Zobrazeno 1 - 10
of 39
pro vyhledávání: '"L B, Davis"'
Publikováno v:
Journal of Climate. 35:5119-5136
Thermodynamical and dynamical aspects of the climate system response to anthropogenic forcing are often considered in two distinct frameworks: the former in the context of the forcing–feedback framework, and the latter in the context of eddy–mean
Autor:
Lydiah Mutumbi, Guido Ferrari, Jennifer Schwartz, Charles E. L. B. Davis, Kelli Greene, Robin Flinko, Monica W. Gerber, Jennifer Husson, Raphael Gottardo, Amy Nelson, Joel V Chua, Celia Mahoney, Bruce L. Gilliam, Ka Wing J. Lam, George K. Lewis, Robert C. Gallo, Ilia Prado, Hongmei Gao, Georgia D. Tomaras, Dan Dong, William Fulp, Timothy R. Fouts, Nicole L. Yates, Mohammad M. Sajadi, Anthony L. DeVico, Bryan T. Mayer, David C. Montefiori
Publikováno v:
Vaccine
A major challenge for HIV vaccine development is to raise anti-envelope antibodies capable of recognizing and neutralizing diverse strains of HIV-1. Accordingly, a full length single chain (FLSC) of gp120-CD4 chimeric vaccine construct was designed t
Autor:
Bruce L. Gilliam, Kristen A Stafford, Charles E. L. B. Davis, Mohammad M. Sajadi, Joel Chua, Robert C. Gallo, William Fulp, Bryan T. Mayer, Dan Dong
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 84:37-44
OBJECTIVE Vaccines and biologics containing CD4 molecules or HIV-1 gp120 might induce antibodies targeting CD4. We evaluated temporal variability of CD4 levels in healthy volunteers to quantify declines that could indicate true adverse events. DESIGN
Publikováno v:
The Yale journal of biology and medicine. 95(1)
Prenatal stress is a neuropsychiatric risk factor, and effects may be mediated by prenatal oxidative stress. Cell types in the brain sensitive to oxidative stress-cortical microglia and cortical and hippocampal interneurons-may be altered by oxidativ
Biases in sea-surface temperature observations lead to larger uncertainties in our understanding of mid-to-late 20th century climate variability than previously thought. A new analysis of sea-surface temperature (SST) observations indicates notable u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50214db1f7a1bd2b417da962c17bdd1d
Autor:
Mohammad M. Sajadi, Kristen A Stafford, Joel V Chua, Bruce L. Gilliam, George K. Lewis, Anthony L. DeVico, Charles E. L. B. Davis, Ka Wing J. Lam, Amy Nelson, Lydiah Mutumbi
Publikováno v:
Open Forum Infectious Diseases
Background A primary challenge for HIV vaccine development is to raise antiviral antibodies capable of recognizing highly variable viral antigens. The full-length single chain (FLSC) gp120-CD4 chimeric protein was designed to present a highly conserv
Autor:
Nhut Le, Alonso Heredia, Edward A. Sausville, Charles E. L. B. Davis, Sandra Medina-Moreno, Ronald B. Gartenhaus, Robert C. Gallo, Robert R. Redfield, Juan C. Zapata
Publikováno v:
Proceedings of the National Academy of Sciences. 112:9412-9417
HIV necessitates host factors for successful completion of its life cycle. Mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that forms two complexes, mTORC1 and mTORC2. Rapamycin is an allosteric inhibitor of mTOR that sele
Autor:
T. Sparkes, Anthony Amoroso, Wana Manitpisitkul, Abdolreza Haririan, Stephen T. Bartlett, Jennifer Husson, Charles E. L. B. Davis, B. Masters
Publikováno v:
Transplant infectious disease : an official journal of the Transplantation Society. 20(6)
Background Protease inhibitors (PI) pose a challenge post-transplant due to significant drug interactions with calcineurin inhibitors, prompting many clinicians to convert patients to non-interacting regimens prior to transplant. The purpose of this
Autor:
Said Hassounah, Nhut Le, Alonso Heredia, Yingshan Han, Robert R. Redfield, Mark A. Wainberg, Joseph Bryant, Charles E. L. B. Davis, Juan C. Zapata, James S. Foulke, Sandra Medina-Moreno
To compare the effectiveness of HIV integrase inhibitor monotherapy between raltegravir and dolutegravir as an approach to simplify therapy.We evaluated and compared the efficacy of 20 week monotherapy with dolutegravir or raltegravir in humanized mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3eeedc66f9c0f301ff7c95945bc0e46
https://europepmc.org/articles/PMC5890682/
https://europepmc.org/articles/PMC5890682/
Autor:
Charles E. L. B. Davis, Augusta Whitney, Elisa J. Knutsen, Robert V OʼToole, Edward H. Becker, Alec Stall, Adam H. Hsieh
Publikováno v:
Journal of Orthopaedic Trauma. 26:216-221
OBJECTIVE To determine whether locking plates offer an advantage in fixation of fractures in osteoporotic humeral bone. DESIGN Biomechanical testing of 18 matched pairs of osteoporotic human cadaver humeri plated posteriorly with either all locked or