Zobrazeno 1 - 9
of 9
pro vyhledávání: '"L D Klaman"'
Autor:
S. Will, L. Kung, L. D. Klaman, J. F. Tobin, S. Tam, Douglas P. Wilson, Julie Lee, Zhao-Kui Wan, S. Wang, D. V. Erbe, Steven J. Kirincich, X. Xu
Publikováno v:
Diabetes, Obesity and Metabolism. 11:579-588
A growing percentage of the population is resistant to two key hormones - insulin and leptin - as a result of increased obesity, often leading to significant health consequences such as type 2 diabetes. Protein tyrosine phosphatase 1B (PTP1B) is a ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd21831b6f15fc4f865f070c1edfca2b
https://doi.org/10.1111/j.1463-1326.2008.01022.x
https://doi.org/10.1111/j.1463-1326.2008.01022.x
Publikováno v:
The Journal of Immunology. 156:1038-1046
In addition to the content of germ-line variable gene segments, the organization of V genes has been implicated in the development of the Ab repertoire. We have searched the expressed VH genes of BALB/c mice for additional VH gene families and utiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab365fc0052f505b4b1275865080c8c2
https://doi.org/10.4049/jimmunol.156.3.1038
https://doi.org/10.4049/jimmunol.156.3.1038
Publikováno v:
Journal of virology. 70(5)
Epstein-Barr virus infects resting B cells in vitro and activates them to continuously proliferating lymphoblasts. Activation is essential for the virus to convert its linear genome to the covalently closed circular episomal form in which it persists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5478c36dad92a820828deedda0cb68
https://pubmed.ncbi.nlm.nih.gov/8627812
https://pubmed.ncbi.nlm.nih.gov/8627812
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(3)
In addition to the content of germ-line variable gene segments, the organization of V genes has been implicated in the development of the Ab repertoire. We have searched the expressed VH genes of BALB/c mice for additional VH gene families and utiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e5c8ebdee8ae15224560440ee6abd6c
https://pubmed.ncbi.nlm.nih.gov/8557977
https://pubmed.ncbi.nlm.nih.gov/8557977
Autor:
David A. Thorley-Lawson, L D Klaman
Epstein-Barr virus (EBV) infection of mature, resting B cells drives them to become lymphoblasts expressing high levels of cell surface molecules, such as CD48, characteristically expressed on normal activated B cells. Here, we report on the identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d089b9a0ce87d10768e2413bf57d428c
https://europepmc.org/articles/PMC188654/
https://europepmc.org/articles/PMC188654/
Autor:
Shinkichi Yokoyama, Christopher J. Ianelli, Donald E. Staunton, David A. Thorley-Lawson, L D Klaman
Publikováno v:
Biochemical Society transactions. 21(4)
12. Calabi, C., Yu, C. Y., Bisland, C. A. G. and Milstein, C. (1991) in Immunogenetics of the Major Histocompatibility Complex (Srivastava, R.. Ram, B. P. and Tyle, IJ., eds.), pp. 215-243, VCH Press, New York 13. Peterson, 1’. A., Cunningham, B. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10735ccbd432b13073d5191c7d372227
https://pubmed.ncbi.nlm.nih.gov/8132103
https://pubmed.ncbi.nlm.nih.gov/8132103
Publikováno v:
Virology. 185(2)
We have examined the frequency of episome formation in resting B cells 36 hr after infection with Epstein-Barr virus. We have detected an average of 0.65 episomal genomes per cell (SD 0.17). We have used this information to predict the distribution o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1535c0314ba6bf03e30eb62755e1e097
https://pubmed.ncbi.nlm.nih.gov/1660206
https://pubmed.ncbi.nlm.nih.gov/1660206
Publikováno v:
Journal of virology. 65(7)
IB4 is a prototype, latently Epstein-Barr virus (EBV)-infected, lymphoblastoid cell line. We show here that IB4 contains only integrated EBV genomes. Episomal EBV DNA is not detected by Gardella gel analysis or in situ hybridization. Restriction enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39861c8746dab8bb7c1ad9237f3c8758
https://pubmed.ncbi.nlm.nih.gov/1645805
https://pubmed.ncbi.nlm.nih.gov/1645805
Publikováno v:
Diabetes, Obesity and Metabolism. :061114070231001
Aim: Myostatin, a member of the TGF-beta superfamily, is produced by skeletal muscle and acts as a negative regulator of muscle mass. It has also been suggested that low-dose administration of myostatin (2 μg/day) in rodents can reduce fat mass with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382b5fd6349dd5524e8fd5d067a8515c
https://doi.org/10.1111/j.1463-1326.2006.00672.x
https://doi.org/10.1111/j.1463-1326.2006.00672.x