Zobrazeno 1 - 10
of 12
pro vyhledávání: '"L D Stratford-Perricaudet"'
Autor:
Jacques Piette, L D Stratford-Perricaudet, Jean-Louis Bessereau, Jean-Pierre Changeux, C Le Poupon
Publikováno v:
Proceedings of the National Academy of Sciences. 91:1304-1308
Acetylcholine receptor (AChR) genes are repressed in extrajunctional domains of adult muscle fiber by neurally evoked electrical activity. Denervation elicits upregulation of AChR gene transcription in extrasynaptic areas. We have used an adenovirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edde6b15334ddeb16a99b91c2b16435a
https://doi.org/10.1073/pnas.91.4.1304
https://doi.org/10.1073/pnas.91.4.1304
Autor:
Michel Perricaudet, Ronald G. Crystal, J P Lecocq, Melissa A. Rosenfeld, Andrea Pavirani, Andrea Mastrangeli, Claire Danel, L D Stratford-Perricaudet
Publikováno v:
Journal of Clinical Investigation. 91:225-234
A variety of pulmonary disorders, including cystic fibrosis, are potentially amenable to treatment in which a therapeutic gene is directly transferred to the bronchial epithelium. This is difficult to accomplish because the majority of airway epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cd4a904c6d548e61ff5c3334bae694
https://doi.org/10.1172/jci116175
https://doi.org/10.1172/jci116175
Autor:
L D Stratford-Perricaudet, Koichi Yoneyama, Ronald G. Crystal, L Stier, Paavo K. Paakko, Wolfgang Siegfried, Melissa A. Rosenfeld, Jean-Pierre Lecocq, Sophie Jallat, Michel Perricaudet, Pascale Gilardi, Kunihiko Yoshimura, Masashi Fukayama, Andrea Pavirani
Publikováno v:
Science. 252:431-434
The respiratory epithelium is a potential site for somatic gene therapy for the common hereditary disorders alpha 1-antitrypsin (alpha 1AT) deficiency and cystic fibrosis. A replication-deficient adenoviral vector (Ad-alpha 1AT) containing an adenovi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994dfe695648dac65a9583fa671e0e45
https://doi.org/10.1126/science.2017680
https://doi.org/10.1126/science.2017680
Autor:
W Siegfried, Michel Perricaudet, Melissa A. Rosenfeld, L D Stratford-Perricaudet, L Stier, Andrea Pavirani, J P Lecocq, Ronald G. Crystal
Publikováno v:
American journal of respiratory cell and molecular biology. 12(4)
alpha 1-Antitrypsin (alpha AT) deficiency, a hereditary cause of progressive emphysema, can potentially be treated by transfer of a functional human alpha 1AT gene to the respiratory epithelium. For such an approach to be successful, alpha 1AT must b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4801e553127579215075411b43a901bb
https://pubmed.ncbi.nlm.nih.gov/7695917
https://pubmed.ncbi.nlm.nih.gov/7695917
Publikováno v:
Bulletin de l'Academie nationale de medecine. 179(3)
Due to their quiescent nature and spatial complexity, many target tissues for gene therapy will require novel strategies. An alternative to ex vivo gene transfer, providing many technical advantages and possibly allowing sufficient transfer of the th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5dcb770a70ae15dd50c0c0da05e9507a
https://pubmed.ncbi.nlm.nih.gov/7648295
https://pubmed.ncbi.nlm.nih.gov/7648295
Autor:
K F, Kozarsky, D R, McKinley, L L, Austin, S E, Raper, L D, Stratford-Perricaudet, J M, Wilson
Publikováno v:
The Journal of biological chemistry. 269(18)
A rabbit animal model of the human disease familial hypercholesterolemia (FH), which is the result of low density lipoprotein (LDL) receptor deficiency, was used to develop an in vivo approach to gene therapy based on recombinant adenoviruses. Recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f0ad5a255c4a01b14dd7a7b071f2f46
https://pubmed.ncbi.nlm.nih.gov/8175805
https://pubmed.ncbi.nlm.nih.gov/8175805
Autor:
J, Mallet, G, Le Gal La Salle, J J, Robert, S, Berrard, V, Ridoux, L D, Stratford-Perricaudet, M, Perricaudet
Publikováno v:
Gene therapy. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de12572a75b83074204d56d35fccf110
https://pubmed.ncbi.nlm.nih.gov/8542398
https://pubmed.ncbi.nlm.nih.gov/8542398
Autor:
T, Ragot, L D, Stratford-Perricaudet, N, Vincent, P, Chafey, E, Vigne, H, Gilgenkrantz, D, Couton, P, Briand, J C, Kaplan, A, Kahn
Publikováno v:
Gene therapy. 1
Due to their quiescent nature and spatial complexity, many target tissues for gene therapy will require novel strategies. An alternative to ex vivo gene transfer, providing many technical advantages and possibly allowing sufficient transfer of the th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd7b7e2c424ece2a17bf9561bf4fc73a
https://pubmed.ncbi.nlm.nih.gov/8542399
https://pubmed.ncbi.nlm.nih.gov/8542399
Autor:
G. Le Gal La Salle, J. J. Robert, S. Berrard, V. Ridoux, L. D. Stratford-Perricaudet, M. Perricaudet, J. Mallet
Publikováno v:
Science
Science, American Association for the Advancement of Science, 1993, 259 (5097), pp.988-990. ⟨10.1126/science.8382374⟩
Science, 1993, 259 (5097), pp.988-990. ⟨10.1126/science.8382374⟩
Science, American Association for the Advancement of Science (AAAS), 1993, 259 (5097), pp.988-990. ⟨10.1126/science.8382374⟩
Science, American Association for the Advancement of Science, 1993, 259 (5097), pp.988-990. ⟨10.1126/science.8382374⟩
Science, 1993, 259 (5097), pp.988-990. ⟨10.1126/science.8382374⟩
Science, American Association for the Advancement of Science (AAAS), 1993, 259 (5097), pp.988-990. ⟨10.1126/science.8382374⟩
The efficient introduction of genetic material into quiescent nerve cells is important in the study of brain function and for gene therapy of neurological disorders. A replication-deficient adenoviral vector that contained a reporter gene encoding be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c48bd8d5c3b787bd45c20d7bdc98fa3
https://hal.archives-ouvertes.fr/hal-02920250
https://hal.archives-ouvertes.fr/hal-02920250
Publikováno v:
The Journal of clinical investigation. 90(2)
Successful treatment of muscular disorders awaits an adapted gene delivery protocol. The clinically applicable technique used for hematopoietic cells which is centered around implantation of retrovirally modified cells may not prove sufficient for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393e8cfd9814cef7e5afa37f74fb04d6
https://pubmed.ncbi.nlm.nih.gov/1644927
https://pubmed.ncbi.nlm.nih.gov/1644927