Zobrazeno 1 - 10
of 64
pro vyhledávání: '"L Bookout A"'
Autor:
Eduardo Vieira de Souza, Angie L. Bookout, Christopher A. Barnes, Brendan Miller, Pablo Machado, Luiz A. Basso, Cristiano V. Bizarro, Alan Saghatelian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract There has been a dramatic increase in the identification of non-canonical translation and a significant expansion of the protein-coding genome. Among the strategies used to identify unannotated small Open Reading Frames (smORFs) that encode
Externí odkaz:
https://doaj.org/article/13e4b549acb34d0093dff42c94e191d2
Autor:
Vieira de Souza, Eduardo, L. Bookout, Angie, Barnes, Christopher A., Miller, Brendan, Machado, Pablo, Basso, Luiz A., Bizarro, Cristiano V., Saghatelian, Alan
Publikováno v:
Nature Communications; 8/9/2024, Vol. 15 Issue 1, p1-14, 14p
Autor:
Deepali Gupta, Anna M. Patterson, Sherri Osborne-Lawrence, Angie L. Bookout, Salil Varshney, Kripa Shankar, Omprakash Singh, Nathan P. Metzger, Corine P. Richard, Steven C. Wyler, Joel K. Elmquist, Jeffrey M. Zigman
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101258- (2021)
Objective: Acyl-ghrelin regulates eating, body weight, blood glucose, and GH secretion upon binding to its receptor GHSR (growth hormone secretagogue receptor; ghrelin receptor). GHSR is distributed in several brain regions and some peripheral cell-t
Externí odkaz:
https://doaj.org/article/15aee9669cc940358b40f5b6dd06b885
Autor:
Swalpa Udit, Michael Burton, Joseph M. Rutkowski, Syann Lee, Angie L. Bookout, Philipp E. Scherer, Joel K. Elmquist, Laurent Gautron
Publikováno v:
Molecular Metabolism, Vol 6, Iss 10, Pp 1081-1091 (2017)
Objective and methods: Metabolic viscera and their vasculature are richly innervated by peripheral sensory neurons. Here, we examined the metabolic and inflammatory profiles of mice with selective ablation of all Nav1.8-expressing primary afferent ne
Externí odkaz:
https://doaj.org/article/d8a2f3041c25409fbb8edefb02a42dd9
Autor:
Marina K. Gerstenberg, Daniel B. Andersen, Lola Torz, Carlos M. Castorena, Angie L. Bookout, Bolette Hartmann, Jens F. Rehfeld, Natalia Petersen, Jens J. Holst, Rune E. Kuhre
Publikováno v:
Gerstenberg, M K, Andersen, D B, Torz, L, Castorena, C M, Bookout, A L, Hartmann, B, Rehfeld, J F, Petersen, N, Holst, J J & Kuhre, R E 2023, ' Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine ', Acta Physiologica, vol. 238, no. 1, e13947 . https://doi.org/10.1111/apha.13947
Aim: Postprandial secretion of the appetite-inhibiting hormones, glucagon-like peptide-1 (GLP-1), and peptide YY are reduced with obesity. It is unclear if the reduced secretion persists following weight loss (WL), if other appetite-inhibiting hormon
Autor:
Chaitanya K. Gavini, Angie L. Bookout, Raiza Bonomo, Laurent Gautron, Syann Lee, Virginie Mansuy-Aubert
Publikováno v:
Cell Reports, Vol 25, Iss 2, Pp 271-277.e4 (2018)
Summary: Obesity is associated with many complications, including type 2 diabetes and painful neuropathy. There is no cure or prevention for obesity-induced pain, and the neurobiology underlying the onset of the disease is still obscure. In this stud
Externí odkaz:
https://doaj.org/article/da47ffdfcb4e4a60a63a84bba0bbe76a
Autor:
Kedryn K Baskin, Chad E Grueter, Christine M Kusminski, William L Holland, Angie L Bookout, Santosh Satapati, Y Megan Kong, Shawn C Burgess, Craig R Malloy, Philipp E Scherer, Christopher B Newgard, Rhonda Bassel‐Duby, Eric N Olson
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 12, Pp 1610-1621 (2014)
Abstract The heart requires a continuous supply of energy but has little capacity for energy storage and thus relies on exogenous metabolic sources. We previously showed that cardiac MED13 modulates systemic energy homeostasis in mice. Here, we sough
Externí odkaz:
https://doaj.org/article/30c5796f91024edaa0e87fbd9613c8d6
Autor:
Thomas F. Martinez, Sally Lyons-Abbott, Angie L. Bookout, Cynthia Donaldson, Joan M. Vaughan, Calvin Lau, Ariel Abramov, Arian F. Baquero, Karalee Baquero, Dave Friedrich, Justin Huard, Ray Davis, Bong Kim, Ty Koch, Aaron J. Mercer, Ayesha Misquith, Sara A. Murray, Sakara Perry, Lindsay K. Pino, Christina Sanford, Alex Simon, Yu Zhang, Garrett Zipp, Maxim N. Shokhirev, Andrew J. Whittle, Brian C. Searle, Michael J. MacCoss, Alan Saghatelian, Christopher A. Barnes
SUMMARYThe absence of thousands of recently annotated small open reading frame (smORF)-encoded peptides and small proteins (microproteins) from databases has precluded their analysis in metabolism and metabolic disease. Given the outsized importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c60053f4cebe996605878d3dbc60b0b
https://doi.org/10.1101/2022.03.12.484025
https://doi.org/10.1101/2022.03.12.484025
Autor:
Jen-Chieh Chuang, Huxing Cui, Brittany L. Mason, Melissa Mahgoub, Angie L. Bookout, Hana G. Yu, Mario Perello, Joel K. Elmquist, Joyce J. Repa, Jeffrey M. Zigman, Michael Lutter
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 6, Pp 1344-1353 (2010)
Several psychiatric disorders increase the risk of cardiovascular disease, including posttraumatic stress disorder and major depression. While the precise mechanism for this association has not yet been established, it has been shown that certain dis
Externí odkaz:
https://doaj.org/article/3253203346464118b4d9f82d4af89969
Autor:
Yang eLiu, Ying eHuang, Syann eLee, Angie L Bookout, Carlos M Castorena, Wua eHu, Laurent eGautron
Publikováno v:
Frontiers in Neuroanatomy, Vol 9 (2015)
Peroxisome proliferator-activated receptor gamma (PPARg) is a ligand-activated transcription factor that was originally identified as a regulator of peroxisome proliferation and adipocyte differentiation. Emerging evidence suggests that functional PP
Externí odkaz:
https://doaj.org/article/12defe3403124589aaca8e9aa1c3264c