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Immunological basis for protection in a murine model of tick-borne encephalitis by a recombinant adenovirus carrying the gene encoding the NS1 non-structural protein

Autor: Galina G. Karganova, L B Elbert, S. V. Ozherelkov, A V Pronin, A V Timofeev, Deeva Av, J. R. Stephenson

Publikováno v: The Journal of general virology. 79

The humoral immune response to flaviviruses is mainly directed to the major envelope protein, E, and a glycosylated non-structural protein, NS1. Cell-mediated immune responses, however, appear to be directed mainly against non-structural proteins. Ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ea48e7e3b7d0e6848ddc1a179293dd
https://pubmed.ncbi.nlm.nih.gov/9568962

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[A recombinant adenovirus expressing the NS1 nonstructural protein of tick-borne encephalitis virus: some characteristics of the immunologic basis of antiviral action]

Autor: A V, Timofeev, S V, Ozherelkov, A V, Pronin, A V, Deeva, L B, Elbert, J R, Stefenson

Publikováno v: Voprosy virusologii. 42(5)

Recombinant adenovirus expressing NS1 nonstructural protein of trick-borne encephalitis (TBE) virus (Rad 51) protected mice from many strains of TBE and Omsk hemorhagic fever (OHF) viruses, but virtually did not protect them from Negishi virus. Durin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc6b60758826ed98b766d553f74fcdc2
https://pubmed.ncbi.nlm.nih.gov/9424847

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pH-dependent fusion of tick-borne encephalitis virus with artificial membranes

Autor: S. N. Atanadze, A. V. Timofeev, M. F. Vorovitch, Alla A. Kushch, L. B. Elbert, Sharof M. Tugizov

Publikováno v: Archives of virology. 118(1-2)

pH-dependent fusion of TBE virus with artificial membranes was effective at slightly acidic pH with maximum at 6.4. The influence of various changes in E protein conformation on fusion process was studied.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62adf8f11a7a3fa90ba30f8d527db10d
https://pubmed.ncbi.nlm.nih.gov/2048972

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Comparative study of infectious and formaldehyde-inactivated tick-borne encephalitis virus particles

Autor: S. G. Sobolev, M. K. Khanina, L. B. Elbert, I. V. Krasilnikov

Publikováno v: Archives of Virology. 79:241-253

The structure and properties of infectious and formaldehyde-treated particles of tick-borne encephalitis virus, concentrated and purified by chromatography on macroporous glass, were studied. In addition to complete virions, such preparations contain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a265ac94ef7938d1ac35d0ade25fe633
https://doi.org/10.1007/bf01310814

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Virus-induced blast transformation of lymphocytes and its inhibition by F(ab1)2 fragments of human IgG

Autor: Pervikov YuV, G U, Margulis, L B, Elbert, Kulberg AYaU, F S, Baranova

Publikováno v: Acta virologica. 25(3)

Blast transformation of lymphocytes from persons immunized by vaccines against tick-borne Japanese encephalitides, in response to stimulation by homologous viral antigens was studied. 3H-Thymidine incorporation into lymphocytes was completely inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::124a0cfc0b3fc9e118a98875321500ee
https://pubmed.ncbi.nlm.nih.gov/6115565

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Purification of tick-borne encephalitis virus in tris-modified porous glasses

Autor: I V, Krasilnikov, L B, Elbert, V N, Borisova, L A, Nakhapetyan

Publikováno v: Acta virologica. 29(4)

Macroporous glasses, chemically modified by tris-hydroxymethyl-aminomethane, were used for gel-permeation chromatography of tick-borne encephalitis (TBE) virus suspension. The highest yield of purified virus was observed in the carriers containing no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76222bb735ec60276d811e2b3a24da7e
https://pubmed.ncbi.nlm.nih.gov/2864829

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On the nature of the cystine-dependent phenotype of poliovirus

Autor: L. B. Elbert, V. M. Zaides, Vadim I. Agol, S. V. Maslova

Publikováno v: Archiv fur die gesamte Virusforschung. 23(3)

The mechanism of the phenotypic expression of a cyd mutation of poliomyelitis virus manifested by marked decrease of infectious virus particle yields in the absence of cystine, was studied. Cystine was shown to exert no marked effect on the synthesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12096b3abb684227cbe7e34924c689d7
https://pubmed.ncbi.nlm.nih.gov/4176043

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