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Developmental neurotoxicity evaluation of acrylamide in Sprague-Dawley rats

Autor: L. D. Wise, K A Soper, L R Gordon, R E Morrissey, D M Duchai

Publikováno v: Neurotoxicology and Teratology. 17:189-198

Based on the literature to-date, the potential of acrylamide (ACRL) to cause developmental neurotoxicity in laboratory animals has not been assessed. We examined this potential in Sprague-Dawley rats using a study design similar to that proposed by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004e95ec79a4f0f9c80d81cb0a7b405b
https://doi.org/10.1016/0892-0362(94)00071-k

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Reversible effects of triamcinolone and lack of effects with aspirin or L-656,224 on external genitalia of male Sprague-Dawley rats exposed in utero

Autor: C M Vetter, Charles A. Anderson, L. D. Wise, Robert L Clark, Joseph M. Antonello

Publikováno v: Teratology. 44:507-520

Inhibitors of the arachidonic acid cascade were given to pregnant rats during the critical period for morphogenesis of the external genitalia. Groups treated subcutaneously (s.c.) with 0.1 or 0.25 mg/kg/day of triamcinolone acetonide (TA) on gestatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3403f2d269154fb60f7cc44a836ef2bf
https://doi.org/10.1002/tera.1420440505

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Examination of a rodent limb bud micromass assay as a prescreen for developmental toxicity

Autor: J. O. Rundell, Robert L Clark, R. T. Robertson, L. D. Wise

Publikováno v: Teratology. 41:341-351

The mouse limb bud micromass assay is one of many short-term tests proposed as preliminary screens for potential developmental toxicity. Previous efforts to validate this assay have used too few "nonteratogens." The purpose of this study was to exami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c07ba0522423442581637226f56fc0f
https://doi.org/10.1002/tera.1420410312

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Synthesis and pharmacological evaluation of thiopyran analogues of the dopamine D3 receptor-selective agonist (4aR,10bR)-(+)-trans-3,4,4a,10b-tetrahydro-4-n-propyl-2H,5H [1]b enzopyrano[4,3-b]-1,4-oxazin-9-ol (PD 128907)

Autor: L A, van Vliet, N, Rodenhuis, D, Dijkstra, H, Wikström, T A, Pugsley, K A, Serpa, L T, Meltzer, T G, Heffner, L D, Wise, M E, Lajiness, R M, Huff, K, Svensson, S, Sundell, M, Lundmark

Publikováno v: Journal of medicinal chemistry. 43(15)

Benzopyranoxazine (+)-7 (PD 128907) is the most dopamine (DA) D3 receptor-selective agonist presently known. The only structural feature which distinguishes 7 from the analogous nonselective naphthoxazines is an oxygen atom in the 6-position. To exte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::782735ee7101d97d5722e9d202f6bd4b
https://pubmed.ncbi.nlm.nih.gov/10956195

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Developmental neurotoxicity evaluation of the avermectin pesticide, emamectin benzoate, in Sprague-Dawley rats

Autor: R. J. Gerson, D. R. Verbeke, H. L. Allen, L. D. Wise, C.-M. L. Hoe

Publikováno v: Neurotoxicology and teratology. 19(4)

The potential of emamectin benzoate (EB) to cause developmental neurotoxicity in Sprague-Dawley rats was assessed using a study design by the US EPA. Dosages of 0 (deionized water), 0.1, 0.6, or 3.6 mg/kg/day were administered at 5 ml/kg by oral gava

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932ad42f323cb8cc910c81bebd420774
https://pubmed.ncbi.nlm.nih.gov/9253010

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Terminology of developmental abnormalities in common laboratory mammals (version 1)

Autor: L D, Wise, S L, Beck, D, Beltrame, B K, Beyer, I, Chahoud, R L, Clark, R, Clark, A M, Druga, M H, Feuston, P, Guittin, S M, Henwood, C A, Kimmel, P, Lindstrom, A K, Palmer, J A, Petrere, H M, Solomon, M, Yasuda, R G, York

Publikováno v: Teratology. 55(4)

This paper presents the first version of an internationally-developed glossary of terms for structural developmental abnormalities in common laboratory animals. The glossary is put forward by the International Federation of Teratology Societies (IFTS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a87650ee6b80d66e00cfbe82d98ccfc
https://pubmed.ncbi.nlm.nih.gov/9216042

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Methods for assessing sperm motility, morphology, and counts in the rat, rabbit, and dog: a consensus report. ILSI Risk Science Institute Expert Working Group on Sperm Evaluation

Autor: J, Seed, R E, Chapin, E D, Clegg, L A, Dostal, R H, Foote, M E, Hurtt, G R, Klinefelter, S L, Makris, S D, Perreault, S, Schrader, D, Seyler, R, Sprando, K A, Treinen, D N, Veeramachaneni, L D, Wise

Publikováno v: Reproductive toxicology (Elmsford, N.Y.). 10(3)

Reproductive toxicity studies are increasingly including assessments of sperm parameters including motility, morphology, and counts. While these assessments can provide valuable information for the determination of potential reproductive toxicity, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::19e270902a0a4861a0e761228075596b
https://pubmed.ncbi.nlm.nih.gov/8738562

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CI-1007, a dopamine partial agonist and potential antipsychotic agent. II. Neurophysiological and behavioral effects

Autor: L T, Meltzer, C L, Christoffersen, A E, Corbin, F W, Ninteman, K A, Serpa, J N, Wiley, L D, Wise, T G, Heffner

Publikováno v: The Journal of pharmacology and experimental therapeutics. 274(2)

CI-1007 has been described in receptor binding and biochemical tests as a dopamine (DA) partial agonist that exhibits DA autoreceptor agonist effects. The present studies describe the profile of CI-1007 in electrophysiological and behavioral tests. C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76158987fd3019acab7f2e2df9ef8286
https://pubmed.ncbi.nlm.nih.gov/7636754

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