Zobrazeno 1 - 10
of 12
pro vyhledávání: '"L C, Moscinski"'
Publikováno v:
Hematology (Amsterdam, Netherlands). 6(1)
A 65-year-old patient with an IgM gammopathy, plasma cell infiltration of the bone marrow, lytic lesions of the skeleton, and symptoms of hyperviscosity was evaluated. A diagnosis of IgM myeloma was made. Treatment for multiple myeloma was initiated
Autor:
L. C. Moscinski, X. T. Hu
Publikováno v:
Cell Proliferation. 44:205-211
Cell cycle progression is controlled by both extracellular and intracellular signalling molecules. It has been generally believed that cdc2/CDK1 only control G(2)-M transition in mammalian and many other higher eukaryotic cells. Accumulating evidence
Publikováno v:
Blood. 83:1903-1908
Interleukin-6 (IL-6) is a multifunctional cytokine postulated to play a central role as a growth factor for multiple myeloma (MM). We evaluated the spontaneous secretion of IL-6 in supernatants of Ficoll-Hypaque-- enriched bone marrow (BM) cultures f
Autor:
X, Hu, W E, Janssen, L C, Moscinski, M, Bryington, A, Dangsupa, N, Rezai-Zadeh, B A, Babbin, K S, Zuckerman
Publikováno v:
Cancer research. 61(16)
Treatment of U937 cells with an IkappaBalpha phosphorylation inhibitor, Bay 11-7085, induced a rapid phosphorylation of p38 mitogen-activated protein (MAP) kinase, significant apoptosis, extensive necrosis, and a weak phosphorylation of MAP kinase ki
Publikováno v:
Anticancer research. 20(6B)
We have previously reported that invasiveness of mouse glioma G-26, which expresses CD44 adhesion molecule, was inhibited in vitro following treatment with anti-CD44 antibody or mouse interferon alpha/beta (MuIFN alpha/beta). Here, we evaluated wheth
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 11(4)
The role of the mitogen-activated protein kinase (MAPK) signal transduction pathway in the proliferation of mammalian cells has been well established. However, there are relatively few reports concerning cell differentiation being mediated by MAPK. T
Autor:
L L, Garland, O F, Ballester, F B, Vasey, K, Benson, L C, Moscinski, M J, Farmelo, M J, Rodriguez, D P, Rapaport
Publikováno v:
Current topics in microbiology and immunology. 210
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 6(6)
Summary Background The t(ll;14)(ql3;q32) is a chromosomal abnormality usually associated with mantle cell (centrocytic) lymphomas, although it has occasionally been reported in other chronic lymphoproliferative disorders such as chronic lymphocytic l
Publikováno v:
Cancer. 68(10)
Surface phenotyping by flow cytometry and cytochemical study were used to identify 15 adult patients with acute leukemia displaying ambiguous phenotypes. Differences were found in the blast cell karyotype and immunoglobulin gene rearrangements of ter
Autor:
L C, Moscinski, M B, Prystowsky
Publikováno v:
Oncogene. 5(1)
The production of terminally differentiated granulocytes and monocytes occurs by a program of orderly and sequential gene expression. This genetic program can be studied in vitro utilizing granulocyte-monocyte colony stimulating factor (GM-CSF) to st