Zobrazeno 1 - 10
of 21
pro vyhledávání: '"L Clark Paramore"'
Autor:
Katie D. Stewart, Hayley Karn, L Clark Paramore, Louis S. Matza, Minesh Jobanputra, Andrew C Dietz
Publikováno v:
The European Journal of Health Economics
Objectives Transfusion-dependent β-thalassemia (TDT) is a genetic disease that affects production of red blood cells. Conventional treatment involves regular red blood cell transfusions and iron chelation, which has a substantial impact on quality o
Publikováno v:
Clinical therapeutics. 42(2)
Purpose β-Thalassemia is an inherited blood disorder characterized by reduced or no production of adult hemoglobin. Systematic identification of the burden of β-thalassemia with contemporary treatments is lacking in published literature. Thus, a ga
Publikováno v:
Therapeutic innovationregulatory science. 50(5)
In a rapidly changing health care environment, it is more important than ever that pharmaceutical manufacturers improve the quality and efficiency of their research and development efforts in order to help ensure the right drug gets to the right pati
Publikováno v:
Expert Review of Clinical Pharmacology. 7:341-348
Acetaminophen is a commonly-used analgesic in the US and, at doses of more than 4 g/day, can lead to serious hepatotoxicity. Recent FDA and CMS decisions serve to limit and monitor exposure to high-dose acetaminophen. This literature review aims to d
Publikováno v:
Pediatric Pulmonology. 45:578-584
Objective To identify the frequency of outpatient, non-hospitalized visits for respiratory syncytial virus (RSV) lower respiratory tract infection (LRI) among children and high-risk infants. Study Design Published studies that reported population-bas
Publikováno v:
Current Medical Research and Opinion. 26:41-51
Forecast the return on investment (ROI) for advances in biologic therapies in years 2015 and 2030, based upon impact on disease prevalence, morbidity, and mortality for asthma, diabetes, and colorectal cancer. A deterministic, spreadsheet-based, fore
Autor:
Lynn J. Okamoto, Rami Ben-Joseph, L. Clark Paramore, Judith A. O'Brien, J. Jaime Caro, Eldon Spackman, Christopher S. Hollenbeak
Publikováno v:
Value in Health. 10:S12-S20
Objective The long-term risk of cardiovascular disease and diabetes have not been modeled for individuals with metabolic syndrome or other related cardiometabolic risk factors, nor have their long-term costs been estimated. Therefore, we used a Marko
Publikováno v:
Expert Review of Pharmacoeconomics & Outcomes Research. 5:695-703
Clinical trials represent the most scientifically valid study design for evaluating the safety and efficacy of new medical treatments. However, for pharmacoeconomic outcomes, the usual efficacy clinical trial may not always provide the appropriate ve
Publikováno v:
Journal of occupational and environmental medicine. 51(2)
Objectives: Study objectives were to determine the impact of migraine and severe headache on employer burden, resource utilization, and workplace productivity before and after a migraine education program; estimate the associated costs in an employed
Publikováno v:
Clinical colorectal cancer. 6(1)
Background This study examines the resource use patterns and costs of care for patients with incident metastatic colorectal cancer (mCRC) based on analyses of retrospective claims data from selected health plans in the United States. Patients and Met