Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress.

Autor: Tiziana Triulzi, Patrizia Casalini, Marco Sandri, Manuela Ratti, Maria L Carcangiu, Mario P Colombo, Andrea Balsari, Sylvie Ménard, Rosaria Orlandi, Elda Tagliabue

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e56761 (2013)

We recently showed that differential expression of extracellular matrix (ECM) genes delineates four subgroups of breast carcinomas (ECM1, -2, -3- and -4) with different clinical outcome. To further investigate the characteristics of ECM signature and

Externí odkaz: https://doaj.org/article/14d7e5aa0d9c4ad38cc6cfb38df659c5

Whole-transcriptome analysis links trastuzumab sensitivity of breast tumors to both HER2 dependence and immune cell infiltration

Autor: Silvana Canevari, Andrea Balsari, Sylvie Ménard, Serena Di Cosimo, Marta Giussani, Aleix Prat, Marialuisa L. Carcangiu, Manuela Campiglio, Daniele Generali, Biagio Paolini, Elda Tagliabue, Loris De Cecco, Alberto Bottini, Tiziana Triulzi, Marco Sandri

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Oncotarget

While results thus far demonstrate the clinical benefit of trastuzumab, some patients do not respond to this therapy. To identify a molecular predictor of trastuzumab benefit, we conducted whole-transcriptome analysis of primary HER2+ breast carcinom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21b7d6b2dd4ea0dd52377a4379521d7
https://doi.org/10.18632/oncotarget.4405

Pitfalls in thyroid tumour pathology

Autor: J Rosai, M L Carcangiu, E Kuhn

Publikováno v: Histopathology. 49:107-120

This review provides an itemized listing of major diagnostic pitfalls in the field of thyroid tumour pathology, emphasizing the features that the authors have found most useful in their recognition and avoidance.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a84169ec408f8a8dae36a19f34b1767
https://doi.org/10.1111/j.1365-2559.2006.02451.x

A pilot study of topotecan in the treatment of serous carcinoma of the uterus

Autor: J. T. Chambers, T. J. Rutherford, P. E. Schwartz, M. L. Carcangiu, S. K. Chambers, L. Baker

Publikováno v: International Journal of Gynecologic Cancer. 13:216-222

A pilot study investigated topotecan (Hycamtin, GlaxoSmithKline, Philadelphia, PA), a topoisomerase I inhibitor, in treating uterine serous carcinoma, a typically unresponsive aggressive tumor. Fifteen patients were surgically staged, then treated wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50ad91bfa4134c74beea51f09a32bf8c
https://doi.org/10.1136/ijgc-00009577-200303000-00020

ß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasion

Autor: Francesca Di Sole, MariaLuisa L. Carcangiu, Loredana Moro, Ester Antelmi, Rosa Rubino, Nicola Antonio Martino, Stephan J. Reshkin, Valeria Casavola, Rosa Angela Cardone, Maria Raffaella Greco

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e75113 (2013)
PLoS ONE
PloS one 8 (2013). doi:10.1371/journal.pone.0075113
info:cnr-pdr/source/autori:Antelmi E.; Cardone R.A.; Greco M.R.; Rubino R.; Di Sole F.; Martino N.A.; Casavola V.; Carcangiu M.L.; Moro L.; Reshkin S.J./titolo:ß1 Integrin Binding Phosphorylates Ezrin at T567 to Activate a Lipid Raft Signalsome Driving Invadopodia Activity and Invasion/doi:10.1371%2Fjournal.pone.0075113/rivista:PloS one/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume:8

Extracellular matrix (ECM) degradation is a critical process in tumor cell invasion and requires matrix degrading protrusions called invadopodia. The Na(+)/H(+) exchanger (NHE1) has recently been shown to be fundamental in the regulation of invadopod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2843d7676dd6a3d43b50167e1a18340c
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086451/?tool=EBI