Zobrazeno 1 - 10
of 97
pro vyhledávání: '"L A Zech"'
Autor:
R D Shamburek, P G Pentchev, L A Zech, J Blanchette-Mackie, E D Carstea, J M VandenBroek, P S Cooper, E B Neufeld, R D Phair, H B Brewer, Jr, R O Brady, C C Schwartz
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 12, Pp 2422-2435 (1997)
Niemann-Pick C disease (NP-C) is a rare inborn error of metabolism with hepatic involvement and neurological sequelae that usually manifest in childhood. Although in vitro studies have shown that the lysosomal distribution of LDL-derived cholesterol
Externí odkaz:
https://doaj.org/article/55306360d4814767a73496af294e7219
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 2, Pp 399-407 (1996)
ApoA-II is a major apolipoprotein constituent of high density lipoproteins (HDL) and may play an important role in lipoprotein metabolism and predisposition to atherosclerosis. Previous radiotracer kinetic studies have suggested that the metabolism o
Externí odkaz:
https://doaj.org/article/c25bf249351e45c0b4de6b082d6a8d33
Autor:
W R Fisher, V Venkatakrishnan, L A Zech, C M Hall, L L Kilgore, P W Stacpoole, M R Diffenderfer, K E Friday, A E Sumner, J B Marsh
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 7, Pp 1618-1628 (1995)
The kinetics of apolipoproteins A-I and A-II were examined in human subjects using leucine tracers administered intravenously. High density lipoproteins were separated and apoA-I and A-II were isolated. The specific activity or enrichment data for th
Externí odkaz:
https://doaj.org/article/9b46670b53a249ddb0b67d9d1efa0eea
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 10, Pp 1809-1819 (1994)
The metabolism of high density lipoproteins (HDL) is tightly linked to the metabolism of apoB-containing lipoproteins through the exchange and transfer of lipids and apolipoproteins within the plasma compartment. Abetalipoproteinemia (ABL), a genetic
Externí odkaz:
https://doaj.org/article/158c7e6944234bd48db3672363a24371
Publikováno v:
Journal of Lipid Research, Vol 34, Iss 12, Pp 2207-2215 (1993)
Apolipoprotein A-I is the major apolipoprotein constituent of high density lipoproteins (HDL). Methods used to investigate in vivo kinetics of apoA-I include exogenous labeling with radioiodine and endogenous labeling with stable isotopically labeled
Externí odkaz:
https://doaj.org/article/c03c803c27074aca9bb76a8104faf7c8
Autor:
H G Klein, P Lohse, N Duverger, J J Albers, D J Rader, L A Zech, S Santamarina-Fojo, HB Brewer, Jr
Publikováno v:
Journal of Lipid Research, Vol 34, Iss 1, Pp 49-58 (1993)
The molecular defects in the lecithin:cholesterol acyltransferase (LCAT) gene have been identified in a 52-year-old patient with classic LCAT deficiency, presenting with corneal clouding and proteinuria. Plasma total cholesterol was normal, triglycer
Externí odkaz:
https://doaj.org/article/738c03cdf794403fbcbed85e05382701
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 6, Pp 760-774 (1980)
This research concerns the metabolism of apolipoprotein B (apoB) in hypertriglyceridemic subjects with polydisperse or heterogeneous LDL. Five subjects maintained under constant dietary control had blood samples fractionated into very low density lip
Externí odkaz:
https://doaj.org/article/10f83755c9884b5aa5674625574876a2
Autor:
E J Schaefer, D W Anderson, L A Zech, F T Lindgren, T B Bronzert, E A Rubalcaba, H B Brewer, Jr
Publikováno v:
Journal of Lipid Research, Vol 22, Iss 2, Pp 217-228 (1981)
The metabolism of apolipoproteins A-I and A-II, as well as other high density lipoprotein (HDL) constituents, was studied in patients with homozygous familial HDL deficiency (Tangier disease) prior to and after plasma exchange or HDL infusion. Mean p
Externí odkaz:
https://doaj.org/article/3cb78206fcc248248cd0806cc0c7ee9b
Publikováno v:
Journal of Lipid Research, Vol 24, Iss 1, Pp 60-71 (1983)
The metabolism of radioiodinated apolipoproteins (apo) A-I and A-II have been examined using the techniques of compartmental modeling. The model for apoA-I contains two plasma compartments decaying at different rates. One component of apoA-I has a re
Externí odkaz:
https://doaj.org/article/23fd985b7a29489cb3961489419b1d1a
Autor:
E J Schaefer, L A Zech, L L Jenkins, T J Bronzert, E A Rubalcaba, F T Lindgren, R L Aamodt, H B Brewer, Jr
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 6, Pp 850-862 (1982)
The kinetics of the major apolipoproteins (apo) of plasma high density lipoproteins (HDL), apoA-I and apoA-II, were examined in a total of 44 individual tracer studies in 22 normal male and female subjects. Following the intravenous injection of radi
Externí odkaz:
https://doaj.org/article/fbb8cc26ed854cfea5f8c8a25ab48cf2