Zobrazeno 1 - 10
of 362
pro vyhledávání: '"L David Sibley"'
Autor:
Paul Kelly, William A Petri, Rashidul Haque, Ibrahim A Khalil, Lynn Barrett, Tom Kennedy, Timothy Wells, Christopher D Huston, James Platts-mills, Grace S Yang, Richard Omore, Ian H Gilbert, Sumiti Vinayak, Boris Striepen, Ujjini H Manjunatha, Wesley C Van Voorhis, Samuel L M Arnold, Beatriz Baragana, Frederick S Buckner, Jeremy D Burrows, Maria A Caravedo, Ryan Choi, Robert K M Choy, Eugenio de Hostos, Thierry Diagana, Suzanne Duce, Matthew A Hulverson, Pui-Ying Iroh Tam, Minju Kim, Poonum Korpe, Benoît Laleu, Diana Lalika, Fabrice Laurent, Case W McNamara, Marvin J Meyers, Roberta M O’Connor, Kayode K Ojo, Philipp Olias, Nede Ovbiebo, Mattie C Pawlowic, Gladys Queen, Divya Rao, Kevin Reed, Michael W Riggs, Jennifer L Roxas, Adam Sateriale, Deborah A Schaefer, L David Sibley, Jonathan M Spector, Chris Tonkin, Timilehin E Toye, Saul Tzipori, A Clinton White
Publikováno v:
BMJ Global Health, Vol 8, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/540e409047fd43baae051b1737c1bbc5
Publikováno v:
eLife, Vol 10 (2021)
Toxoplasma gondii has evolved different developmental stages for disseminating during acute infection (i.e., tachyzoites) and establishing chronic infection (i.e., bradyzoites). Calcium ion (Ca2+) signaling tightly regulates the lytic cycle of tachyz
Externí odkaz:
https://doaj.org/article/36825b911eff45ed9701b6ee6fca8109
Autor:
Nicholas Rinkenberger, Michael E Abrams, Sumit K Matta, John W Schoggins, Neal M Alto, L David Sibley
Publikováno v:
eLife, Vol 10 (2021)
Toxoplasma gondii is an important human pathogen infecting an estimated one in three people worldwide. The cytokine interferon gamma (IFNγ) is induced during infection and is critical for restricting T. gondii growth in human cells. Growth restricti
Externí odkaz:
https://doaj.org/article/f9a094b9feae4b0d9982f05ca988a55a
Autor:
Eugene Park, Swapneel Patel, Qiuling Wang, Prabhakar Andhey, Konstantin Zaitsev, Sophia Porter, Maxwell Hershey, Michael Bern, Beatrice Plougastel-Douglas, Patrick Collins, Marco Colonna, Kenneth M Murphy, Eugene Oltz, Maxim Artyomov, L David Sibley, Wayne M Yokoyama
Publikováno v:
eLife, Vol 8 (2019)
Innate lymphoid cells (ILCs) were originally classified based on their cytokine profiles, placing natural killer (NK) cells and ILC1s together, but recent studies support their separation into different lineages at steady-state. However, tumors may i
Externí odkaz:
https://doaj.org/article/c19f92493fd848258bcc56fac6cfff09
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006379 (2017)
Toxoplasma gondii contains an expanded number of calmodulin (CaM)-like proteins whose functions are poorly understood. Using a combination of CRISPR/Cas9-mediated gene editing and a plant-like auxin-induced degron (AID) system, we examined the roles
Externí odkaz:
https://doaj.org/article/fe4c32b1576e4fcabba4f572aa73a7cc
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006272 (2017)
The Toxoplasma gondii genome contains two aromatic amino acid hydroxylase genes, AAH1 and AAH2 encode proteins that produce L-DOPA, which can serve as a precursor of catecholamine neurotransmitters. It has been suggested that this pathway elevates ho
Externí odkaz:
https://doaj.org/article/b672c2bef3e84b88907aa2758f58a3a3
Autor:
Francois Peyron, Rima Mc Leod, Daniel Ajzenberg, Despina Contopoulos-Ioannidis, François Kieffer, Laurent Mandelbrot, L David Sibley, Hervé Pelloux, Isabelle Villena, Martine Wallon, Jose G Montoya
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005222 (2017)
Externí odkaz:
https://doaj.org/article/3b74e32e59534078a505a10e3daeeb4f
Autor:
John R Jimah, Nichole D Salinas, Monica Sala-Rabanal, Nathaniel G Jones, L David Sibley, Colin G Nichols, Paul H Schlesinger, Niraj H Tolia
Publikováno v:
eLife, Vol 5 (2016)
Apicomplexan parasites contain a conserved protein CelTOS that, in malaria parasites, is essential for traversal of cells within the mammalian host and arthropod vector. However, the molecular role of CelTOS is unknown because it lacks sequence simil
Externí odkaz:
https://doaj.org/article/0d27362f7380472ca59ba61e6e16c97f
Autor:
Michael S Behnke, Asis Khan, Elvin J Lauron, John R Jimah, Qiuling Wang, Niraj H Tolia, L David Sibley
Publikováno v:
PLoS Genetics, Vol 11, Iss 8, p e1005434 (2015)
Toxoplasma gondii has evolved a number of strategies to evade immune responses in its many hosts. Previous genetic mapping of crosses between clonal type 1, 2, and 3 strains of T. gondii, which are prevalent in Europe and North America, identified tw
Externí odkaz:
https://doaj.org/article/1fa8760ff641441e81f56d76ddda271b
Autor:
Tobias Steinfeldt, Stephanie Könen-Waisman, Lan Tong, Nikolaus Pawlowski, Tobias Lamkemeyer, L David Sibley, Julia P Hunn, Jonathan C Howard
Publikováno v:
PLoS Biology, Vol 13, Iss 7, p e1002199 (2015)
Externí odkaz:
https://doaj.org/article/5445ed2622f34cc5b66a1f5f4b2d5c4c