1158/1055-9965.c.6515089
https://doi.org/10.1158/1055-9965.c.6515089
Autor:
L. DeEtte Walker, Lilya V. Matyunina, Benedict B. Benigno, Haopeng Xiao, Weixuan Chen, Ronghu Wu, John F. McDonald, Mengnan Zhang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
High-throughput technologies have identified significant changes in patterns of mRNA expression over cancer development but the functional significance of these changes often rests upon the assumption that observed changes in levels of mRNA accuratel
Autor:
Facundo M. Fernández, Manshui Zhou, Xiaoling Zang, Roman Mezencev, Tran Q. Long, Alexander G. Gray, Christina M. Jones, L. DeEtte Walker, John F. McDonald, María Eugenia Monge
Publikováno v:
Journal of Proteome Research. 13:3444-3454
Prostate cancer (PCa) is the second leading cause of cancer-related mortality in men. The prevalent diagnosis method is based on the serum prostate-specific antigen (PSA) screening test, which suffers from low specificity, overdiagnosis, and overtrea
Publikováno v:
Pancreas
Supplemental digital content is available in the text.
Objectives There is a growing body of evidence that targeted gene therapy holds great promise for the future treatment of cancer. A crucial step in this therapy is the accurate identificatio
Objectives There is a growing body of evidence that targeted gene therapy holds great promise for the future treatment of cancer. A crucial step in this therapy is the accurate identificatio
Autor:
L. DeEtte Walker, Yu Wei Chou, Subodh M. Lele, Te Jung Tsai, Benedict B. Benigno, Shafiq A. Khan, Sakthivel Muniyan, John F. McDonald, Fen Fen Lin, Ming Fong Lin, Paul G. Thomes, Suresh Veeramani
Publikováno v:
Molecular Carcinogenesis. 54:618-631
p66Shc functions as a longevity protein in murine and exhibits oxidase activity in regulating diverse biological activities. In this study, we investigated the role of p66Shc protein in regulating ovarian cancer (OCa) cell proliferation. Among three
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2013 (2013)
BioMed Research International, Vol 2013 (2013)
Although stromal cell signaling has been shown to play a significant role in the progression of many cancers, relatively little is known about its importance in modulating ovarian cancer development. The purpose of this study was to investigate the p
Autor:
Vinay K. Mittal, John F. McDonald, Shubin W. Shahab, Lijuan Wang, Parker H. Petit, L. DeEtte Walker, Lilya V. Matyunina, Christopher G. Hill
Publikováno v:
British Journal of Medicine and Medical Research. 2:172-194
MicroRNAs (miRNAs) are a class of regulatory RNAs that control the expression of genes critical to cell function. Ectopic expression of miRNAs has been shown to result in genome-wide changes in patterns of gene expression. While the reasons for these