Zobrazeno 1 - 7
of 7
pro vyhledávání: '"L D, Altstiel"'
Autor:
E. J. Holsztynska, K. L. Sacchi, L. Z. Chen, J. C. Clemens, I. M. Lieberburg, L. C. Mutter, Bruce D. Gitter, T. C. Britton, C. A. Whitesitt, E. D. Thorsett, L. D. Altstiel, M. H. Bender, K. L. Johnson-Wood, G. M. Shopp, R. N. Motter, B. Folmer, T. E. Mabry, D. Stephenson, S. Yang, B. D. Potts, Binhui Ni, D. B. Schenk, T. Yin, Paul A. Hyslop, Jon K. Reel, K. L. Hu, W.-Y. Li, C. T. Yin, J. E. Knops, P. De Saint Andrieu, V. John, Z. Liao, E. Goldbach, F. D. Miller, L. A. Shipley, J. Wu, E. M. Johnstone, L. H. Latimer, S. B. Freedman, J. P. Anderson, H. F. Dovey, P. A. Seubert, Michael K. Lee, D. K. Dieckman-Mcginty, S. L. Kennedy, J. S. Nissen, Sheila P. Little, Leonard N. Boggs, J. S. Tung, J. Nietz, L. Y. Fang, D. L. Czilli, Patrick C. May, Warren J. Porter, James E. Audia, K. P. Quinn, J. J. Droste, D. Kholodenko, Y. Su, Kimberly S. Fuson
Publikováno v:
Journal of Neurochemistry. 76:173-181
Converging lines of evidence implicate the beta-amyloid peptide (Ass) as causative in Alzheimer's disease. We describe a novel class of compounds that reduce A beta production by functionally inhibiting gamma-secretase, the activity responsible for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630a5e68d7d06683f0b9a3afbc3d4a0e
https://doi.org/10.1046/j.1471-4159.2001.00012.x
https://doi.org/10.1046/j.1471-4159.2001.00012.x
Autor:
L. D. Altstiel
Publikováno v:
Alzheimer disease and associated disorders. 16
The major barrier to Alzheimer disease (AD) drug discovery and development in the biotechnology industry is scale. Most biotechnology companies do not have the personnel or expertise to carry a drug from the bench to the market. Much effort in the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d108bbc90863ef60a68bda64249207a
https://pubmed.ncbi.nlm.nih.gov/12070359
https://pubmed.ncbi.nlm.nih.gov/12070359
Autor:
H F, Dovey, V, John, J P, Anderson, L Z, Chen, P, de Saint Andrieu, L Y, Fang, S B, Freedman, B, Folmer, E, Goldbach, E J, Holsztynska, K L, Hu, K L, Johnson-Wood, S L, Kennedy, D, Kholodenko, J E, Knops, L H, Latimer, M, Lee, Z, Liao, I M, Lieberburg, R N, Motter, L C, Mutter, J, Nietz, K P, Quinn, K L, Sacchi, P A, Seubert, G M, Shopp, E D, Thorsett, J S, Tung, J, Wu, S, Yang, C T, Yin, D B, Schenk, P C, May, L D, Altstiel, M H, Bender, L N, Boggs, T C, Britton, J C, Clemens, D L, Czilli, D K, Dieckman-McGinty, J J, Droste, K S, Fuson, B D, Gitter, P A, Hyslop, E M, Johnstone, W Y, Li, S P, Little, T E, Mabry, F D, Miller, J E, Audia
Publikováno v:
Journal of neurochemistry. 76(1)
Converging lines of evidence implicate the beta-amyloid peptide (Ass) as causative in Alzheimer's disease. We describe a novel class of compounds that reduce A beta production by functionally inhibiting gamma-secretase, the activity responsible for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c6f79e4d7e1203f1957dee4deb0de9d
https://pubmed.ncbi.nlm.nih.gov/11145990
https://pubmed.ncbi.nlm.nih.gov/11145990
Autor:
J M, Silverman, D A, Greenberg, L D, Altstiel, L J, Siever, R C, Mohs, C J, Smith, G, Zhou, T E, Hollander, X P, Yang, M, Kedache, G, Li, M L, Zaccario, K L, Davis
Publikováno v:
American journal of medical genetics. 67(2)
We attempted to identify a locus for schizophrenia and related disorders in 24 nuclear families of schizophrenic probands using a predefined classification system for affected cases that included those disorders most clearly identified as sharing a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0c5cbf8faa345b331f358d458ea0893
https://pubmed.ncbi.nlm.nih.gov/8723043
https://pubmed.ncbi.nlm.nih.gov/8723043
Autor:
G, Li, J M, Silverman, L D, Altstiel, V, Haroutunian, D P, Perl, D, Purohit, S, Birstein, M, Lantz, R C, Mohs, K L, Davis
Publikováno v:
Genetic epidemiology. 13(3)
Recent studies have found an association between presence of apolipoprotein E (APOE) epsilon 4 allele and Alzheimer's disease (AD). The present study compared the cumulative risk of primary progressive dementia (PPD) in relatives of AD probands carry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5109b196780ea22839a791c04a8acee
https://pubmed.ncbi.nlm.nih.gov/8797010
https://pubmed.ncbi.nlm.nih.gov/8797010
Publikováno v:
Dementia (Basel, Switzerland). 6(1)
A portion of Alzheimer's disease (AD) patients have elevated serum levels of the acute phase reactant alpha 1-antichymotrypsin (A1ACT) compared to age-matched controls. We measured serum levels of A1ACT in AD patients, age-matched controls, Down's sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ed61edd4b262f000120ea52865f1557
https://pubmed.ncbi.nlm.nih.gov/7728215
https://pubmed.ncbi.nlm.nih.gov/7728215
Autor:
F R Landsberger, L D Altstiel
Publikováno v:
Journal of virology. 39(1)
Spin label electron spin resonance techniques using a nitroxide derivative of stearic acid were used to detect changes in plasma membrane structure caused by the binding of vesicular stomatitis virus (VSV) to cell plasma membranes of intact BHK-21 ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307d37e1b43e75b680f5113504642c88
https://pubmed.ncbi.nlm.nih.gov/6268823
https://pubmed.ncbi.nlm.nih.gov/6268823