Zobrazeno 1 - 10 of 45 pro vyhledávání: '"L D, Traber"'
1
Role of Nitric Oxide in Vascular Permeability after Combined Burns and Smoke Inhalation Injury
Autor: K, Soejima, L D, Traber, F C, Schmalstieg, H, Hawkins, J M, Jodoin, C, Szabo, E, Szabo, L, Virag, A, Salzman, D L, Traber, L, Varig
Publikováno v: American Journal of Respiratory and Critical Care Medicine. 163:745-752
Patients with severe burn and/or smoke inhalation injury suffer both systemic and pulmonary vascular hyperpermeability. We hypothesized that nitric oxide (NO) produced by inducible nitric oxide synthase (iNOS) plays a role in the changes in microvasc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1431919a0015964ed69cc9e03c6e523
https://doi.org/10.1164/ajrccm.163.3.9912052
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2
Administration of a synthetic antiprotease reduces smoke-induced lung injury
Autor: J. T. Flynn, David Herndon, R. Kimura, Daniel L. Traber, G. D. Niehaus, L. D. Traber
Publikováno v: Journal of Applied Physiology. 69:694-699
Our previous studies suggest that a neutrophil-mediated inflammatory injury causes a major fraction of the pulmonary edema that occurs after smoke inhalation. Because activated neutrophils extrude cytotoxic proteases, the current study was conducted
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c26ce800fbd16334b2ede34f8bfdc8
https://doi.org/10.1152/jappl.1990.69.2.694
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5
Hypoxic Pulmonary Vasoconstriction and the Pulmonary Microcirculation
Autor: D. L. Traber, L. D. Traber
Publikováno v: Yearbook of Intensive Care and Emergency Medicine 2002 ISBN: 9783540431497
Intensive Care Medicine ISBN: 9781475755534
In a normal individual, pulmonary arterial blood is diverted from alveoli that are not being ventilated and perfuses the alveoli that are being ventilated [1, 2]. The mechanism that is responsible for this physiological shunt in blood flow is called
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3871ee2eef57293c2c7d09ac28eb16c5
https://doi.org/10.1007/978-3-642-56011-8_8
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6
Noradrenaline and nomega-monomethyl-L-arginine (L-NMMA): effects on haemodynamics and regional blood flow in healthy and septic sheep
Autor: M, Booke, F, Hinder, R, McGuire, L D, Traber, D L, Traber
Publikováno v: Clinical science (London, England : 1979). 98(2)
This prospective, non-randomized, controlled experimental study looks at the effects of N(omega)-monomethyl-L-arginine (L-NMMA) on haemodynamics, oxygen transport and regional blood flow in healthy and septic sheep, and compares these effects with th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b5f7d61e7a4128944122a8b92005b83
https://pubmed.ncbi.nlm.nih.gov/10657275
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7
Effect of severe smoke inhalation injury on systemic microvascular blood flow in sheep
Autor: P J, Schenarts, H G, Bone, L D, Traber, D L, Traber
Publikováno v: Shock (Augusta, Ga.). 6(3)
Multiple nonpulmonary organ dysfunction is frequently associated with acute lung injury; however, the mechanisms underlying the pathogenesis of this process are not completely understood. Decreased oxygen delivery to distant organs due to maldistribu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aeaf1567cd317ab5596d67aad2576ed1
https://pubmed.ncbi.nlm.nih.gov/8885086
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8
Use of nitric oxide synthase inhibitors in animal models of sepsis
Autor: M, Booke, J, Meyer, W, Lingnau, F, Hinder, L D, Traber, D L, Traber
Publikováno v: New horizons (Baltimore, Md.). 3(1)
Sepsis, as a general inflammatory process, affects the whole organism, mainly because of the intense vasodilation and reduced perfusion pressures associated with it. The high mortality rates seen with sepsis are correlated with a reduction in mean ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1402c2b27b60831e783cd5270080e495
https://pubmed.ncbi.nlm.nih.gov/7535647
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9
Endotoxin versus bacteremia: a comparison focusing on clinical relevance
Autor: M, Booke, W, Lingnau, F, Hinder, L D, Traber, D L, Traber
Publikováno v: Progress in clinical and biological research. 392
All phenomena seen under ovine endotoxemia or bacteremia are typically observed in septic humans as well. The lethality (approximately 20%) in both sepsis models underlines the severity of the experimental sepsis in these models. As mentioned above,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df7fb51bc3d64e81f27285c85c354da9
https://pubmed.ncbi.nlm.nih.gov/8524947
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10
Heparin improves oxygenation and minimizes barotrauma after severe smoke inhalation in an ovine model
Autor: C S, Cox, J B, Zwischenberger, D L, Traber, L D, Traber, A K, Haque, D N, Herndon
Publikováno v: Surgery, gynecologyobstetrics. 176(4)
Inhalation injury is one of the main causes of mortality in burn victims. The tracheobronchial epithelium sloughs and combines with a protein rich exudate to form casts of the airways that can lead to obstruction. We studied the effects of a continuo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3a01b5074b12924f2998c704bd411e99
https://pubmed.ncbi.nlm.nih.gov/8460409
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