Zobrazeno 1 - 2
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pro vyhledávání: '"L C, Everley"'
Autor:
C E, Szarka, G R, Pfeiffer, S T, Hum, L C, Everley, A M, Balshem, D F, Moore, S, Litwin, E B, Goosenberg, H, Frucht, P F, Engstrom
Publikováno v:
Cancer research. 55(13)
The glutathione S-transferases (alpha, mu, and pi), a family of Phase II detoxication enzymes, play a critical role in protecting the colon mucosa by catalyzing the conjugation of dietary carcinogens with glutathione. We investigated the efficacy of
Publikováno v:
Molecular pharmacology. 45(3)
The antischistosomal agent oltipraz displays a unique ability to inhibit chemically induced carcinogenesis in a variety of animal models. Its apparent lack of carcinogen specificity and low toxicity make it an attractive candidate for further develop