Zobrazeno 1 - 4
of 4
pro vyhledávání: '"L D, Artman"'
Publikováno v:
Pharmaceutical research. 15(1)
Twelve synthetic spider toxin analogs were prepared in an effort to better understand the structure-activity relationships of the polyamine portion of argiotoxin-636 (Arg-636), a noncompetitive NMDA receptor (NMDAR) antagonist.The 1,13-diamino-4,8-di
Autor:
T N, Parks, A L, Mueller, L D, Artman, B C, Albensi, E F, Nemeth, H, Jackson, V J, Jasys, N A, Saccomano, R A, Volkmann
Publikováno v:
The Journal of biological chemistry. 266(32)
The venom of the North American funnel-web spider Agelenopsis aperta contains a variety of arylamine toxins (the alpha-agatoxins) that paralyze insects by blocking glutamatergic neuromuscular transmission. We have tested six synthetic alpha-agatoxins
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 218(2)
The development of tolerance to cholinergic agonists such as oxotremorine is a well established phenomenon. The hypothesis that such tolerance may be explained by a decrease in the number of affinity of muscarinic receptors was tested by chronically
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 62(2)
We studied the effects of regional hypoxic pulmonary vasoconstriction (HPV) on lobar flow diversion in the presence of hydrostatic pulmonary edema. Ten anesthetized dogs with the left lower lobe (LLL) suspended in a net for continuous weighing were v