Zobrazeno 1 - 10
of 36
pro vyhledávání: '"L C Burkly"'
Autor:
Martin Pejchinovski, Harald Mischak, L. C. Burkly, Justyna Siwy, Ru Wei, Michelle Petri, William Mullen
Publikováno v:
Lupus. 27(1)
BackgroundSystematic lupus erythematosus (SLE) is characterized with various complications which can cause serious organ damage in the human body. Despite the significant improvements in disease management of SLE patients, the non-invasive diagnosis
The murine monoclonal antibody (MAb) 5A8, which is reactive with domain 2 of CD4, blocks human immunodeficiency virus type 1 (HIV-1) infection and syncytium formation of CD4+ cells (L. C. Burkly, D. Olson, R. Shapiro, G. Winkler, J. J. Rosa, D. W. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff4fac7b00435e08a83e9b8a7af4cca
https://ora.ox.ac.uk/objects/uuid:0fdc96e2-c0d4-4b1c-b703-488f52b8b718
https://ora.ox.ac.uk/objects/uuid:0fdc96e2-c0d4-4b1c-b703-488f52b8b718
Autor:
Esther Lutgens, Liangsu Wang, Marion J.J. Gijbels, Linda Beckers, M. M. J. Rousch, M. de Winther, Mat J.A.P. Daemen, L. C. Burkly, Sylvia Heeneman, N. O. Davidson
Publikováno v:
Journal of pathology, 212(4), 420-428. John Wiley and Sons Ltd
Embryonic pathways are often re-expressed in adult pathology. Here we investigated the role of the morphogen hedgehog (hh), which we found to be re-expressed in atherosclerotic plaques. Male ApoE − /− mice were treated for 12 weeks with an anti-h
Publikováno v:
The Journal of Experimental Medicine
The beta 1 subfamily of integrins is thought to play an important role in both the adhesion/migration and proliferation/differentiation of T cells. beta 1 integrins can provide T cell costimulation through interaction of very late antigen (VLA) 4 (VL
Publikováno v:
The Journal of Immunology. 155:938-946
The alpha 4 beta 1-integrin (CD49d, CD29) constitutively expressed on leukocytes regulates cell migration to inflammatory sites, cell activation, and development through its interactions with two alternate ligands, vascular cell adhesion molecule-1 (
Autor:
Satoshi Takaki, Taeko Dohi, Teruki Hagiwara, Kyoko Inagaki-Ohara, A Son, Yuki I. Kawamura, Tomoyuki Oshio, T Okada, M Yamazaki, Masanori Iseki, Ping Wu, L C Burkly
Publikováno v:
Mucosal immunology. 6(6)
Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK), a TNF superfamily member, induces damage of the epithelial cells (ECs) and production of inflammatory mediaters through its receptor Fn14 in a model of acute colitis. In our current
Publikováno v:
The Journal of Immunology. 151:3954-3960
A variety of cell types expressing MHC class II molecules is known to function as APC in vitro. We employed the Ig kappa gene enhancer and promoter to target the class II E alpha gene, and thereby I-E, exclusively to B cells to address their APC func
Publikováno v:
The Journal of Immunology. 149:1779-1787
HIV use the CD4 molecule as their primary cellular receptor. Residues in the N-terminal domain (D1) of CD4 are crucial to HIV attachment through the gp120 envelope component. However, other regions of CD4 appear to be required subsequently for virus-
Publikováno v:
Transplantation. 72(11)
Delayed xenograft rejection is associated with endothelial cell activation, platelet sequestration, and subsequent thrombosis. We evaluated whether human platelets could directly activate porcine endothelium (PEC), and if so, whether this was mediate
Autor:
E A, Elster, H, Xu, D K, Tadaki, S, Montgomery, L C, Burkly, J D, Berning, R E, Baumgartner, F, Cruzata, R, Marx, D M, Harlan, A D, Kirk
Publikováno v:
Transplantation. 72(9)
Allogeneic skin transplantation remains a rigorous test of any immune intervention designed to prevent allograft rejection. To date, no single, clinically available immunosuppressant has been reported to induce long-term primary skin allograft surviv