Public T cell receptors confer high-avidity CD4 responses to HIV controllers

Autor: Pierre de Truchis, Mathieu Claireaux, Alexandre Nouël, Lisa A. Chakrabarti, Moran Galperin, Samia Hendou, Daniela Benati, Pierre Lechat, Brigitte Lemercier, Annick Lim, Fernando Arenzana-Seisdedos, Olivier Lambotte, Jean-François Delfraissy, Kristy-Anne Campbell, Jamie Rossjohn, Stephanie Gras, Faroudy Boufassa, Madhura Mukhopadhyay

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, 2016, ⟨10.1172/JCI83792⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2016, ⟨10.1172/JCI83792⟩

International audience; The rare patients who are able to spontaneously control HIV replication in the absence of therapy show signs of a particularly efficient cellular immune response. To identify the molecular determinants that underlie this respo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63f5ef9a7592cc37e40fe62b862aabb
https://europepmc.org/articles/PMC4887161/

Regulation of Mouse Intestinal L Cell Progenitors Proliferation by the Glucagon Family of Peptides

Autor: Maureen J. Charron, Marine Grigoryan, Mamdouh H. Kedees, Gladys Teitelman, Yelena Guz

Publikováno v: Endocrinology. 153:3076-3088

Glucagon like peptide-1 (GLP-1) and GLP-2 are hormones secreted by intestinal L cells that stimulate glucose-dependent insulin secretion and regulate intestinal growth, respectively. Mice with deletion of the glucagon receptor (Gcgr) have high levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32567e386535a2a8f243eb8e4106787
https://doi.org/10.1210/en.2012-1120

Mutations in the Glycoprotein of Vesicular Stomatitis Virus Affect Cytopathogenicity: Potential for Oncolytic Virotherapy

Autor: Alain Lamarre, Frédérick Brassard, Laurent Poliquin, Valérie Janelle, Pascal Lapierre

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2011, 85 (13), pp.6513-20. ⟨10.1128/JVI.02484-10⟩

Vesicular stomatitis virus (VSV) has been widely used to characterize cellular processes, viral resistance, and cytopathogenicity. Recently, VSV has also been used for oncolytic virotherapy due to its capacity to selectively lyse tumor cells. Mutants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f1a78ea426657d611a6513bce212a2
https://doi.org/10.1128/jvi.02484-10

Use of L-929 cell line for phototoxicity assessment

Autor: A. Sharma, Ratan Singh Ray, N. Agrawal, R.K. Hans

Publikováno v: Toxicology in Vitro. 22:1775-1781

L-929 is an adherent type of mouse fibroblast cell line was known as an alternate test system for toxicity assessment. Its photosensitivity towards ultraviolet radiation (UVR) was studied under the exposure to various intensities of UVA, UVB and sunl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86f26a907a383fa8604f21c5a67d035
https://doi.org/10.1016/j.tiv.2008.06.015

Protein Kinase Cζ Is Required for Oleic Acid-Induced Secretion of Glucagon-Like Peptide-1 by Intestinal Endocrine L Cells

Autor: Catharine I. Whiteside, Angelo Izzo, Andrea Yeung, Roman Iakoubov, Patricia L. Brubaker

Publikováno v: Endocrinology. 148:1089-1098

Long-chain, monounsaturated fatty acids (FAs) stimulate secretion of the incretin hormone, glucagon-like peptide-1 (GLP-1) from the intestinal L cell. Because the atypical protein kinase C (PKC), PKCζ, is involved in FA signaling in many cells, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ba846075c946851faa26585b894556
https://doi.org/10.1210/en.2006-1403