Zobrazeno 1 - 10
of 66
pro vyhledávání: '"L Alex Gaither"'
Autor:
Anke Bill, Elizabeth M Rosethorne, Toby C Kent, Lindsay Fawcett, Lynn Burchell, Michiel T van Diepen, Anthony Marelli, Sergey Batalov, Loren Miraglia, Anthony P Orth, Nicole A Renaud, Steven J Charlton, Martin Gosling, L Alex Gaither, Paul J Groot-Kormelink
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97973 (2014)
The human prostacyclin receptor (hIP receptor) is a seven-transmembrane G protein-coupled receptor (GPCR) that plays a critical role in vascular smooth muscle relaxation and platelet aggregation. hIP receptor dysfunction has been implicated in numero
Externí odkaz:
https://doaj.org/article/80aa82d5e7004c4f828cf2a96b6d0895
Autor:
Natalie M Niemi, Juliana L Sacoman, Laura M Westrate, L Alex Gaither, Nathan J Lanning, Katie R Martin, Jeffrey P MacKeigan
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93896 (2014)
We previously performed an RNA interference (RNAi) screen and found that the knockdown of the catalytically inactive phosphatase, MK-STYX [MAPK (mitogen-activated protein kinase) phospho-serine/threonine/tyrosine-binding protein], resulted in potent
Externí odkaz:
https://doaj.org/article/b26aeef4ccdd4e76aec60b6c28ef6526
Autor:
Diana Graus-Porta, William R. Sellers, Francesco Hofmann, Carlos Garcia-Echeverria, David M. Thomas, Thomas Brümmendorf, Kavitha Venkatesan, John E. Monahan, Jason Borawski, L. Alex Gaither, Mickaël Le Douget, Vincent Bordas, Christopher J. Wilson, Zhi Chen, Yun Zhang, Fang Li, Yao Yao, Astrid Pornon, Louise Barys, Moriko Ito, Christelle Stamm, Simon Wöhrle, Audrey Kauffmann, Vito Guagnano
PDF file - 1.4MB, Response to NVP-BGJ398; FGFR pathway modulation by NVP-BGJ398; NVP-BGJ398 - predictive features; FGFR2-c3 mRNA expression in cell lines and FGFR2 DNA copy number in tumors; FGF19 DNA copy number in CCLE cell lines and FGFR3 DNA copy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055d71ccbe50a65e308a5319a0af558a
https://doi.org/10.1158/2159-8290.22529469
https://doi.org/10.1158/2159-8290.22529469
Autor:
Diana Graus-Porta, William R. Sellers, Francesco Hofmann, Carlos Garcia-Echeverria, David M. Thomas, Thomas Brümmendorf, Kavitha Venkatesan, John E. Monahan, Jason Borawski, L. Alex Gaither, Mickaël Le Douget, Vincent Bordas, Christopher J. Wilson, Zhi Chen, Yun Zhang, Fang Li, Yao Yao, Astrid Pornon, Louise Barys, Moriko Ito, Christelle Stamm, Simon Wöhrle, Audrey Kauffmann, Vito Guagnano
XML file - 99K, Kinase activity and selectivity for NVP-BGJ398; CCLE cell lines sensitive to NVP-BGJ398; GeneSet expression signatures; FGFR genetic alterations and concomitant mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394b8c19ed3865b26c4b23f7077d34aa
https://doi.org/10.1158/2159-8290.22529463.v1
https://doi.org/10.1158/2159-8290.22529463.v1
Autor:
Diana Graus-Porta, William R. Sellers, Francesco Hofmann, Carlos Garcia-Echeverria, David M. Thomas, Thomas Brümmendorf, Kavitha Venkatesan, John E. Monahan, Jason Borawski, L. Alex Gaither, Mickaël Le Douget, Vincent Bordas, Christopher J. Wilson, Zhi Chen, Yun Zhang, Fang Li, Yao Yao, Astrid Pornon, Louise Barys, Moriko Ito, Christelle Stamm, Simon Wöhrle, Audrey Kauffmann, Vito Guagnano
XML file - 56K, High throughput pharmacological screen of BGJ398 in 517 cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2881a9c58817a03993b13427e5d262a1
https://doi.org/10.1158/2159-8290.22529466.v1
https://doi.org/10.1158/2159-8290.22529466.v1
Autor:
Paloma Bragado, Pere Gascon, Joan Albanell, Ana Lluch, Ana Rovira, Elisabet Ametller, Raul Alonso, Núria Moragas, Leire Recalde-Percaz, Laia Serrano, L. Alex Gaither, Anke Bill, Aleix Noguera-Castells, Federico Rojo, Silvia Menéndez, Estel Enreig, Vanesa Almendro, Patricia Jauregui, Anna López-Plana, Gemma Fuster, Mario Mancino, Patricia Fernández-Nogueira
Fibroblast effect on HER2 activation and HER2-targeted therapies sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09231ac70523ec6b34a3bc7388d36ca9
https://doi.org/10.1158/1078-0432.22473389
https://doi.org/10.1158/1078-0432.22473389
Autor:
Umamaheswar Duvvuri, Manojkumar A. Puthenveedu, L. Alex Gaither, Jennifer Grandis, Patrick Ha, Jeffery N. Myers, Daisuke Sano, Raja S. Seethala, Carol A. Bertrand, Dong Xiao, Jean Kim, Anke Bill, Chunbo Shao, Daniel J. Shiwarski
PDF file - 196K, Table summarizing the antibodies used for immunoblotting and IHC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ca6088f97981473549b409f3cf2815
https://doi.org/10.1158/1078-0432.22455696.v1
https://doi.org/10.1158/1078-0432.22455696.v1
Autor:
Umamaheswar Duvvuri, Manojkumar A. Puthenveedu, L. Alex Gaither, Jennifer Grandis, Patrick Ha, Jeffery N. Myers, Daisuke Sano, Raja S. Seethala, Carol A. Bertrand, Dong Xiao, Jean Kim, Anke Bill, Chunbo Shao, Daniel J. Shiwarski
PDF file - 202K, Knockdown of TMEM16A in T24 cancer cells decreases motility and migration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c248edde1e60f2364ebda9cf569a949
https://doi.org/10.1158/1078-0432.22455726.v1
https://doi.org/10.1158/1078-0432.22455726.v1
Autor:
Umamaheswar Duvvuri, Manojkumar A. Puthenveedu, L. Alex Gaither, Jennifer Grandis, Patrick Ha, Jeffery N. Myers, Daisuke Sano, Raja S. Seethala, Carol A. Bertrand, Dong Xiao, Jean Kim, Anke Bill, Chunbo Shao, Daniel J. Shiwarski
PDF file - 133K, Table summarizing the data from Figure 6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0eb5d31f49b1413fcb88302d38bfd1
https://doi.org/10.1158/1078-0432.22455699
https://doi.org/10.1158/1078-0432.22455699
Autor:
Umamaheswar Duvvuri, Manojkumar A. Puthenveedu, L. Alex Gaither, Jennifer Grandis, Patrick Ha, Jeffery N. Myers, Daisuke Sano, Raja S. Seethala, Carol A. Bertrand, Dong Xiao, Jean Kim, Anke Bill, Chunbo Shao, Daniel J. Shiwarski
PDF file - 132K, TMEM16A expression influences cell size measured via flow cytometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cf608103bf8d6aaa30c001d054b977
https://doi.org/10.1158/1078-0432.22455717
https://doi.org/10.1158/1078-0432.22455717