A role for the cortex in sleep–wake regulation

Autor: Vincent van der Vinne, C Blanco-Duque, L B Krone, Vladyslav V. Vyazovskiy, Shu K. E. Tam, T Yamagata, M C Kahn, Anna Hoerder-Suabedissen, Zoltán Molnár, Stuart N. Peirson, Colin J. Akerman, Mathilde C. C. Guillaumin, L E McKillop

Publikováno v: Nature neuroscience

Cortical and subcortical circuitry are thought to play distinct roles in the generation of sleep oscillations and global state control, respectively. Here we silenced a subset of neocortical layer 5 pyramidal and archicortical dentate gyrus granule c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08969dbb94707344e1e23da57e5d6eab
https://doi.org/10.1038/s41593-021-00894-6

Differential effects of bifrontal tDCS on arousal and sleep duration in insomnia patients and healthy controls

Autor: Hannah Piosczyk, Michael A. Nitsche, Sulamith Tsodor, Annette Sterr, Marion Kuhn, Christoph Nissen, Stefan Klöppel, Dieter Riemann, Friederike Jahn, Bernd Feige, Jonathan G. Maier, Kai Spiegelhalder, Peter Selhausen, Lukas Frase, L B Krone, Florian Mainberger, Chiara Baglioni

Publikováno v: Brain Stimulation, Vol 12, Iss 3, Pp 674-683 (2019)

Background:Arousal and sleep represent basic domains of behavior, and alterations are of high clinical importance. Objective/hypothesis:The aim of this study was to further elucidate the neurobiology of insomnia disorder (ID) and the potential for ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9da798d967e0ed60c637f6fd1a9451
https://doi.org/10.1016/j.brs.2019.01.001

Diazepam effects on local cortical neural activity during sleep in mice

Autor: L Milinski, Simon P. Fisher, L B Krone, Vladyslav V. Vyazovskiy, L E McKillop

Publikováno v: Biochemical Pharmacology

Graphical abstract
GABA-ergic neurotransmission plays a key role in sleep regulatory mechanisms and in brain oscillations during sleep. Benzodiazepines such as diazepam are known to induce sedation and promote sleep, however, EEG spectral power

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4f138bedd521ad4c954917fa8634f6
http://europepmc.org/articles/PMC8363939

Offline Bi-Frontal Anodal Transcranial Direct Current Stimulation Decreases Total Sleep Time Without Disturbing Overnight Memory Consolidation

Autor: Lukas Frase, L B Krone, Jonathan G. Maier, Peter Selhausen, Bernd Feige, Christoph Nissen, Hannah Piosczyk, Dieter Riemann, Michael A. Nitsche, Sulamith Tsodor, Friederike Jahn

Publikováno v: Frase, Lukas; Jahn, Friederike; Tsodor, Sulamith; Krone, Lukas; Selhausen, Peter; Feige, Bernd; Maier, Jonathan G.; Piosczyk, Hannah; Riemann, Dieter; Nitsche, Michael A.; Nissen, Christoph (2021). Offline Bi-Frontal Anodal Transcranial Direct Current Stimulation Decreases Total Sleep Time Without Disturbing Overnight Memory Consolidation. Neuromodulation, 24(5), pp. 910-915. Wiley 10.1111/ner.13163

Objectives: A proposed replay of memory traces between the hippocampus and frontal cortical brain areas during sleep is of high relevance for overnight memory consolidation. Recently, we demonstrated that bi-frontal anodal transcranial direct current

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f24ab09aaa431a92fedaeb332828913
https://pubmed.ncbi.nlm.nih.gov/32394544

Sleep, insomnia, and depression

Autor: Katharina Wulff, Christoph Nissen, Dieter Riemann, L B Krone

Publikováno v: Neuropsychopharmacology

Since ancient times it is known that melancholia and sleep disturbances co-occur. The introduction of polysomnography into psychiatric research confirmed a disturbance of sleep continuity in patients with depression, revealing not only a decrease in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3179c85a03b0ed09da020db2bef13f