Zobrazeno 1 - 10
of 47
pro vyhledávání: '"L B Epstein"'
Publikováno v:
The Journal of Immunology. 150:5696-5703
The interaction between lymphocyte function-associated antigen 1 (LFA-1) on thymocytes and intercellular adhesion molecule 1 (ICAM-1) on the thymic stroma plays an important role in thymocyte maturation. Consequently, we examined the constitutive exp
Publikováno v:
The Journal of Immunology. 149:2506-2512
In vitro studies suggest that TNF-alpha and IFN-gamma regulate thymocyte proliferation, but little evidence exists for the constitutive production of these cytokines in normal human thymus. In paired experiments, we examined frozen sections of postna
Publikováno v:
The Journal of Immunology. 147:149-154
We have previously characterized more than 20 proteins induced by the immunoregulatory lymphokine IFN-gamma in human fibroblasts by their m.w. and isoelectric points determined in two-dimensional gels. Some of these proteins are induced uniquely by I
Publikováno v:
Electrophoresis. 11:232-241
Tumor necrosis factor (TNF) synergistically enhanced the antiproliferative activity of interferon-gamma (IFN-gamma) in both TNF-sensitive and TNF-resistant variants of the cervical carcinoma line, ME-180. TNF alone had no apparent effect on the level
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 112
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 112
Publikováno v:
Progress in clinical and biological research. 393
Publikováno v:
The Journal of biological chemistry. 269(13)
We have demonstrated that A375 melanoma cells express mRNA for both types of tumor necrosis factor (TNF) receptors and receptor proteins on their plasma membranes. Specific agonist and blocking antibodies to either 55-kDa (TNF-R1) or 75-kDa (TNF-R2)
Publikováno v:
Thymus. 23(3-4)
Although tumor necrosis factor-alpha (TNF) is constitutively expressed in human and mouse thymus, the effects of TNF on thymocyte proliferation, differentiation and survival suggest that its influence in the thymus is complex. To determine if this co